Found 9617 Results / Page 356 of 481
2017 / Journal of Applied Biomedicine
Amyloidosis is a group of diseases caused by the accumulation of insoluble protein aggregates in different parts of the body.… Continue reading Lumbrokinase for degradation and reduction of amyloid fibrils associated with amyloidosis
2017 / Journal of Inorganic Biochemistry
The spectroscopic and functional properties of the single Met80Ala and double Tyr67His/Met80Ala mutants of human cytochrome c have been investigated… Continue reading The Met80Ala and Tyr67His/Met80Ala mutants of human cytochrome c shed light on the reciprocal role of Met80 and Tyr67 in regulating ligand access into the heme pocket
2017 / International Journal of Biological Macromolecules
The present work deals with investigating the role of ionic interactions in the native conformation of BmGK by altering pH… Continue reading Delineating the role of ionic interactions in structural and functional integrity of B. malayi Guanylate Kinase
2017 / Nature Communications
C-reactive protein (CRP) concentrations rise in response to tissue injury or infection. Circulating pentameric CRP (pCRP) localizes to damaged tissue… Continue reading Transitional changes in the CRP structure lead to the exposure of proinflammatory binding sites
2017 / Applied Organmetallic Chemistry
Three water‐soluble complexes, [Cu2L2Cl2] (1), [CoL2(im)2] (2) and [ZnLClH2O] (3) (HL = 8‐hydroxyquinoline‐5‐sulphonic acid; im = N‐methylimidazole), were prepared and… Continue reading Synthesis and characterization of water-soluble copper(II), cobalt(II) and zinc(II) complexes derived from 8-hydroxyquinoline-5-sulphonic acid: DNA binding and cleavage studies
2017 / Peptides
The term “oxidative stress” indicates a set of chemical reactions unleashed by a disparate number of events inducing DNA damage,… Continue reading Trifluoroacetylated tyrosine-rich D-tetrapeptides have potent antioxidant activity
2017 / Colloids and Surfaces B: Biointerfaces
The present study explores preparation and characterization of redox sensitive albumin autogenic nanoparticles (ANPs) for drug delivery applications. Human serum… Continue reading Redox responsive albumin autogenic nanoparticles for the delivery of cancer drugs
2017 / Journal of Molecular Biology
To identify and structurally characterize the precursor conformation of the prion protein (PrP), from which misfolding and aggregation directly commence,… Continue reading Identification and structural characterization of the precursor conformation of the prion protein which directly initiates misfolding and oligomerization ☆
2017 / Internation Journal of Biological Macromolecules
Glucoamylase (EC 3.2.1.3) from Aspergillus niger possesses 31% α-helix, 36% β structure and rest aperiodic structure. A transition of glucoamylase in presence… Continue reading Secondary structural alterations in glucoamylase as an influence of protein aggregation
2017 / Internation Journal of Biological Macromolecules
Formation of amyloid fibrils has been associated with at least 30 different protein aggregation diseases. The 129-residue polypeptide hen lysozyme,… Continue reading Investigating the effects of erythrosine B on amyloid fibril formation derived from lysozyme
2017 / Biochimica et Biophysica Acta (BBA) - General Subjects
G-quadruplex (G4) structures are key elements in the regulation of cancer cell proliferation and their targeting is deemed to be… Continue reading Tandem application of ligand-based virtual screening and G4-OAS assay to identify novel G-quadruplex-targeting chemotypes
2017 / Tetrahedron
A novel Schiff base ligand, 2-(benzothiazol-2-yl-hydrazono)-1,2-diphenyl-ethanone (LH), has been synthesized out of the 1:1 condensation of benzil and 2-hydrazino benzothiazol… Continue reading Synthesis, characterization, structure, DNA binding aspects and molecular docking study of a novel Schiff base ligand and its bis(μ-chloro) bridged Cu(II) dimer
2017 / Biochimica et Biophysica Acta (BBA) - General Subjects
Fibroblast growth factor receptor 2 (FGFR2) is overexpressed in breast cancer tissues and cells, and has been shown to be… Continue reading Investigation of G-quadruplex formation in the FGFR2 promoter region and its transcriptional regulation by liensinine
2017 / Journal of Peptide Science
The development of mitochondria-targeting cell permeable vectors represents a promising therapeutic approach for several diseases, such as cancer and oxidative… Continue reading Development of poly(lactide-co-glycolide) nanoparticles functionalized with a mitochondria penetrating peptide
2017 / Protein Science
Thermophilic Hydrogenophilus thermoluteolus cytochrome c’ (PHCP) exhibits higher thermal stability than a mesophilic counterpart, Allochromatium vinosum cytochrome c’ (AVCP), which has a homo-dimeric structure and ligand-binding… Continue reading Structural and functional insights into thermally stable cytochrome c’ from a thermophile
2017 / Scientific Reports
PREP1 and PBX1 are homeodomain (HD) transcription factors that play crucial roles in embryonic development. Here, we present the first… Continue reading New Insights into Cooperative Binding of Homeodomain Transcription Factors PREP1 and PBX1 to DNA
2017 / Protein Expression and Purification
Marine luciferases are regularly employed as useful reporter molecules across a range of various applications. However, attempts to transition expression… Continue reading Expression of a soluble truncated Vargula luciferase in Escherichia coli
2017 / Journal of Applied Polymer Science
Novel optically active and racemic poly(N-propargylamides) bearing tyrosine pendants (LPT, DPT, and RPT) were synthesized and characterized. The polymers possessed… Continue reading Optically active tyrosine-containing poly(N-propargylamides): Synthesis, helical conformation, and infrared emissivity study
2017 / JACS
Applications of graphene have extended into areas of nanobio-technology such as nanobio-medicine, nanobio-sensing, as well as nanoelectronics with biomolecules. These… Continue reading Molecular Interactions between Graphene and Biological Molecules
2017 / PNAS
Apolipoprotein E (apoE) plays a critical role in cholesterol transport in both peripheral circulation and brain. Human apoE is a… Continue reading Helical structure, stability, and dynamics in human apolipoprotein E3 and E4 by hydrogen exchange and mass spectrometry
