Studies of salt effects on enzyme activity have typically been conducted at standard temperatures and pressures, thus missing effects which… Continue reading Perchlorate salts confer psychrophilic characteristics in α-chymotrypsin
Carlos Morillo
September 7, 2021
A novel, dual gradient LC method for quantification of vardenafil (VR) and its degradant products was developed with a multivariate… Continue reading A Comprehensive Stability Study of Vardenafil Using Quality by Design Approach
Carlos Morillo
September 7, 2021
Planar chiral boron–nitrogen heteroarenes based on [2.2]paracyclophane were successfully synthesized in a few steps as a new family of circularly… Continue reading Planar Chiral B–N Heteroarenes Based on [2.2]Paracyclophane as Circularly Polarized Luminescence Emitters
Heather Haffner
August 23, 2021
A simple and general method is presented herein for the in situ preparations of circularly polarized luminescence (CPL)-active microcrystals with… Continue reading Full-Color and White Circularly Polarized Luminescence of Hydrogen-Bonded Ionic Organic Microcrystals
Heather Haffner
August 23, 2021
Double-twisted cyclic binaphthyls, in which two naphthalenes are tethered by -O(CH2)nO- linkage (n=1–3), have been synthesized. X-ray analyses and DFT… Continue reading Small Figure-Eight Luminophores: Double-Twisted Tethered Cyclic Binaphthyls Boost Circularly Polarized Luminescence
Heather Haffner
August 20, 2021
Heather Haffner
August 20, 2021
Nanographenes are emerging as a distinctive class of functional materials for electronic and optical devices. It is of remarkable significance… Continue reading Oxidative cyclo-rearrangement of helicenes into chiral nanographenes
Carlos Morillo
August 19, 2021
Carlos Morillo
August 16, 2021
Various methods have been developed for metal ion detection, and most of them suffer from limitations including requirement of multiple-step… Continue reading Functionalization of gold nanoparticles using guanidine thiocyanate for sensitive and selective visual detection of Cd2+
Carlos Morillo
August 16, 2021
Four new alkaloids, nonialkaloids A–D (1–4) and six known analogues (5–10) were isolated from the noni juice. Among the new… Continue reading New alkaloids from the noni juice with potential α-glucosidase inhibitory activity
Carlos Morillo
August 16, 2021
Phytochemical study on a non-medicinal part of a plant material for herbal medicine, the roots of Schisandra chinensis, was conducted… Continue reading Studies on non-medicinal parts of plant materials: Triterpenes from the roots of Schisandra chinensis
Carlos Morillo
August 16, 2021
Herein, we describe the synthesis of highly emissive amphiphilic N-annulated PBI 1 decorated with oligo ethylene glycol (OEG) side chains.… Continue reading Globular Aggregates Stemming from the Self-Assembly of an Amphiphilic N-Annulated Perylene Bisimide in Aqueous Media
Carlos Morillo
August 16, 2021
Neuroinflammation is emerging as a crucial reason of major neurodegenerative diseases in recent years. Increasingly evidences have supported that bioactive… Continue reading Neuroprotective and anti-inflammatory phenylethanoid glycosides from the fruits of Forsythia suspensa
Carlos Morillo
August 16, 2021
Ginkgo biloba (Ginkgoaceae), commonly known as “ginkgo”, is called a living fossil, and it has been cultivated early in human… Continue reading Ginkwanghols A and B, osteogenic coumaric acid-aliphatic alcohol hybrids from the leaves of Ginkgo biloba
Carlos Morillo
September 27, 2021
Chiral glutamide-derived lipids form self-assembled fibrous molecular gels that can be used as HPLC organic phases. In this study, HPLC… Continue reading A Molecular Shape Recognitive HPLC Stationary Phase Based on a Highly Ordered Amphiphilic Glutamide Molecular Gel
Carlos Morillo
August 16, 2021
G-quadruplex (G4) is the most well-known noncanonical conformation of DNA involved in diverse pharmacological and biological contexts. G4 ligands have… Continue reading Tropylium Derivatives as New Entrants that Sense Quadruplex Structures
Carlos Morillo
August 16, 2021
Nα-2-thiophenoyl-d-phenylalanine-2-morpholinoanilide (MMV688845, IUPAC: N-(1-((2-morpholinophenyl)amino)-1-oxo-3-phenylpropan-2-yl)thiophene-2-carboxamide) from the Pathogen Box® library (Medicines for Malaria Ventures, MMV) is a promising lead compound for… Continue reading Racemization-free synthesis of Nα-2-thiophenoyl-phenylalanine-2-morpholinoanilide enantiomers and their antimycobacterial activity
Carlos Morillo
September 27, 2021
Carlos Morillo
August 16, 2021
A methanolic extract of Thai Piper ribesoides showed preferential cytotoxicity against PANC-1 human pancreatic cancer cells under a nutrient-deprived condition,… Continue reading Chemical constituents of Thai Piper ribesoides and their antiausterity activities against the PANC-1 human pancreatic cancer cell line
Carlos Morillo
August 16, 2021
Thirty new pentacyclic triterpenoids, including five oleanane-type (1–5), twenty-three ursane-type (9–23, 26–33) and two taraxerane-type (24 and 25), along with… Continue reading Oxygenated pentacyclic triterpenoids from the stems and branches of Enkianthus chinensis
Carlos Morillo
August 16, 2021