Found 9617 Results / Page 371 of 481
2016 / Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
Nucleophosmin (NPM1) is a multifunctional protein involved in a variety of biological processes including the pathogenesis of several human malignancies… Continue reading Insights into amyloid-like aggregation of H2 region of the C-terminal domain of nucleophosmin
2016 / Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
A major intracellular calcium (Ca2 +) uptake pathway in both excitable and non-excitable eukaryotic cells is store-operated Ca2 + entry (SOCE). SOCE is… Continue reading Structural perturbations induced by Asn131 and Asn171 glycosylation converge within the EFSAM core and enhance stromal interaction molecule-1 mediated store operated calcium entry
2016 / Chinese Chemical Letters
Phytochemical investigation on the whole plant of Inula cappa led to the isolation of two new germacrane-type sesquiterpene lactones, ineupatolides D and… Continue reading Cytotoxic germacrane-type sesquiterpene lactones from the whole plant of Inula cappa
2016 / Biochemistry and Biophysics Reports
Unnatural glycolipids possessing the diyne moiety in their acyl groups were successfully biosynthesized in the green sulfur photosynthetic bacterium Chlorobaculum (Cba.) tepidum by cultivation… Continue reading Biosynthesis of unnatural glycolipids possessing diyne moiety in the acyl chain in the green sulfur photosynthetic bacterium Chlorobaculum tepidum grown by supplementation of 10,12-heptadecadiynic acid
2016 / Proteins: Structure, Function, and Bioinformatics
c-Myc is a basic Helix-Loop-Helix Leucine Zipper (b-HLH-LZ) transcription factor deregulated in the majority of human cancers. As a heterodimer… Continue reading Miz-1 and Max Compete to Engage c-Myc: Implication for the Mechanism of Inhibition of c-Myc Transcriptional Activity by Miz-1
2016 / Chemistry and Physics of Lipids
The mutated recombinant kinase domain of human fibroblast growth factor receptor 2b (hFGFR2b) is overexpressed and purified, and its structural… Continue reading Structural characterization of recombinant human fibroblast growth factor receptor 2b kinase domain upon interaction with omega fatty acids
2016 / Journal of Inorganic Biochemistry
Seven ferrocenyl naphthalene diimide (FND) ligands were synthesized. Each had a higher affinity for tetraplex DNA than for either single-… Continue reading Ferrocenyl naphthalene diimides as tetraplex DNA binders
2016 / Applied Microbiology and Biotechnology
Several polyene macrolides are potent antifungal agents that have severe side effects. Increased glycosylation of these compounds can improve water… Continue reading Engineered biosynthesis and characterisation of disaccharide-modified 8-deoxyamphoteronolides
2016 / European Journal of Organic Chemistry
The synthesis and investigation of molecular artificial motors have been subject to massive developments over the last years. One challenge… Continue reading A Light- and Electricity-Driven Molecular Pushing Motor
2017 / Protein Expression and Purification
Human interleukin-3 (hIL-3) is a pleiotropic cytokine that stimulates the differentiation and proliferation of multipotent hematopoietic cells thus making it… Continue reading High-level expression and efficient refolding of therapeutically important recombinant human Interleukin-3 (hIL-3) in E. coli
2017 / International Journal of Biological Macromolecules
Aqueous solutions of reline and glyceline, the most common deep eutectic solvents, were used as a medium for Catalase reaction.… Continue reading The effect of deep eutectic solvents on catalytic function and structure of bovine liver catalase
2016 / Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
Glycosylation of DNA, proteins, lipids, etc. by reducing sugars, can lead to the formation of advanced glycation end products (AGEs).… Continue reading Fructosylation induced structural changes in mammalian DNA examined by biophysical techniques
2016 / Journal of Industrial and Engineering Chemistry
We report a facile two-step strategy for grafting lanthanide complexes onto the surface of nanocrystalline cellulose-templated mesoporous silica films to… Continue reading Fabrication of free-standing fluorescent mesoporous silica films for detection of nitrobenzene
2017 / Fitoterapia
Uncariols A (1) and B (2), two new phenylpropanoid-substituted flavan-3-ols, and (±)-uncariols C (3a/3b) and D (4a/4b), two pairs of… Continue reading New phenylpropanoid-substituted flavan-3-ols and flavonols from the leaves of Uncaria rhynchophylla
2017 / Redox Biology
Infection with oncogenic human papillomavirus induces deregulation of cellular redox homeostasis. Virus replication and papillomavirus-induced cell transformation require persistent expression… Continue reading Degenerate cysteine patterns mediate two redox sensing mechanisms in the papillomavirus E7 oncoprotein
2017 / Archives of Biochemistry and Biophysics
Heat shock protein 70 kDa (Hsp70) is a conserved molecular chaperone family involved in several functions related to protein homeostasis. In… Continue reading Structural and functional studies of the Leishmania braziliensismitochondrial Hsp70: Similarities and dissimilarities to human orthologues
2017 / International Journal of Biological Macromolecules
In this study, we report the protective effects of linolenic acid towards the formation of early (HbA1c) and advanced glycation… Continue reading Linolenic acid prevents early and advanced glycation end-products (AGEs) modification of albumin
2016 / Journal of Solid State Chemistry
The reactions of Zn(NO3)2∙6H2O with mixed ligands of 5-amino-tetrazole (Hatz) and l,2,4,5-benzenetetracarboxylic acid (H4btec) under hydro(solvo)thermal conditions, gave two three-dimensional… Continue reading Two Zinc(II) metal-organic frameworks with mixed ligands of 5-amino-tetrazolate and l,2,4,5-benzenetetracarboxylate: synthesis, structural diversity and photoluminescent properties ☆
2016 / Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
Mutations in the C-terminus of human erythroid 5-aminolevulinate synthase (hALAS2), a pyridoxal 5′-phosphate (PLP)-dependent enzyme, are associated with two different… Continue reading Isoniazid inhibits human erythroid 5-aminolevulinate synthase: Molecular mechanism and tolerance study with four X-linked protoporphyria patients
2016 / Structure
Mycobacterium tuberculosis harbors proteasomes that recruit substrates for degradation through an ubiquitin-like modification pathway. Recently, a non-ATPase activator termed Bpa (bacterial proteasome… Continue reading Structural Analysis of the Bacterial Proteasome Activator Bpa in Complex with the 20S Proteasome
