Found 9617 Results / Page 404 of 481
2016 / Chemistry - A European Journal
Two perylene diimide (PDI) enantiomers (d/l-PDI) incorporating the d/l-alanine moiety have been designed and synthesized. d/l-PDI in chloroform displays bright-yellow fluorescence that is… Continue reading Circularly Polarized Luminescence of Chiral Perylene Diimide Based Enantiomers Triggered by Supramolecular Self-Assembly
2016 / Analyst
A simple biosensing platform which involves the application of thermoresponsive hydrogels (p(NIPA-co-AA)) for detection of target DNA sequences is presented.… Continue reading Changes in the volume phase transition temperature of hydrogels for detection of the DNA hybridization process
2016 / Molecular Microbiology
FliS chaperone binds to flagellin FliC in the cytoplasm and transfers FliC to a sorting platform of the flagellar type… Continue reading Structural stability of flagellin subunit affects the rate of flagellin export in the absence of FliS chaperone
2016 / RSC Advances
Protein aggregation triggered by conformational changes is considered to be one of the major reasons for neuro-degenerative diseases like Alzheimer’s… Continue reading Micro-viscosity induced conformational transitions in poly-L-lysine
2016 / PLoS ONE
The application of poly(lactic acid) for sustained protein delivery is restricted by the harsh pH inside carriers. In this study,… Continue reading pH-Responsive Polyethylene Glycol Monomethyl Ether-ε-Polylysine-G-Poly (Lactic Acid)-Based Nanoparticles as Protein Delivery Systems
2016 / Journal of Nanoparticle Research
The application of zinc oxide (ZnO) nanoparticles in biomaterials has increased signifi- cantly in the recent years. Here, we aimed… Continue reading Synthesis and evaluation of the potential deleterious effects of ZnO nanomaterials (nanoneedles and nanoflowers) on blood components, including albumin, erythrocytes and human isolated primary neutrophils
2016 / The FEBS Journal
HtrA (DegP) from Escherichia coli, an important element of the extracytoplasmic protein quality-control system, is a member of the evolutionarily conserved… Continue reading The LD loop as an important structural element required for transmission of the allosteric signal in the HtrA (DegP) protease from Escherichia coli
2016 / Nanoscale
Traditional targeting nanoprobes suffer from the risks of partial loss of targeting activity and nanoparticles aggregation induced by post-modifications, ambiguous… Continue reading Green and Facile Synthesis of a Theranostic Nanoprobe with Intrinsic Biosafety and Targeting Ability
2016 / RSC Advances
The aim of this study was to design and prepare γ-Fe2O3@SiO2-zidovudine magnetic nanoparticles (MNPs) for magnetic guided drug targeting and… Continue reading Functionalization of γ-Fe2O3@SiO2 nanoparticles using the antiviral drug zidovudine: synthesis, characterization, in vitro cytotoxicity and DNA interaction studies
2016 / Antimicrobial Agents and Chemotherapy
Clinical isolates producing hybrid CTX-M β-lactamases, presumably due to recombination between the blaCTX-M-15 and blaCTX-M-14 elements, have emerged in recent years. Among the hybrid… Continue reading Comparative characterization of CTX-M-64 and CTX-M-14: insights into the structure and catalytic activity of the CTX-M class of enzymes
2016 / Enzyme and Microbial Technology
Uric acid, a side product of nucleotide metabolism, should be cleared from blood stream since its accumulation can cause cardiovascular… Continue reading Utilizing intein-mediated protein cleaving for purification of uricase, a multimeric enzyme
2016 / Biochemical and Biophysical Research Communications
Amylomaltase catalyzes intermolecular and intramolecular transglucosylation reactions to form linear and cyclic oligosaccharides, respectively. The aim of this work is… Continue reading Roles of N287 in catalysis and product formation of amylomaltase from Corynebacterium glutamicum
2016 / Journal of Molecular Structure
In the present study, interaction of a double-decker phthalocyanine with two G-quadruplex DNA, Tel 21 and cMYC, was investigated. To… Continue reading Circular dichroism spectroscopic investigation of double-decker phthalocyanine with G-Quadruplex as promising telomerase inhibitor
2016 / International Journal of Biological Macromolecules
A critical aggregation concentration of 0.30–0.50 mg/mL was previously obtained for type I collagen at 0.1 M acetic acid (AA). In the… Continue reading Changes in aggregation behavior of collagen molecules in solution with varying concentrations of acetic acid
2016 / International Journal of Biological Macromolecules
The changes of lysozyme structure during egg storage were investigated by Fluorescence spectroscopy, Circular Dichroism spectroscopy and Fourier Transform-Raman spectroscopy,… Continue reading The changes of secondary structures and properties of lysozyme along with the egg storage
2016 / Biophysical Journal
Point mutations in γ-cytoplasmic actin have been shown to result in autosomal-dominant, nonsyndromic, early-onset deafness. Two mutations at the same site,… Continue reading Two Deafness-Causing Actin Mutations (DFNA20/26) Have Allosteric Effects on the Actin Structure
2016 / Journal of Photochemistry and Photobiology B: Biology
C-myb proto-oncogene is a potential therapeutic target for some human solid tumors and leukemias. A long cytosine-rich sequence, which locates the… Continue reading The formation and characteristics of the i-motif structure within the promoter of the c-myb proto-oncogene
2016 / Biochimica et Biophysica Acta (BBA) - General Subjects
Molecular chaperones are a very special class of proteins that play essential roles in many cellular processes like folding, targeting… Continue reading Hsp60, amateur chaperone in amyloid-beta fibrillogenesis
2016 / Polymer Chemistry
Luminogenic materials with tunable fluorescence emission have attracted increasing interest due to their broad applications. Here, we develop a versatile… Continue reading Continuously-tunable fluorescent polypeptides through a polymer-assisted assembly strategy
2016 / Dalton Transactions
Two water-soluble thiosemicarbazone-proline (H2L1) and thiosemicarbazone-homoproline hybrids (H2L2) were synthesised. By reaction of H2L1 with NiCl2·6H2O, PdCl2 and CuCl2·2H2O in ethanol, the… Continue reading Structure–antiproliferative activity studies on L-proline- and homoproline-4-N-pyrrolidine-3-thiosemicarbazone hybrids and their nickel(II), palladium(II) and copper(II) complexes
