Few-atom silver nanoclusters (AgNCs) can exhibit strong fluorescence; however, they require ligands to prevent aggregation into larger nanoparticles. Fluorescent AgNCs… Continue reading Peptide-Stabilized, Fluorescent Silver Nanoclusters: Solid-Phase Synthesis and Screening
Leah Pandiscia, PhD
July 28, 2017
Oligodeoxynucleotides (ODNs) containing 2-N-tert-butylaminoxyl-2′-deoxyadenosine (A*) residues were synthesized to allow accurate monitoring of adenine motion by EPR spectroscopy through the… Continue reading Synthesis and Electron Paramagnetic Resonance Studies of Oligodeoxynucleotides Containing 2-N-tert-Butylaminoxyl-2′-deoxyadenosines
Leah Pandiscia, PhD
July 28, 2017
Facile synthesis of white-emitting, protein-based, metal-free, stable, nontoxic, and pH sensitive, advanced functional nanoparticles (GlowDots), as alternatives to quantum dots,… Continue reading White-Emitting Protein Nanoparticles for Cell-Entry and pH Sensing
Leah Pandiscia, PhD
July 28, 2017
In our investigation, most Shihu (石斛; Japanese name, Sekkoku) in current Japanese commercial crude drugs were from Flickingeria xantholeuca (Orchidaceae). As the index compounds, three… Continue reading Evaluation of the chemical quality of Sekkoku in current Japanese commercial crude drugs: constituents of Flickingeria xantholeuca (Rchb. f.) A.D. Hawkes
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Three novel 2,3-diaryl indone derivatives, ascomindones A−C (1−3), and two new isobenzofuran derivatives, ascomfurans A (4) and B (5), together… Continue reading Antioxidative Polyketones from the Mangrove-Derived Fungus Ascomycota sp. SK2YWS-L
Leah Pandiscia, PhD
July 28, 2017
Cathelicidins, a major family of vertebrate antimicrobial peptides (AMPs), have a recognized role in the first line of defense against… Continue reading Antimicrobial and host cell-directed activities of Gly/Ser-rich peptides from salmonid cathelicidins
Leah Pandiscia, PhD
July 28, 2017
Four new lignans, (7′R,8′S)-4,4′-Dimethoxy-strebluslignanol (1), 3′-Hydroxy-isostrebluslignaldehyde (2), 3,3′-Methylene-bis(4-hydroxybenzaldehyde) (3), and 4-Methoxy-isomagnaldehyde (4), and six known lignans (5–10), were isolated from… Continue reading Antimicrobial lignans derived from the roots of Streblus asper
Leah Pandiscia, PhD
July 28, 2017
Sphingomyelinases D have only been identified in arachnid venoms, Corynebacteria, Arcanobacterium, Photobacterium and in the fungi Aspergillus and Coccidioides. The arachnid and bacterial enzymes share… Continue reading Bacterial and Arachnid Sphingomyelinases D: Comparison of Biophysical and Pathological Activities†
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
The study shows that RADA-F6 peptide with pH-responsive self-assembling nature can be effectively used as a drug delivery system for… Continue reading Self-assembling peptide nanofibers containing phenylalanine for the controlled release of 5-fluorouracil
Leah Pandiscia, PhD
July 28, 2017
Cytotoxicity of the Amyloid beta (Aβ) peptide, implicated in pathogenesis of Alzheimer’s disease (AD), can be enhanced by its post-translational… Continue reading Glycation Induces Conformational Changes in Amyloid-β Peptide and Enhances its Aggregation Propensity: Molecular Insights
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Protein and peptide aggregation/fibrillation is reported to be responsible for several neurological disorders. Fibrillation of the amyloid β-peptide fragment (25–35)… Continue reading Hydropathy: the controlling factor behind the inhibition of Aβ fibrillation by graphene oxide
Leah Pandiscia, PhD
July 28, 2017
Near-infrared fluorescent proteins (NIR FPs) engineered from bacterial phytochromes and their mutants with different location of Cys residues, which able… Continue reading Stabilization of structure in near-infrared fluorescent proteins by binding of biliverdin chromophore
Leah Pandiscia, PhD
July 28, 2017
In this paper, the contribution of chitin nanowhiskers (CHNW) to the enzymatic activity and antimicrobial activity of lysozyme adsorbed on… Continue reading Enhanced antibacterial activity of lysozyme immobilized on chitin nanowhiskers
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017