Found 9617 Results / Page 448 of 481

Two variants of the major serine protease inhibitor from the sea anemone Stichodactyla helianthus, expressed in Pichia pastoris

2016 / Protein Expression and Purification

The major protease inhibitor from the sea anemone Stichodactyla helianthus (ShPI-1) is a non-specific inhibitor that binds trypsin and other trypsin-like enzymes,… Continue reading Two variants of the major serine protease inhibitor from the sea anemone Stichodactyla helianthus, expressed in Pichia pastoris

Leah Pandiscia, PhD

Functional characterization of a thermostable methionine adenosyltransferase from Thermus thermophilus HB27

2016 / Frontiers of Chemical Science and Engineering

MATTt (a thermostable methionine adenosyltransferase from Thermus thermophilusHB27) was overexpressed in Escherchia coli and purified using Ni-NTA affinity column. The enzymatic activity of… Continue reading Functional characterization of a thermostable methionine adenosyltransferase from Thermus thermophilus HB27

Leah Pandiscia, PhD

Oligomerization as a strategy for cold adaptation: Structure and dynamics of the GH1 β-glucosidase from Exiguobacterium antarcticum B7

2016 / Scientific Reports

Psychrophilic enzymes evolved from a plethora of structural scaffolds via multiple molecular pathways. Elucidating their adaptive strategies is instrumental to… Continue reading Oligomerization as a strategy for cold adaptation: Structure and dynamics of the GH1 β-glucosidase from Exiguobacterium antarcticum B7

Leah Pandiscia, PhD

Collagencin, an antibacterial peptide from fish collagen: Activity, structure and interaction dynamics with membrane

2016 / Biochemical and Biophysical Research Communications

In this study, we first report characterization of collagencin, an antimicrobial peptide identified from fish collagen hydrolysate. The peptide completely… Continue reading Collagencin, an antibacterial peptide from fish collagen: Activity, structure and interaction dynamics with membrane

Leah Pandiscia, PhD

Proline cis-trans isomerization and its implications for the dimerization of analogues of cyclopeptide stylostatin 1: a combined computational and experimental study

2016 / Physical Chemistry Chemical Physics

Cis and trans proline conformers are often associated with dramatic changes in the biological function of peptides. A slow equilibrium between cis and trans Ile–Pro amide bond… Continue reading Proline cis-trans isomerization and its implications for the dimerization of analogues of cyclopeptide stylostatin 1: a combined computational and experimental study

Leah Pandiscia, PhD

Insights into the C-terminal Peptide Binding Specificity of the PDZ domain of neuronal Nitric Oxide Synthase. Characterization of the Interaction with the tight-junction protein Claudin-3

2016 / The Journal of Biological Chemistry

Neuronal nitric-oxide synthase, unlike its endothelial and inducible counterparts, displays a PDZ (PSD-95/Dlg/ZO-1) domain located at its N terminus involved… Continue reading Insights into the C-terminal Peptide Binding Specificity of the PDZ domain of neuronal Nitric Oxide Synthase. Characterization of the Interaction with the tight-junction protein Claudin-3

Leah Pandiscia, PhD

pH Induced Conformational Transitions in the Transforming Growth Factor β-Induced Protein (TGFβIp) Associated Corneal Dystrophy Mutants

2016 / Scientific Reports

Most stromal corneal dystrophies are associated with aggregation and deposition of the mutated transforming growth factor-β induced protein (TGFβIp). The… Continue reading pH Induced Conformational Transitions in the Transforming Growth Factor β-Induced Protein (TGFβIp) Associated Corneal Dystrophy Mutants

Leah Pandiscia, PhD

Syntheses, Structures and Catalytic Properties of Chiral Co(II) Coordination Polymers based on (R)-4-(4-(1-Carboxyethoxy)phenoxy)benzoic Acid

2016 / Polyhedron

To investigate the construction of novel chiral coordination polymers and the effect of different substituents on the ligands, three complexes,… Continue reading Syntheses, Structures and Catalytic Properties of Chiral Co(II) Coordination Polymers based on (R)-4-(4-(1-Carboxyethoxy)phenoxy)benzoic Acid

Leah Pandiscia, PhD

Physical Insight into Ultrasound-Assisted Biodesulfurization using Free and Immobilized Cells of Rhodococcus rhodochrous MTCC 3552

2016 / Chemical Engineering Journal

Biodesulfurization has emerged as potential alternative to oxidative desulfurization and hydrodesulfurization. However, main impediment in commercial application of biodesulfurization process… Continue reading Physical Insight into Ultrasound-Assisted Biodesulfurization using Free and Immobilized Cells of Rhodococcus rhodochrous MTCC 3552

Leah Pandiscia, PhD
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