Found 9617 Results / Page 55 of 481
2021 / Scientific Reports
α-Conotoxins are small disulfide-rich peptides targeting nicotinic acetylcholine receptors (nAChRs) characterised by a CICII-Xm-CIII-Xn-CIV framework that invariably adopt the native… Continue reading Rigidity of loop 1 contributes to equipotency of globular and ribbon isomers of α-conotoxin AusIA
2021 / Cell Death & Diffirentiation
Anti-apoptotic Bcl-2-family members not only act at mitochondria but also at the endoplasmic reticulum, where they impact Ca2+ dynamics by… Continue reading Bcl-xL acts as an inhibitor of IP3R channels, thereby antagonizing Ca2+-driven apoptosis
2021 / Scientific Reports
Quenchbody (Q-body) is a quench-based fluorescent immunosensor labeled with fluorescent dye(s) near the antigen-binding site of an antibody. Q-bodies can… Continue reading Evaluation and selection of potent fluorescent immunosensors by combining fluorescent peptide and nanobodies displayed on yeast surface
2021 / Communications Biology
Plasmodium falciparum-infected erythrocytes (IE) sequester in the placenta via surface protein VAR2CSA, which binds chondroitin sulfate A (CSA) expressed on… Continue reading Allelic variants of full-length VAR2CSA, the placental malaria vaccine candidate, differ in antigenicity and receptor binding affinity
2021 / npj Science of Food
In this study, the interfacial ability of α-terpineol (α-TOH) was reported, followed by its trapping into oil-in-water (O/W) nanoemulsion as… Continue reading Comprehensive study of α-terpineol-loaded oil-in-water (O/W) nanoemulsion: interfacial property, formulation, physical and chemical stability
2021 / Scientific Reports
Porous materials are relevant for a broad range of technologies from catalysis and filtration, to tissue engineering and lightweight structures.… Continue reading Hierarchical porous materials made by stereolithographic printing of photo-curable emulsions
2021 / Scientific Reports
In recent times, fused azaheterocycles emerged as impressive therapeutic agents. Binding studies of such azaheterocycles with biomolecules is an important… Continue reading Visible-light driven regioselective synthesis, characterization and binding studies of 2-aroyl-3-methyl-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidines with DNA and BSA using biophysical and computational techniques
2021 / Scientific Reports
Self-regulated “smart” insulin administration system that mimic pancreatic endocrine function would be highly desirable for diabetes management. Here, a glucose-responsive… Continue reading Insulin smart drug delivery nanoparticles of aminophenylboronic acid–POSS molecule at neutral pH
2021 / Electronic Journal of Biothechnology
Opsonization, is the molecular mechanism by which target molecules promote interactions with phagocyte cell surface receptors to remove unwanted cells… Continue reading An in vitro model mimicking the complement system to favor directed phagocytosis of unwanted cells
2021 / Chirality
The application of the exciton chirality method (ECM) to interpret electronic circular dichroism (ECD) spectra is a well-established and still… Continue reading ECD exciton chirality method today: a modern tool for determining absolute configurations
2021 / Nature Communications
The microtubule-associated protein tau is implicated in the formation of oligomers and fibrillar aggregates that evade proteostasis control and spread… Continue reading Dynamic interactions and Ca2+-binding modulate the holdase-type chaperone activity of S100B preventing tau aggregation and seeding
2021 / Nature Communications
Lysocin E is a lipopeptide with antibiotic activity against methicillin-resistant Staphylococcus aureus. For unclear reasons, the antibacterial activity of lysocin… Continue reading Serum apolipoprotein A-I potentiates the therapeutic efficacy of lysocin E against Staphylococcus aureus
2021 / Scientific reports
The cellular prion protein (PrPC) is a mainly α-helical 208-residue protein located in the pre- and postsynaptic membranes. For unknown… Continue reading Zn(II) binding causes interdomain changes in the structure and flexibility of the human prion protein
2021 / Cell Death & Differenitation
Anti-apoptotic Bcl-2-family members not only act at mitochondria but also at the endoplasmic reticulum, where they impact Ca2+ dynamics by… Continue reading Bcl-xL acts as an inhibitor of IP3R channels, thereby antagonizing Ca2+-driven apoptosis
2021 / Scientific reports
The site selectivity for lysine conjugation on a native protein is difficult to control and characterize. Here, we applied mass… Continue reading Selective and predicable amine conjugation sites by kinetic characterization under excess reagents
2021 / Scientific reports
The structures of a cyanophage small heat shock protein (sHSP) were determined as octahedrons of 24-mers and 48-mers and as… Continue reading Multiple nanocages of a cyanophage small heat shock protein with icosahedral and octahedral symmetries
2021 / Scientific reports
Self-regulated “smart” insulin administration system that mimic pancreatic endocrine function would be highly desirable for diabetes management. Here, a glucose-responsive… Continue reading Insulin smart drug delivery nanoparticles of aminophenylboronic acid–POSS molecule at neutral pH
2021 / Nature Communications
Expanding the useful lifespan of materials is becoming highly desirable, and self-healing and self-repairing materials may become valuable commodities. The… Continue reading Redox-responsive self-healing materials formed from host–guest polymers
2021 / Scientific reports
Anhydrobiosis, one of the most extensively studied forms of cryptobiosis, is induced in certain organisms as a response to desiccation.… Continue reading Desiccation-induced fibrous condensation of CAHS protein from an anhydrobiotic tardigrade
2021 / Scientific reports
A patterned transparent electrode is a crucial component of state-of-the-art wearable devices and optoelectronic devices. However, most of the patterning… Continue reading Highly efficient patterning technique for silver nanowire electrodes by electrospray deposition and its application to self-powered triboelectric tactile sensor
