Found 9617 Results / Page 54 of 481
2021 / Communication Chemistry
Anions often quench fluorescence (FL). However, strong ionic hydrogen bonding between fluorescent dyes and anion molecules has the potential to… Continue reading Environment-sensitive emission of anionic hydrogen-bonded urea-derivative–acetate-ion complexes and their aggregation-induced emission enhancement
2021 / Scientific Reports
The thermodynamic properties of few-layer graphene arbitrarily stacked on LiNbO3 crystal were characterized by measuring the parameters of a surface… Continue reading Possible pair-graphene structures govern the thermodynamic properties of arbitrarily stacked few-layer graphene
2021 / Scientific Reports
Specific guanine rich nucleic acid sequences can form non-canonical structures, like the four stranded G-quadruplex (GQ). We studied the GQ-forming… Continue reading Characterization of a G-quadruplex from hepatitis B virus and its stabilization by binding TMPyP4, BRACO19 and PhenDC3
2021 / Scientific Reports
A nucleotide repeat expansion (NRE), (G4C2)n, located in a classically noncoding region of C9orf72 (C9), is the most common genetic… Continue reading The effects of molecular crowding and CpG hypermethylation on DNA G-quadruplexes formed by the C9orf72 nucleotide repeat expansion
2021 / Scientific Reports
G-quadruplex (G4) structures are considered a promising therapeutic target in cancer. Since Ayurveda, Piperine has been known for its medicinal… Continue reading Piperine analogs arrest c-myc gene leading to downregulation of transcription for targeting cancer
2021 / Scientific Reports
Sweet taste perception is mediated by a heterodimeric receptor formed by the assembly of the TAS1R2 and TAS1R3 subunits. TAS1R2… Continue reading Biophysical and functional characterization of the human TAS1R2 sweet taste receptor overexpressed in a HEK293S inducible cell line
2021 / Nature Communications
Infectious diseases are worldwide a major cause of morbidity and mortality. Fast and specific detection of pathogens such as bacteria… Continue reading Remote near infrared identification of pathogens with multiplexed nanosensors
2021 / biomolecules
The capsid of human immunodeficiency virus type 1 (HIV-1) is a shell that encloses viral RNA and is highly conserved… Continue reading Small-Molecule Anti-HIV-1 Agents Based on HIV-1 Capsid Proteins
2021 / ACS Omega 2021
The hydration behavior of LiOH, LiOH·H2O, and LiCl was observed by near-infrared (NIR) spectroscopy. Anhydrous LiOH showed two absorption bands… Continue reading Hydration of LiOH and LiCl─Near-Infrared Spectroscopic Analysis
2021 / Nature Communications
In antibody light chain (AL) amyloidosis, overproduced light chain (LC) fragments accumulate as fibrils in organs and tissues of patients.… Continue reading Dissection of the amyloid formation pathway in AL amyloidosis
2021 / Nature Communications
Inactivation of the phytohormone auxin plays important roles in plant development, and several enzymes have been implicated in auxin inactivation.… Continue reading The main oxidative inactivation pathway of the plant hormone auxin
2021 / Nature Communications
During injured tissue regeneration, the extracellular matrix plays a key role in controlling and coordinating various cellular events by binding… Continue reading Efficient protein incorporation and release by a jigsaw-shaped self-assembling peptide hydrogel for injured brain regeneration
2021 / Nature Communications
Posttranslational mechanisms play a key role in modifying the abundance and function of cellular proteins. Among these, modification by advanced… Continue reading Mapping protein carboxymethylation sites provides insights into their role in proteostasis and cell proliferation
2021 / Nature Communications
The acidic tumor microenvironment in melanoma drives immune evasion by up-regulating cyclic adenosine monophosphate (cAMP) in tumor-infiltrating monocytes. Here we… Continue reading Therapeutic melanoma inhibition by local micelle-mediated cyclic nucleotide repression
2021 / Nature Communications
The post-translational modification of proteins with ubiquitin (Ub) and Ub-like modifiers (Ubls) represents one of the most important regulators in… Continue reading A modular toolbox to generate complex polymeric ubiquitin architectures using orthogonal sortase enzymes
2021 / Nature Communications
Rhizobium etli, a nitrogen-fixing bacterial symbiont of legume plants, encodes an essential l-asparaginase (ReAV) with no sequence homology to known… Continue reading Crystal structures of the elusive Rhizobium etli l-asparaginase reveal a peculiar active site
2021 / Nature Communications
Antibodies bind antigens via flexible loops called complementarity-determining regions (CDRs). These are usually 6-20 residues long. However, some bovine antibodies… Continue reading Mechanistic principles of an ultra-long bovine CDR reveal strategies for antibody design
2021 / Nature Structural & Molecular Biology
Carboxysomes in cyanobacteria enclose the enzymes Rubisco and carbonic anhydrase to optimize photosynthetic carbon fixation. Understanding carboxysome assembly has implications… Continue reading Scaffolding protein CcmM directs multiprotein phase separation in β-carboxysome biogenesis
2021 / NPG Asia Materials
The diffusion of light by random materials is a general phenomenon that appears in many different systems, spanning from colloidal… Continue reading Disordered photonics behavior from terahertz to ultraviolet of a three-dimensional graphene network
2021 / Scientific Reports
Sweet taste perception is mediated by a heterodimeric receptor formed by the assembly of the TAS1R2 and TAS1R3 subunits. TAS1R2… Continue reading Biophysical and functional characterization of the human TAS1R2 sweet taste receptor overexpressed in a HEK293S inducible cell line
