Found 9617 Results / Page 407 of 481

Characterizing the binding interaction between antimalarial artemether (AMT) and bovine serum albumin (BSA): Spectroscopic and molecular docking methods

2016 / Journal of Photochemistry and Photobiology B: Biology

Artemether (AMT), a peroxide sesquiterpenoides, has been widely used as an antimalarial for the treatment of multiple drug-resistant strains of… Continue reading Characterizing the binding interaction between antimalarial artemether (AMT) and bovine serum albumin (BSA): Spectroscopic and molecular docking methods

Leah Pandiscia, PhD

Directional modification of chrysin for exerting apoptosis and enhancing significantly anti-cancer effects of 10-hydroxy camptothecin

2016 / Biomedicine & Pharmacotherapy

Chrysin, one of natural flavonoid compounds, has recently been found to possess anti-inflammatory, antiallergic and anticancer properties. To increase its… Continue reading Directional modification of chrysin for exerting apoptosis and enhancing significantly anti-cancer effects of 10-hydroxy camptothecin

Leah Pandiscia, PhD

Fed-batch production of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) in soluble form in Escherichia coli and its purification and characterization

2016 / Protein Expression and Purification

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a promising anticancer agent. The aim of this study is to produce large… Continue reading Fed-batch production of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) in soluble form in Escherichia coli and its purification and characterization

Leah Pandiscia, PhD

Chiral molybdenum(VI) complexes with tridentate Schiff bases derived from S(+)-1-amino-2-propanol: Synthesis, characterization and catalytic activity in the oxidation of prochiral sulfides and olefins

2016 / Polyhedron

Seven chiral dioxidomolybdenum(VI) complexes with tridentate Schiff bases were synthesized by monocondensation of S(+)-1-amino-2-propanol with salicylaldehyde and its derivatives. One- (1H, 13C)… Continue reading Chiral molybdenum(VI) complexes with tridentate Schiff bases derived from S(+)-1-amino-2-propanol: Synthesis, characterization and catalytic activity in the oxidation of prochiral sulfides and olefins

Leah Pandiscia, PhD

Scaffold-hopping of bioactive flavonoids: Discovery of aryl-pyridopyrimidinones as potent anticancer agents that inhibit catalytic role of topoisomerase Iiα

2016 / European Journal of Medicinal Chemistry

A strategy of scaffold-hopping of bioactive natural products, flavones and isoflavones, leading to target-based discovery of potent anticancer agents has… Continue reading Scaffold-hopping of bioactive flavonoids: Discovery of aryl-pyridopyrimidinones as potent anticancer agents that inhibit catalytic role of topoisomerase Iiα

Leah Pandiscia, PhD

Introduction of perfluoroalkyl chain into the esterifying moiety of bacteriochlorophyll c in the green sulfur photosynthetic bacterium Chlorobaculum tepidum by pigment biosynthesis

2016 / Bioorganic & Medicinal Chemistry

The green sulfur photosynthetic bacterium Chlorobaculum (Cba.) tepidum was grown in liquid cultures containing perfluoro-1-decanol, 1H,1H,2H,2H-heptadecafluoro-1-decanol [CF3(CF2)7(CH2)2OH] or 1H,1H-nonadecafluoro-1-decanol [CF3(CF2)8CH2OH], to introduce rigid and fluorophilic chains… Continue reading Introduction of perfluoroalkyl chain into the esterifying moiety of bacteriochlorophyll c in the green sulfur photosynthetic bacterium Chlorobaculum tepidum by pigment biosynthesis

Leah Pandiscia, PhD

Partial characterization and anticancer activities of purified glycoprotein extracted from green seaweed Codium decorticatum

2016 / Journal of Functional Foods

Glycoprotein (GLP) with a molecular mass of ~48 kDa was isolated from Codium decorticatum. Further, characterization of GLP and its potent anti-cancer activities… Continue reading Partial characterization and anticancer activities of purified glycoprotein extracted from green seaweed Codium decorticatum

Leah Pandiscia, PhD

The “racemic approach” in the evaluation of the enantiomeric NorA efflux pump inhibition activity of 2-phenylquinoline derivatives   

2016 / Journal of Pharmaceutical and Biomedical Analysis

Among the mechanisms adopted by bacteria, efflux pumps (EPs) have been recognized as being significantly involved in contributing to resistance… Continue reading The “racemic approach” in the evaluation of the enantiomeric NorA efflux pump inhibition activity of 2-phenylquinoline derivatives   

Leah Pandiscia, PhD
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