Found 9617 Results / Page 406 of 481
2016 / Vaccine
Development of acellular pertussis vaccine (aPV) requires purification of several components from Bordetella pertussis. While the components pertussis toxin (PT) and filamentous… Continue reading Purification design and practice for pertactin, the third component of acellular pertussis vaccine, from Bordetella pertussis
2016 / Cell Chemical Biology
Modern enzyme complexes are characterized by a high catalytic efficiency and allosteric communication between the constituting protein subunits. We were… Continue reading Ancestral Tryptophan Synthase Reveals Functional Sophistication of Primordial Enzyme Complexes
2016 / Archives of Oral Biology
Fish epidermal antimicrobial peptides, such as pleurocidin, are cathelicidins with broad-spectrum antimicrobial activity against gram negative and gram-positive bacteria, as… Continue reading Pleurocidin congeners demonstrate activity against Streptococcus and low toxicity on gingival fibroblasts
2016 / Biosensors and Bioelectronics
Although conventional enzyme-linked immunosorbent assays (ELISA) and related assays have been widely applied for the diagnosis of diseases, many of… Continue reading Peptidic β-sheet binding with Congo Red allows both reduction of error variance and signal amplification for immunoassays
2016 / Biophysical Journal
The forkhead family of transcription factors (Fox) controls gene transcription during key processes such as regulation of metabolism, embryogenesis, and… Continue reading Three-Dimensional Domain Swapping Changes the Folding Mechanism of the Forkhead Domain of FoxP1
2016 / Biophysical Journal
Caveolins mediate the formation of caveolae, which are small omega-shaped membrane invaginations involved in a variety of cellular processes. There… Continue reading A pH-Mediated Topological Switch within the N-Terminal Domain of Human Caveolin-3
2016 / Biophysical Journal
Coiled-coil fusions are a useful approach to enforce dimerization in protein engineering. However, the final structures of coiled-coil fusion proteins… Continue reading Competition between Coiled-Coil Structures and the Impact on Myosin-10 Bundle Selection
2016 / International Journal of Biological Macromolecules
The folding and unfolding mechanisms of a small monomeric protein, Dihydrofolate reductase (1.5.1.3.) from a new variant, Zebrafish (zDHFR) has been studied through GdnHCl… Continue reading Investigation of folding unfolding process of a new variant of Dihydrofolate Reductase protein from Zebra fish
2016 / Reference Module in Chemistry, Molecular Sciences and Chemical Engineering
Circular Dichroism (CD) is the differential absorption of left and right circularly polarised light by a chiral substance. The phenomenon… Continue reading Circular Dichroism Spectrometers
2016 / Molecules
Three new indole alkaloids, named naucleamide G (1), and nauclealomide B and C (5 and 6), were isolated from the n-BuOH-soluble fraction of… Continue reading Indole Alkaloids from the Leaves of Nauclea officinalis
2016 / Food Biophysics
Encapsulation technologies using proteins or polysaccharides can be employed with the purpose of solubilizing and protecting carotenoids. However, information on… Continue reading Heat Treatment and β-Carotene Incorporation Effect in the Interaction of β-Lactoglobulin and Carboxymethylcellulose System
2016 / International Journal of Peptide Research and Therapeutics
Two new somatostatin analogs with a characteristic part of the sequence -c(Cys-Phe-Trp-Lys-Thr-Cys)- and with two histidine and two aspartic acid… Continue reading The Coordination Abilities of New Cyclic Analogs of Somatostatin
2016 / Tetrahedron
Phytochemical investigation on Asterothamnus centrali-asiaticus afforded four new sesquiterpenes, asterothamnones A–D (1–4), and three new benzofuran derivatives (5–7) together with ten known… Continue reading New sesquiterpenes and benzofuran derivatives from the aerial parts of Asterothamnus centrali-asiaticus
2016 / International Journal of Biological Macromolecules
Hereditary hemochromatosis factor E (HFE) is a type 1 transmembrane protein, and acts as a negative regulator of iron-uptake. The… Continue reading Structural Basis of Urea-induced Unfolding: Unraveling the Folding Pathway of Hemochromatosis Factor E
2016 / Biochemical and Biophysical Research Communications
Humanin comprising 24 amino acid residues is a bioactive peptide that has been isolated from the brain tissue of patients… Continue reading Solution NMR structure and inhibitory effect against amyloid-β fibrillation of Humanin containing a D-isomerized serine residue
2016 / Colloids and Surfaces B: Biointerfaces
Nanodiscs are discoidal particles with a planar phospholipid bilayer enwrapped by proteins such as apolipoprotein A-I. Nanodiscs have been widely… Continue reading Formation of Size-Controlled, Denaturation-Resistant Lipid Nanodiscs by an Amphiphilic Self-Polymerizing Peptide
2016 / Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
Maltodextrin glucosidase (MalZ) hydrolyses short malto-oligosaccharides from the reducing end releasing glucose and maltose in Escherichia coli. MalZ is a highly aggregation… Continue reading Role of N-terminal region of Escherichia coli Maltodextrin Glucosidase in folding and function of the protein
2016 / Biochemical Pharmacology
A series of compounds containing the sulfonamide scaffold were synthesized and screened for their in vitro anticancer activity against a representative panel… Continue reading N-(2-methyl-indol-1H-5-yl)-1-naphthalenesulfonamide: a novel reversible antimitotic agent inhibiting cancer cell motility
2016 / Journal of Inorganic Biochemistry
Three ruthenium complexes [RuCl(CTZ)(bipy)(P-P)]PF6 [P-P = 1,2-bis(diphenylphosphino)ethane (dppe-1), 1,4-bis(diphenylphosphino)butane (dppb-2) and 1,1′-bis(diphenylphosphino)ferrocene (dppf-3), bipy = 2,2′-bipiridine and clotrimazole (CTZ) 1-[(2-chlorophenyl)diphenylmethyl]-1H-imidazole] were synthesized. These complexes were… Continue reading Ru(II)/clotrimazole/diphenylphosphine/bipyridine complexes: Interaction with DNA, BSA and biological potencial against tumor cell lines and Mycobacterium tuberculosis
2016 / Fitoterapia
Adeninealkylresorcinol (1), an unusual alkylresorcinol with adenine-alkylresorcinol conjoined skeleton, was isolated from an endophytic fungus Lasiodiplodia sp. obtained from a traditional Chinese… Continue reading Adeninealkylresorcinol, the First Alkylresorcinol Tethered with Nucleobase from Lasiodiplodia sp.
