Leah Pandiscia, PhD
July 28, 2017
The role of antibody structure (conformation) in solution rheology is probed. It is demonstrated here that pH-dependent changes in the… Continue reading Both Reversible Self-Association and Structural Changes Underpin Molecular Viscoelasticity of mAb Solutions
Leah Pandiscia, PhD
July 28, 2017
A C2-symmetric binaphthyl-based luminophore connected to two luminescent pyrene pendants was designed to express cryptochirality, as demonstrated by the ultraweak circular… Continue reading Cryptochiral binaphthyl–bipyrene luminophores linked with alkylene esters: intense circularly polarised luminescence, but ultraweak circular dichroism
Leah Pandiscia, PhD
July 28, 2017
Citrus tristeza virus (CTV), a positive-strand RNA virus within the family of Closteroviridae, is distributed worldwide and causes one of… Continue reading Rapid pre-symptomatic recognition of tristeza viral RNA by a novel fluorescent self-dimerized DNA–silver nanocluster probe
Leah Pandiscia, PhD
July 28, 2017
To fully understand the biochemical mechanisms of (−)-epigallocatechin gallate (EGCG) against obesity disease, the molecular inhibitory effects of EGCG on… Continue reading Advancing insights on the anti-obesity biochemical mechanism of (−)-epigallocatechin gallate (EGCG) by inhibiting α-amylase activity
Leah Pandiscia, PhD
July 28, 2017
In this work, we integrate DNA computing at the nanoscale on the basis of the self-assembly of single stranded polyA-DNA… Continue reading Effective construction of AuNPs-DNA system for the implementation of various advanced logic gates
Leah Pandiscia, PhD
July 28, 2017
A nucleoside analogue comprising the ligand 1H-imidazo[4,5-f][1,10]phenanthroline (P) was applied to develop a molecular beacon capable of discriminating the canonical… Continue reading A metal-mediated base pair that discriminates between the canonical pyrimidine nucleobases
Leah Pandiscia, PhD
July 28, 2017
Four new Ru(II) polypyridyl complexes that contain an extended aromatic moiety derived from pyrazino[2,3-h]dipyrido[3,2-a:2′,3′-c]phenazine and either 1,10-phenanthroline (phen) or 1,4,5,8-tetraazaphenanthrene… Continue reading Luminescent ruthenium polypyridyl complexes with extended ‘dppz’ like ligands as DNA targeting binders and cellular agents
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
In this paper, we report two chiral sheet-like structures based on amino acid functionalized polyoxomolybdates, [Na(H2O)2][Na(H2O)3][MMo6O21(O2CCH2NH3)3]∙2.5H2O (M=Te 1, Se 2;… Continue reading Chiral polyoxomolybdate-based hybrid compounds obtained by spontaneous resolution: syntheses, structures and nonlinear optical properties
Leah Pandiscia, PhD
July 28, 2017
Hemopressin is a neuropeptide, derived from the degradation of the α(1)-chain of hemoglobin, and possesses several pharmacologic properties, such as… Continue reading DOES hemopressin bind metal ions in vivo?
Leah Pandiscia, PhD
July 28, 2017
Bile salt-mediated conformational modification of hemoglobin (Hb) was examined at three different pHs i.e., 3.2, 7.4 and 9.0. The added bile… Continue reading Contrasting effects of pH on the modulation of the structural integrity of hemoglobin induced by sodium deoxycholate
Leah Pandiscia, PhD
July 28, 2017
Metandienone (MET) is an exogenous anabolic androgenic steroid. The interaction between MET and human serum albumin (HSA) was investigated by… Continue reading The binding properties of metandienone and human serum albumin by comparing with other five similar compounds
Leah Pandiscia, PhD
July 28, 2017
Many biochemical pathways involving nerve growth factor (NGF), a neurotrophin with copper(II) binding abilities, are regulated by the ubiquitin (Ub)… Continue reading Ubiquitin Associates with N-Terminal Domain of Nerve Growth Factor: The Role of Copper(II) Ions
Leah Pandiscia, PhD
July 28, 2017
To determine whether non-thermal effect exist during the process of enzyme inactivation by microwave radiation, the conformation and activity of… Continue reading Evaluation of the possible non-thermal effect of microwave radiation on the inactivation of wheat germ lipase
Leah Pandiscia, PhD
July 28, 2017
Light chain (AL) amyloidosis is a systemic disease characterized by the formation of immunoglobulin light-chain fibrils in critical organs of… Continue reading Solid-state NMR chemical shift assignments for AL-09 VL immunoglobulin light chain fibrils
Leah Pandiscia, PhD
July 28, 2017
We used protein fusion technology to transplant the Cys3–Cys4 loop of HGFI (a class I hydrophobin from Grifola frondosa) into a… Continue reading Investigation of the relationship between the rodlet formation and Cys3–Cys4 loop of the HGFI hydrophobin
Leah Pandiscia, PhD
July 28, 2017
The methylotrophic yeast Pichia pastoris has been used extensively for expressing recombinant proteins because it combines the ease of genetic manipulation, the… Continue reading Structural characterization of the α-mating factor prepro-peptide for secretion of recombinant proteins in Pichia pastoris
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Extracts containing cationic proteins from Moringa oleifera seeds are used to reduce drinking water turbidity in developing regions where the plant grows.… Continue reading Comparative coagulation performance study of Moringa oleifera cationic protein fractions with varying water hardness
Leah Pandiscia, PhD
July 28, 2017
