Found 9617 Results / Page 375 of 481
2016 / Applied Materials & Interfaces
Deposition of amyloid fibers has been a common pathological event in number of neurodegenerations such as Alzheimer’sdisease, Parkinson disease, Prion… Continue reading Nano Zinc Oxide Inhibits Fibrillar Growth and Suppresses Cellular Toxicity of Lysozyme Amyloid
2016 / Biophysical Journal
Protein-side-chain protonation, coupled to conformational rearrangements, is one way of regulating physiological function caused by changes in protein environment. Specifically,… Continue reading The pH-Dependent Trigger in Diphtheria Toxin T Domain Comes with a Safety Latch
2016 / Langmuir
With the advent of newer luminescent nanoparticles (NPs) for bioimaging applications, their complex interactions with the individual biomolecules need to… Continue reading Insights into the Thermodynamics of Polymer Nanodot–Human Serum Albumin Association: A Spectroscopic and Calorimetric Approach
2017 / Developmental & Comparative Immunology
CrustinPm1 and crustinPm7 are the two most abundant isoforms of crustins identified from the hemocytes of the black tiger shrimp, Penaeus… Continue reading Characterization of molecular properties and regulatory pathways of CrustinPm1 and CrustinPm7 from the black tiger shrimp Penaeus monodon
2016 / Journal of Structural Biology
The Pfam PF04536 TPM_phosphatase family is a broadly conserved family of domains found across prokaryotes, plants and invertebrates. Despite having… Continue reading Structural and functional characterization of a cold adapted TPM-domain with ATPase/ADPase activity
2016 / Journal of Materials Chemistry B
In addition to intravenous injections (i.v.), topical dosing of doxorubicin hydrochloride (DOX) has also been the focus of cancer treatment… Continue reading Nano-rods of doxorubicin with poly(L-glutamic acid) as a carrier-free formulation for intratumoral cancer treatment
2016 / Langmuir
The gelation behavior of mixtures of sodium deoxycholate (NaDC) and glutathione (GSH) in water is investigated. The system exhibits a… Continue reading Hydrogels of Super-Long Helices to Synthesize Hybrid Ag-Helical Nanomaterials
2016 / Biochimie
Human lysozyme is homologous in the three-dimensional structure to hen lysozyme and the latter is commonly used to understand folding… Continue reading A Comparative Study of Fibrillation Kinetics of Two Homologous Proteins under Identical Solution Condition
2016 / Journal of Molecular Catalysis B: Enzymatic
This study aimed to improve the thermostability of endo-1,4-β-xylanase (afxynG1) from Aspergillus fumigatus RT-1 using error-prone PCR. Since the wild type enzyme has… Continue reading Thermostability enhancement of xylanase Aspergillus fumigatus RT-1
2016 / Journal of Photochemistry and Photobiology B: Biology
Formation of ruthenium(II) complexes of the type [RuH(CO)(PPh3)2(L)] (where L = N-Substituted 9-ethyl carbazole thiosemicarbazone ligands) has been described from the reactions… Continue reading Ru(II) carbazole thiosemicarbazone complexes with four membered chelate ring: Synthesis, molecular structures and evaluation of biological activities
2016 / Dyes and Pigments
We have studied the intra- and inter-molecular chirogenesis events on a family of chiral bisporphyrin hosts H1-H3. The three pairs of… Continue reading Intramolecular chirality induction and intermolecular chirality modulation in BINOL bridged bisporphyrin hosts
2016 / Phytochemistry
Cholinesterase inhibition is one of the most treatment strategies against Alzheimer’s disease (AD) where metal accumulation is also strongly associated… Continue reading Selective in vitro and in silico butyrylcholinesterase inhibitory activity of diterpenes and rosmarinic acid isolated from Perovskia atriplicifolia Benth. and Salvia glutinosa L.
2016 / Catalysts
A heme-dependent peroxidase (HDP) catalyzes the ortho-hydroxylation of l-tyrosine to l-3,4-dihydroxyphenylalanine (l-DOPA) in the presence of hydrogen peroxide. l-DOPA can be used for… Continue reading Enhancing the Enzymatic Activity of a Heme-Dependent Peroxidase through Genetic Modification
2016 / ChemBioChem
Here, we present the design, synthesis and characterization of a novel photocaged glutamine derivative on the side-chain of glutamine and… Continue reading A novel caged-glutamine derivative as a tool to control the assembly of glutamine-containing amyloidogenic peptides
2016 / ChemBioChem
Acyclic serinol derivatives are useful scaffolds for tethering dyes within DNA duplexes. Here we synthesized an inverse L-threoninol (iL-threoninol) scaffold… Continue reading Effect of Methyl Group on Acyclic Serinol Scaffold for Tethering Dyes on DNA Duplex stability
2016 / Journal of Agricultural and Food Chemistry
Two new benzophenones (1 and 2) and four new xanthones (4–6 and 17) together with 24 known compounds (3, 7–16… Continue reading New Benzophenones and Xanthones from Cratoxylum sumatranum ssp. neriifolium and Their Antibacterial and Antioxidant Activities
2016 / Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
Type VII collagen is the major constituent of anchoring fibrils. It has a central collagenous domain that is surrounded by… Continue reading A type VII collagen subdomain mutant is thermolabile and shows enhanced proteolytic degradability – implications for the pathogenesis of recessive dystrophic epidermolysis bullosa?
2016 / The Journal of Biological Chemistry
The facultative intracellular pathogen Listeria monocytogenes causes listeriosis, a rare but life-threatening disease. Host cell entry begins with activation of… Continue reading MET-activating Residues in the B-repeat of the Listeria monocytogenes Invasion Protein InlB
2016 / Molecules
Amphibian skin secretions are unique sources of bioactive molecules, particularly bioactive peptides. In this study, the skin secretion of the… Continue reading A Combined Molecular Cloning and Mass Spectrometric Method to Identify, Characterize, and Design Frenatin Peptides from the Skin Secretion of Litoria infrafrenata
2016 / Molecules
Penicitroamide (1), a new metabolite with a new framework, was isolated from the ethyl acetate extract of the PDB (Potato… Continue reading Penicitroamide, an Antimicrobial Metabolite with High Carbonylization from the Endophytic Fungus Penicillium sp. (NO. 24)
