Found 9617 Results / Page 386 of 481
2016 / RSC Advances
The aromatic 5/6 ring overlaps at the interface of 5′-5′ stacked dimers formed by two parallel G-quadruplexes have been demonstrated… Continue reading Correlations between Fluorescence Emission and Base Stacks of Nucleic Acid G-quadruplexes
2016 / Toxicological Sciences
Triplex forming oligonucleotides (TFOs) bind in the major groove of DNA duplex in a sequence-specific manner imparted by Hoogsteen hydrogen… Continue reading The lack of mutagenic potential of a guanine-rich triplex forming oligonucleotide in physiological conditions
2016 / International Journal of Biological Macromolecules
Vibrio harveyi chitinase A (VhChiA) is a GH-18 glycosyl hydrolase with a structure containing three distinct domains: i) the N-terminal chitin-binding domain;… Continue reading The Chitin-Binding Domain of a GH-18 Chitinase from Vibrio harveyi is Crucial for Chitin-Chitinase Interactions
2016 / PLoS ONE
The TNF-α biological inhibitors have significantly improved the clinical outcomes of many autoimmune diseases, in particular rheumatoid arthritis. However, the… Continue reading A Rationally Designed TNF-α Epitope-Scaffold Immunogen Induces Sustained Antibody Response and Alleviates Collagen-Induced Arthritis in Mice
2016 / Scientific Reports
Aptamers for whole cell detection are selected mostly by the Cell-SELEX procedure. Alternatively, the use of specific cell surface epitopes… Continue reading G-quadruplex aptamer targeting Protein A and its capability to detect Staphylococcus aureusdemonstrated by ELONA
2016 / RSC Advances
The present study demonstrates the synthesis of a new pyrene based water soluble fluorescent probe and its interaction with Calf-thymus… Continue reading Interaction of a synthesized pyrene based fluorescent probe with CT-DNA: spectroscopic, thermodynamic and molecular modeling studies
2016 / RSC Advances
A series of lanthanide (Ln) ion-containing enantiomeric crystalline compounds of [Ln(α-PW11O39)2]11− polyanions was successfully isolated by using proline (Pro) as a… Continue reading On chirality induction in the crystalline solid-containing sandwich-type [Ln(α-PW11O39)2]11−polyoxotungstate and proline
2017 / Food Chemistry
A β-Lactoglobulin fraction (r-βLg) was isolated from whey hydrolysates produced with cardosins from Cynara cardunculus. The impact of the hydrolysis process… Continue reading Influence of pH on viscoelastic properties of heat-induced gels obtained with a β-Lactoglobulin fraction isolated from bovine milk whey hydrolysates
2016 / Biophysical Chemistry
Amylin is a pancreatic peptide hormone co-secreted along with insulin by the β-cells. It is found in amyloid deposits in… Continue reading Amyloidogenesis of the amylin analogue pramlintide
2016 / Journal of Photochemistry and Photobiology B: Biology
The binding interaction between a typical angiotensin-converting enzyme inhibitor (ACEI), ramipril, and a transport protein, bovine serum albumin (BSA), was… Continue reading Binding interaction of ramipril with bovine serum albumin (BSA): Insights from multi-spectroscopy and molecular docking methods
2016 / Phytochemistry
Four meroterpenoids, 1-hydroxychevalone C, 1-acetoxychevalone C, 1,11-dihydroxychevalone C, and 11-hydroxychevalone C and two ester epimers, 2S,4S-spinosate and 2S,4R-spinosate, together with… Continue reading Chevalone C analogues and globoscinic acid derivatives from the fungus Neosartorya spinosa KKU-1NK1
2016 / Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
The hallmarks of Parkinson’s disease and other synucleinopathies, Tubulin Polymerization Promoting Protein (TPPP/p25) and α-synuclein (SYN) have two key features:… Continue reading Challenging Drug Target for Parkinson’s Disease: pathological complex of the chameleon TPPP/p25 and alpha-synuclein proteins
2016 / International Dairy Journal
In-vitro digestion behaviour of iron saturated (holo)-, native- and iron depleted (apo)- bovine lactoferrin (LF) was studied in simulated oral,… Continue reading Mild thermal treatment and in-vitro digestion of three forms of bovine lactoferrin: Effects on functional properties
2016 / Journal of Molecular Liquids
The properties of DNA in ionic liquids (ILs) have been well studied. However, it is not widely known about the… Continue reading Binding energy and biophysical properties of ionic liquid-DNA complex: Understanding the role of hydrophobic interactions
2017 / Protein Expression and Purification
Olfactory receptors (ORs) play a crucial role in detecting the odorant molecules present in the surrounding environment. These receptors, which… Continue reading Biophysical and functional characterization of the human olfactory receptor OR1A1 expressed in a mammalian inducible cell line
2016 / Biochimica et Biophysica Acta (BBA) - General Subjects
GabR is a transcriptional regulator belonging to the MocR/GabR family, characterized by a N-terminal wHTH DNA-binding domain and a C-terminal… Continue reading Study of DNA binding and bending by Bacillus subtilis GabR, a PLP-dependent transcription factor
2016 / Food Hydrocolloids
Dynamic light-scattering (DLS), fluorescence spectroscopy (FS) and circular dichroism (CD) techniques were applied to study the influence of alcohol on… Continue reading Secondary structure and colloidal stability of beta-casein in microheterogeneous water-ethanol solutions
2016 / Journal of Inorganic Biochemistry
Topologies of G-quadruplexes depend on oligonucleotide sequences and on environmental factors, and the diversity of G-quadruplex topologies complicates investigation of… Continue reading Effects of metal ions and cosolutes on G-quadruplex topology
2016 / Sensors and Actuators B: Chemical
Bovine serum albumin (BSA) and glutathione (GSH) have been used to prepare gold nanoclusters (BSA/GSH-Au NCs) with excitation/emission wavelengths of… Continue reading Glutathione assisted preparation of gold nanoclusters using minimum amount of protein
2016 / Archives of Biochemistry and Biophysics
In many neurodegenerative diseases, formation of protein fibrillar aggregates has been observed as a major pathological change. Neurofibrillary tangles, mainly… Continue reading Appraisal of role of the polyanionic inducer length on amyloid formation by 412-residue 1N4R Tau protein: A comparative study
