The main aim of this study is to investigate the interaction of 7-fluoro-2,2-dimethyl-2,3-dihydroquinazolin-4(1H)-one with lysozyme through various spectrophotometric studies. The… Continue reading Importance of fluorine in 2, 3-Dihydroquinazolinone and its interaction study with lysozyme
Leah Pandiscia, PhD
July 28, 2017
This study proposes a novel method for the detection of inert gas radon using a label-free, specific, fluorescence-sensing aptamer in… Continue reading A novel detection of radon based on its decay product inducing conformational changes of an aptamer probe
Leah Pandiscia, PhD
July 28, 2017
The presence of Lewy bodies and Lewy neurites is a major pathological hallmark of Parkinson’s disease and is hypothesized to… Continue reading Mechanistic study of the inhibitory activity of Geum urbanum extract against α-Synuclein fibrillation
Leah Pandiscia, PhD
July 28, 2017
The ferrous iron transporter FeoB is an important factor in the iron metabolism of many bacteria. Although several structural studies… Continue reading Studies on the X-Ray and Solution Structure of FeoB from Escherichia coli BL21
Leah Pandiscia, PhD
July 28, 2017
The mechanism whereby phospholipids rapidly flip-flop in the endoplasmic reticulum (ER) membrane remains unknown. We previously demonstrated that the presence… Continue reading Membrane-Spanning Sequences in Endoplasmic Reticulum Proteins Promote Phospholipid Flip-Flop
Leah Pandiscia, PhD
July 28, 2017
An extensible multidimensional colorimetric sensor array for the detection of protein is developed based on DNA functionalized gold nanoparticles (DNA-AuNPs)… Continue reading Multidimensional colorimetric sensor array for discrimination of proteins
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Chrysin, one of natural flavonoid compounds, has recently been found to possess anti-inflammatory, antiallergic and anticancer properties. To increase its… Continue reading Directional modification of chrysin for exerting apoptosis and enhancing significantly anti-cancer effects of 10-hydroxy camptothecin
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Nanoparticles could act as the efficient catalyst or the inhibitor towards the fibrillation pathway of biomolecules. In the present work,… Continue reading Elucidating the role of surfactant dispersed CNTs towards HSA fibrillation in vitro- A multiple spectroscopic approach
Leah Pandiscia, PhD
July 28, 2017
Antimicrobial activities have previously been described by traditional Eastern medicine in Chilopoda body extracts, but until now no bioactive peptides… Continue reading Lacrain: the first antimicrobial peptide from the body extract of the Brazilian centipede Scolopendra viridicornis
Leah Pandiscia, PhD
July 28, 2017
The green sulfur photosynthetic bacterium Chlorobaculum (Cba.) tepidum was grown in liquid cultures containing perfluoro-1-decanol, 1H,1H,2H,2H-heptadecafluoro-1-decanol [CF3(CF2)7(CH2)2OH] or 1H,1H-nonadecafluoro-1-decanol [CF3(CF2)8CH2OH], to introduce rigid and fluorophilic chains… Continue reading Introduction of perfluoroalkyl chain into the esterifying moiety of bacteriochlorophyll c in the green sulfur photosynthetic bacterium Chlorobaculum tepidum by pigment biosynthesis
Leah Pandiscia, PhD
July 28, 2017
The GTPase Arf1 is the major regulator of vesicle traffic at both the cis- and trans-Golgi. Arf1 is activated at the cis-Golgi by… Continue reading Structural Insights into Arl1-Mediated Targeting of the Arf-GEF BIG1 to the trans-Golgi
Leah Pandiscia, PhD
July 28, 2017
Mammalian mitochondrial cytochromes c (cyts c) has a conserved Leu94 which is replaced by valine/isoleucine in some lower eukaryotes and prokaryotes. It is… Continue reading Structural and thermodynamic characterisation of L94F mutant of horse cytochrome c
Leah Pandiscia, PhD
July 28, 2017
In enterohemorrhagic Escherichia coli (EHEC), the QseEF two-component system causes attaching and effacing (AE) lesion on epithelial cells. QseE histidine kinase senses… Continue reading Characterization of the sensor domain of QseE histidine kinase from Escherichia coli
Leah Pandiscia, PhD
July 28, 2017
Glycoprotein (GLP) with a molecular mass of ~48 kDa was isolated from Codium decorticatum. Further, characterization of GLP and its potent anti-cancer activities… Continue reading Partial characterization and anticancer activities of purified glycoprotein extracted from green seaweed Codium decorticatum
Leah Pandiscia, PhD
July 28, 2017
Recently, high-intensity pulsed electric field (PEF) has successfully used in improvement of antioxidant activity. Ser-His-Cys-Met-Asn (SHCMN) obtained from soybean protein… Continue reading Effect of pulsed electric field (PEF) on structures and antioxidant activity of corn source peptides-SHCMN
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017