Found 9617 Results / Page 38 of 481
2022 / Communications Biology
Evolution of proteins is constrained by their structure and function. While there is a consensus that the plasticity of intrinsically… Continue reading The dynamic properties of a nuclear coactivator binding domain are evolutionarily conserved
2022 / Scientific reports
Numerous studies have shown a strong correlation between the number of neurofibrillary tangles of the tau protein and Alzheimer’s disease… Continue reading Rational design and synthesis of a novel BODIPY-based probe for selective imaging of tau tangles in human iPSC-derived cortical neurons
2022 / Nature Communications
In the long history of traditional Chinese medicine, single herbs and complex formulas have been suggested to increase lifespan. However,… Continue reading The flavonoid corylin exhibits lifespan extension properties in mouse
2022 / Nature Communications
The creation of low-dimensional heterostructures for intelligent devices is a challenging research topic; however, macro- and atomic-scale connections in one-dimensional… Continue reading Macro- and atomic-scale observations of a one-dimensional heterojunction in a nickel and palladium nanowire complex
2022 / Nature Communications
Borophene has been recently proposed as a next-generation two-dimensional material with promising electronic and optical properties. However, its instability has… Continue reading Liquid crystalline 2D borophene oxide for inorganic optical devices
2022 / Nature Communications
Ascertaining the function of in-plane intrinsic defects and edge atoms is necessary for developing efficient low-dimensional photocatalysts. We report the… Continue reading Atomistic insights into highly active reconstructed edges of monolayer 2H-WSe2 photocatalyst
2022 / Scientific Reports
Biogenic amorphous calcium carbonate (ACC) is typically metastable and can rapidly transform through aging, dehydration, and/or heating to crystalline calcium… Continue reading An exceptionally stable and widespread hydrated amorphous calcium carbonate precipitated by the dog vomit slime mold Fuligo septica (Myxogastria)
2022 / Communications Biology
The role of dimer formation for the onset of catalytic activity of SARS-CoV-2 main protease (MProWT) was assessed using a… Continue reading Modulation of the monomer-dimer equilibrium and catalytic activity of SARS-CoV-2 main protease by a transition-state analog inhibitor
2022 / Scientific Reports
Parkinson’s disease (PD) is a neurodegenerative condition featured by motor dysfunction, death of midbrain dopaminergic neurons and accumulation of α-synuclein… Continue reading Transcellular propagation of fibrillar α-synuclein from enteroendocrine to neuronal cells requires cell-to-cell contact and is Rab35-dependent
2022 / npj Clean Water
Reverse electrodialysis (RED) generates electricity from a mixture of seawater and river water. Herein, patterned membranes consisting of ultra-thin pore-filling… Continue reading Fouling behavior of wavy-patterned pore-filling membranes in reverse electrodialysis under natural seawater and sewage effluents
2022 / Biotechnology Journal
Broadly used in biocatalysis as acyl acceptors or (co)-solvents, short-chain alcohols often cause irreversible loss of enzyme activity. Understanding the… Continue reading Short-chain alcohols inactivate an immobilized industrial lipase through two different mechanisms
2022 / NANO MICRO small
Small scratches and abrasion cause damage to packaging coatings. Albeit often invisible to the human eye, such small defects in… Continue reading Supraparticles with a Mechanically Triggerable Color-Change-Effect to Equip Coatings with the Ability to Report Damage
2022 / Macro Molecular Materials and Engineering
Lately, environmentally benign packaging materials with biodegradability, flexibility, and high barrier properties are sought after as a substitute for conventional… Continue reading High Barrier, Biodegradable Nanocomposite Films Based on Clay-Coated and Chemically Modified Gum Kondagogu
2022 / Nature Communications
The task of protein sequence design is central to nearly all rational protein engineering problems, and enormous effort has gone… Continue reading Protein sequence design with a learned potential
2022 / NPG Asia Materials
Spin tunability by circularly polarized photons occurs in an unconnected method, providing more spaces to design memory devices. Here, by… Continue reading Control of the conversion between circularly polarized photons and spin by introducing chiral orbit in organic complexes
2022 / FEBS Letters
Calmodulin is a conserved calcium signalling protein that regulates a wide range of cellular functions. Amino-terminal acetylation is a ubiquitous… Continue reading Acetylation stabilises calmodulin-regulated calcium signalling
2022 / Scientific Reports
Plants have served for centuries as sources of compounds useful for human health such as antioxidant, anti-diabetic and antitumor agents.… Continue reading Hippophae rhamnoides L. leaf and twig extracts as rich sources of nutrients and bioactive compounds with antioxidant activity
2022 / Macro Moldecular chemistry and physics
Melanins are a class of biopolymers that are widespread in nature, with diverse origins, compositions, and functions, and their chemical… Continue reading The Polymerization of Homogentisic Acid In Vitro as a Model for Pyomelanin Formation
2022 / Macro Moldecular materials and engineering
Stereolithography is a lithography-based additive manufacturing technology, in which liquid photoreactive resins are solidified by ultraviolet or visible light in… Continue reading Novel Thiol-Ene Photo Resins for Stereolithography with Enhanced Mechanical and Optical Properties
2022 / Science of Food and Agriculture
There is increasing consumer demand for olive oil to be traceable. However, genotype, environmental factors, and stage of maturity, all… Continue reading Identifying volatile and non-volatile organic compounds to discriminate cultivar, growth location, and stage of ripening in olive fruits and oils
