Found 9617 Results / Page 403 of 481
2016 / Peptides
Relaxin-3 or insulin-like peptide 7 (INSL7) is the most recently discovered relaxin/insulin-like family peptide. Mature relaxin-3 consists of an A… Continue reading Hydrocarbon stapled B chain analogues of relaxin-3 retain biological activity
2016 / Phytochemistry
The absolute configuration of phytotoxins inuloxins B and C, produced by Inula viscosa, and with potential herbicidal activity for the management… Continue reading Absolute configurations of phytotoxic inuloxins B and C based on experimental and computational analysis of chiroptical properties
2016 / Protein Expression and Purification
The Esx-1 cluster encodes a special secretion system that is important for granuloma formation and virulence when Mycobacterium tuberculosis infects the host.… Continue reading Expression, purification and characterization of Esx-1 secretion-associated protein EspL from Mycobacterium tuberculosis
2016 / Peptide Science
An antimicrobial triple-helical peptide, R3, was previously obtained from a collagen-like combinatorial peptide library. In the present research, based on structure–activity… Continue reading Structure–Activity Relationships and Action Mechanisms of Collagen-like Antimicrobial Peptides
2016 / PLoS ONE
Single-domain antibodies derived from the unique New Antigen Receptor found in sharks have numerous potential applications, ranging from diagnostic reagents… Continue reading Importance of Hypervariable Region 2 for Stability and Affinity of a Shark Single-Domain Antibody Specific for Ebola Virus Nucleoprotein
2016 / The Journal of Physical Chemistry C
Antimicrobial peptides (AMPs), due to their unique structure/function relationship, have great potential to be developed into novel diagnostic and therapeutic… Continue reading Orientation Determination of a Hybrid Peptide Immobilized on CVD-Based Reactive Polymer Surfaces
2016 / RSC Advances
The deposition of the islet amyloid polypeptide (IAPP) as insoluble amyloid fibrils in the pancreatic islets is associated with type… Continue reading Low generation anionic dendrimers modulate islet amyloid polypeptide self-assembly and inhibit pancreatic β-cell toxicity
2016 / Langmuir
Two chiral complexes (1-SDS, and 1-SDBS) were prepared via the ionic self-assembly of a chiral perylene diimide tecton with oppositely… Continue reading Chiral Perylene Materials by Ionic Self-Assembly
2016 / RSC Advances
The remarkable α-glucosidase inhibition exhibited by the acetone extract of rhizome of Ampelocissus indica (L.) and stem bark of Vateria… Continue reading Comparison of antidiabetic potential of (+) and (-)-Hopeaphenol, a pair of enantiomers isolated from Ampelocissus indica (L.) and Vateria indica Linn, with respect to inhibition of digestive enzymes and induction of glucose uptake in L6 myotubes
2016 / RSC Advances
Oligonucleotides carrying cationic peptides have been used to improve hybridization and cellular uptake of oligonucleotides. In this study, a series… Continue reading Cellular uptake studies of antisense oligonucleotides using G-quadruplex-nanostructures. The effect of cationic residue on the biophysical and biological properties
2016 / Physical Chemistry Chemical Physics
Octreotide and pasireotide are two cyclic somatostatin analogues with an important clinical use in the treatment and diagnosis of neuroendocrine… Continue reading From bulk to plasmonic nanoparticle surface: behavior of two potent therapeutic peptides, octreotide and pasireotide
2016 / The Journal of Physical Chemistry B
Amyloid fibrils are a large class of self-assembled protein aggregates that are formed from unstructured peptides and unfolded proteins. The… Continue reading Multimodal Spectroscopic Study of Amyloid Fibril Polymorphism
2016 / Journal of Bioscience and Bioengineering
The antimicrobial peptide AmyI-1-18 is a cationic α-helical octadecapeptide derived from α-amylase in rice (Oryza sativa L. japonica) that contains four cationic… Continue reading Antimicrobial activity against Porphyromonas gingivalis and mechanism of action of the cationic octadecapeptide AmyI-1-18 and its amino acid-substituted analogs
2016 / Journal of Photochemistry and Photobiology A: Chemistry
Zinc complexes of 3-hydroxymethyl-131-oxo-chlorins possessing various π-conjugatable substituents at the 8-position were prepared by chemical modification of naturally occurring chlorophyll-a.… Continue reading Visible and Near-Infrared Spectra of Chlorosomal Zinc Chlorin Self-Aggregates Dependent on Their Peripheral Substituents at the 8-Position
2016 / Journal of Structural Biology
Calpain-5 is a calcium-activated protease expressed in the retina. Mutations in calpain-5 cause autosomal dominant neovascular inflammatory vitreoretinopathy (ADNIV, OMIM#193235).… Continue reading Small-angle X-ray scattering of calpain-5 reveals a highly open conformation among calpains
2016 / Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
Structural comparisons of the cold adapted subtilase VPR and its thermophilic homologue, aqualysin I (AQUI) indicated the presence of additional… Continue reading A single mutation Gln142Lys doubles the catalytic activity of VPR, a cold adapted subtilisin-like serine proteinase
2016 / Journal of Molecular Catalysis B: Enzymatic
The transesterification reaction of series pyrimidine acyclonucleosides was carried out with lipase (EC 3.1.1.3) Amano PS from Burkholderia cepacia (BCL) as biocatalyst.… Continue reading Enantio- and diastereoselective acylation of prochiral hydroxyl group of pyrimidine acyclonucleosides
2016 / Biopolymers
Although the mechanism of action of antimicrobial peptides (AMPs) is not clear, they can interact electrostatically with the cell membranes… Continue reading Ocellatin-PT Antimicrobial Peptides: High Resolution Microscopy Studies in Antileishmania Models and Interactions with Mimetic Membrane Systems
2016 / Nucleic Acids Research
A newly designed cyclic bis-naphthyridine carbamate dimer CMBL4 with a limited conformational flexibility was synthesized and characterized. Absorption spectra revealed that two… Continue reading Cyclic mismatch binding ligand CMBL4 binds to the 5′-T-3′/5′-GG-3′ site by inducing the flipping out of thymine base
2016 / Scientific Reports
α-synuclein (α-syn) is the main component of Lewy bodies, which are neuropathological hallmarks of patients with Parkinson’s disease. As it… Continue reading A small-angle X-ray scattering study of alpha-synuclein from human red blood cells
