Carlos Morillo
November 1, 2022
Protein lysine methyltransferases have important regulatory functions in cells, but mechanisms determining their activity and specificity are incompletely understood. Naturally, …
Continue reading “Mechanistic basis of the increased methylation activity of the SETD2 protein lysine methyltransferase towards a designed super-substrate peptide”
Carlos Morillo
November 1, 2022
Nanocolloids that are cumulatively referred to as nanocarbons, attracted significant attention during the last decade because of facile synthesis methods, …
Continue reading “Hydrothermal synthesis of chiral carbon dots”
Carlos Morillo
November 1, 2022
The exploration of stable and high-mobility semiconductors that can be grown over a large area using cost-effective methods continues to …
Continue reading “Evaporated nanometer chalcogenide films for scalable high-performance complementary electronics”
Carlos Morillo
November 1, 2022
Chemical investigation of Retama sphaerocarpa collected in Algeria resulted in the isolation of two megastigmane glucosides, compounds 1 and 2, …
Continue reading “First Occurrence of Megastigmane Glucosides in a Plant of Retama Genus”
Carlos Morillo
October 19, 2022
For microscale 4D photoresponsive actuators, light is crucial in two ways. First, the underlying additive manufacturing techniques rely on photopolymerization …
Continue reading “A Facile Approach for 4D Microprinting of Multi-Photoresponsive Actuators”
Carlos Morillo
October 19, 2022
Carlos Morillo
October 19, 2022
Low-density porous aramid films using inexpensive and widely available polymers as porosity promoters, that is, polyvinyl alcohol (PVA), poly(2-ethyl-2-oxazoline) (PEOx), …
Continue reading “Preparation of low-density high-performance porous aramid films using porosity promoter polymers”
Carlos Morillo
October 19, 2022
We report on the triplet sensitization of the intramolecular Photo-Dehydro-Diels-Alder (PDDA) reaction of two diaryl suberates bearing methyl propiolate chromophors. …
Continue reading “Triplet Sensitized Photo-Dehydro-Diels-Alder Reaction”
Carlos Morillo
October 19, 2022
Chinese Hamster Ovary cells (CHO) have become the most common workhorse for the commercial production of therapeutic proteins, as well …
Continue reading “Optimized rapid production of recombinant secreted proteins in CHO cells grown in suspension: The case of RBD”
Carlos Morillo
October 19, 2022
Chiral carbon nanoparticles (CNPs) represent a rapidly evolving area of research for optical and biomedical technologies. Similar to small molecules, …
Continue reading “Chiral chromatography and surface chirality of carbon nanoparticles”
Carlos Morillo
October 19, 2022
Date palm pits are highly available and inexpensive palm date by-products, representing a valuable source of natural antioxidants, particularly phenolic …
Continue reading “Active food packaging films from alginate and date palm pit extract: Physicochemical properties, antioxidant capacity, and stability”
Carlos Morillo
October 19, 2022
Calcium concentration must be finely tuned in all eukaryotic cells to ensure the correct performance of its signalling function. Neuronal …
Continue reading “The ataxia-linked E1081Q mutation affects the sub-plasma membrane Ca2+-microdomains by tuning PMCA3 activity”
Carlos Morillo
October 17, 2022
Dialysis-related amyloidosis (DRA), a serious complication among long-term hemodialysis patients, is caused by amyloid fibrils of β2-microglobulin (β2m). Although high …
Continue reading “Macromolecular crowding and supersaturation protect hemodialysis patients from the onset of dialysis-related amyloidosis”
Carlos Morillo
October 17, 2022
Humans and Acanthamoeba polyphaga mimivirus share numerous homologous genes, including collagens and collagen-modifying enzymes. To explore this homology, we performed …
Continue reading “Comparative genomic and biochemical analyses identify a collagen galactosylhydroxylysyl glucosyltransferase from Acanthamoeba polyphaga mimivirus”
Carlos Morillo
October 17, 2022
Carlos Morillo
October 17, 2022
Dynamic regulation of nucleic acid hybridization is fundamental for switchable nanostructures and controllable functionalities of nucleic acids in both material …
Continue reading “Controllable DNA hybridization by host–guest complexation-mediated ligand invasion”
Carlos Morillo
October 17, 2022
Plastic degradation by biological systems with re-utilization of the by-products could be a future solution to the global threat of …
Continue reading “Wax worm saliva and the enzymes therein are the key to polyethylene degradation by Galleria mellonella”
Carlos Morillo
October 17, 2022
Oxidative degradation of chitin, initiated by lytic polysaccharide monooxygenases (LPMOs), contributes to microbial bioconversion of crystalline chitin, the second most …
Continue reading “A pathway for chitin oxidation in marine bacteria”
Carlos Morillo
October 17, 2022
Antibodies, and antibody derivatives such as nanobodies, contain immunoglobulin-like (Ig) β-sandwich scaffolds which anchor the hypervariable antigen-binding loops and constitute …
Continue reading “De novo design of immunoglobulin-like domains”
Carlos Morillo
October 17, 2022