Found 9617 Results / Page 459 of 481
2016 / Journal of Chemical and Engineering Data
Interaction of myoglobin with cationic surfactants hexadecyltrimethylammonium bromide (HTAB), gemini surfactant 16-2-16 (dimethylene-1,2-bis(hexadecyldimethylammonium bromide)) and nonionic surfactant Mega 10 (N-decanoyl-N-methylglucamine)… Continue reading Interaction of Myoglobin with Cationic and Nonionic Surfactant in Phosphate Buffer Media
2016 / Chemical Biology and Drug Design
HirudinP6 is a glycosylated and sulfated high affinity thrombin inhibitory protein isolated from Hirudineria manillensis. In this study, designing of novel… Continue reading Structural and Functional Characterization of Hirudin P6 Derived Novel Bivalent Thrombin Inhibitors – Studying the Effect of Linker Length and Glycosylation on Their Function
2016 / Scientific Reports
TAR DNA-binding protein 43 (TDP-43) is a DNA/RNA-binding protein containing two consecutive RNA recognition motifs (RRM1 and RRM2) in tandem.… Continue reading A molecular mechanism realizing sequence-specific recognition of nucleic acids by TDP-43
2016 / Toxins
Animal venom (e.g., scorpion) is a rich source of various protein and peptide toxins with diverse physio-/pharmaco-logical activities, which generally… Continue reading Structure-Activity Relationship of Chlorotoxin-Like Peptides
2016 / International Journal of Biological Macromolecules
Glyco-oxidation of proteins has implications in the progression of diabetes type 2. Human serum albumin is prone to glyco-oxidative attack… Continue reading Neo-epitopes on methylglyoxal modified human serum albumin lead to aggressive autoimmune response in diabetes
2016 / Inorganica Chimica Acta
The metal-mediated base pair P–Ag(I)–P involving the bidentate ligand 1H-imidazo[4,5-f][1,10]phenanthroline (P) was investigated within a B-DNA duplex. The underlying tetrahedral… Continue reading Enantiospecific formation of a metal-mediated base pair inside a DNA duplex
2016 / Antimicrobial Agents and Chemotherapy
Synthetic peptides encompassing sequences related to the complementarity-determining regions of antibodies or derived from their constant region (Fc peptides) were… Continue reading Dissecting the structure-function relationship of a fungicidal peptide derived from the constant region of human immunoglobulins
2016 / Antimicrobial Agents and Chemotherapy
Two laboratory mutants of NDM-1 were generated by replacing the isoleucine at position 35 with threonine and serine residues: the… Continue reading Kinetic study of laboratory mutants of NDM-1 metallo-β-lactamase: the importance of an isoleucine at position 35
2016 / Plant Science
Dehydrin, which is one of the late embryogenesis abundant (LEA) proteins, is involved in the ability of plants to tolerate… Continue reading The Arabidopsis KS-type dehydrin recovers lactate dehydrogenase activity inhibited by copper with the contribution of His residues
2016 / Chemical Communications
Cisplatin (CDDP) can be encapsulated within the central cavity of reconstituted (apo)ferritin, (A)Ft, to form a drug-loaded protein of potential… Continue reading Cisplatin encapsulation within a ferritin nanocage: a high-resolution crystallographic study
2016 / Archives of Biochemistry and Biophysics
Understanding the interaction between graphene oxide (GO) and the biomolecules is fundamentally essential, especially for disease- and drug-related peptides and… Continue reading Interaction of graphene oxide with albumins: Effect of size, pH, and temperature
2016 / Toxicology Reports
Cigarette smoke (CS) is an important source of morbidity and early mortality worldwide. Besides causing various life-threatening diseases, CS is… Continue reading Interaction of p-benzoquinone with hemoglobin in smoker’s blood causes alteration of structure and loss of oxygen binding capacity
2016 / International Journal of Biological Macromolecules
Three new diphenylsubstituted spirotriazolidine- and thiazolidinone–acridines were prepared and their interaction with calf thymus DNA investigated with UV–vis, fluorescence, circular… Continue reading New spiro tria(thia)zolidine-acridines as topoisomerase inhibitors, DNA binders and cytostatic compounds
2016 / Journal of Controlled Release
Poly(ethylene glycol) (PEG) may be covalently conjugated to peptide drugs to overcome their rapid clearance but in doing so their… Continue reading A novel combined strategy for the physical PEGylation of polypeptides
2016 / European Polymer Journal
Here, for the first time, branched polyaminoacids bearing α-amino acids as side functions, namely PAA-co-AA and PGA-co-AA, are prepared by… Continue reading A facile way to build up branched high functional polyaminoacids with tunable physicochemical and biological properties
2016 / Scientific Reports
Enzymes catalyze reactions with exceptional selectivity and rate acceleration but are often limited by instability. Towards a generic route to… Continue reading SpyRing interrogation: analyzing how enzyme resilience can be achieved with phytase and distinct cyclization chemistries
2016 / Nature Communications
Nature has developed striking light-powered proteins such as bacteriorhodopsin, which can convert light energy into conformational changes for biological functions.… Continue reading A light-driven three-dimensional plasmonic nanosystem that translates molecular motion into reversible chiroptical function
2016 / Macromolecular Rapid Communications
Optically active nano- and microparticles have constituted a significant category of advanced functional materials. However, constructing optically active particles derived… Continue reading Emulsification-Induced Homohelicity in Racemic Helical Polymer for Preparing Optically Active Helical Polymer Nanoparticles
2016 / Scientific Reports
Advanced glycation end-products (AGEs) resulting from non-enzymatic glycation are one of the major factors implicated in secondary complications of diabetes.… Continue reading Green synthesis of silver nanoparticles and characterization of their inhibitory effects on AGEs formation using biophysical techniques
2016 / Journal of Photochemistry and Photobiology A: Chemistry
Herein, we designed photoluminescent polymer aggregates surrounded by organic media containing (S)-/(R)-limonene and (1S)-/(1R)-α-pinene as an artificial model of an… Continue reading Tempo-spatial chirogenesis. Limonene-induced mirror symmetry breaking of Sisingle bondSi bond polymers during aggregation in chiral fluidic media
