Found 9617 Results / Page 99 of 481
2020 / Journal of Natural Products
The absolute configuration and corrected NMR assignment of 17-hydroxycyclooctatin isolated from Streptomyces sp. M56 recovered from a nest of South African Macrotermes natalensis termites… Continue reading Absolute Configuration and Corrected NMR Assignment of 17-Hydroxycyclooctatin, a Fused 5–8–5 Tricyclic Diterpene
2020 / Bioorganic Chemistry
Phytochemical investigation into the calyx of Physalis alkekengi L. var franchetii (Mast) Makino resulted in the isolation of ten cytotoxic withanolides, including five new… Continue reading Isolation and characterization of cytotoxic withanolides from the calyx of Physalis alkekengi L. var franchetii
2020 / Chemical Engineering Journal
The use of protein nanostructures can be widely applied in medical devices and biomaterials. However, the synthesis of photothermic bovine… Continue reading Near-infrared-driven Au-decorated polymer-metal protein microfibers with bacterial filtration ability for use in photothermal sterilization
2020 / RSC Advances
Eight different culture media were used to culture shellfish Panopea abbreviate associated fungus Aspergillus sp. XBB-4. In a glucose-peptone-yeast (GPY) culture medium supplied with… Continue reading Cytotoxic alkaloids from the marine shellfish-associated fungus Aspergillus sp. XBB-4 induced by an amino acid-directed strategy
2020 / Bioorganic Chemistry
We present here-in the molecular design and chemical synthesis of a novel series of diindoloazepinone derivatives as DNA minor groove… Continue reading Novel diindoloazepinone derivatives as DNA minor groove binding agents with selective topoisomerase I inhibition: Design, synthesis, biological evaluation and docking studies
2020 / Journal of Agriculture and Food Chemistry
IAVPTGVA (Soy1) and LPYP are two soybean peptides, which display a multifunctional behavior, showing in vitro hypocholesterolemic and hypoglycemic activities.… Continue reading “Bottom-Up” Strategy for the Identification of Novel Soybean Peptides with Angiotensin-Converting Enzyme Inhibitory Activity
2020 / Journal of Medicinal Chemistry
αO-conotoxin GeXIVA from Conus generalis is a potent antagonist of the α9α10 nAChR and analgesic in animal models of pain. This peptide… Continue reading Structure and Activity Studies of Disulfide-Deficient Analogues of αO-Conotoxin GeXIVA
2020 / Biochemical and Biophysical Research Communications
N6-methyladenine (m6dA) has been recently discovered in eukaryotic genomic DNA. However, there have been few reports on its biological roles.… Continue reading Destabilisation of the c-kit1 G-quadruplex structure by N6-methyladenosine modification
2020 / Journal of Biosciences
Silkworm silk protein fibroin is widely exploited to develop novel silk-based biomaterials due to its stable β-sheet structure, providing high… Continue reading Glyoxal modification mediates conformational alterations in silk fibroin: Induction of fibrillation with amyloidal features
2020 / International Journal of Biological Macromolecules
MurE ligase is known to play a significant role in peptidoglycan biosynthesis. It catalyzes the addition of meso-diaminopimelic acid to nucleotide… Continue reading Structural and conformational behavior of MurE ligase from Salmonella enterica serovar Typhi at different temperature and pH conditions
2020 / Journal of Biotechnology
Chaperones are a diverse class of molecules known for increasing thermo-stability of proteins, preventing protein aggregation, favoring disaggregation, increasing solubility… Continue reading Application of a protein domain as chaperone for enhancing biological activity and stability of other proteins
2020 / Journal of Controlled Release
Cytosolic protein delivery is important for the development of protein therapeutics towards intracellular targets. Guanidyl polymers exhibit high binding affinity… Continue reading Tailoring guanidyl-rich polymers for efficient cytosolic protein delivery
2020 / Phytochemistry Letters
Investigations of the root extract of Dracaena usambarensis Engl. for anticancer principles led to the characterization of one new homoisoflavonoid, (3S)-3,4ʹ,5,6-tetrahydroxy-7-methoxyhomoisoflavanone (1)… Continue reading Two new flavonoids from Dracaena usambarensis Engl.
2020 / ACS Biomaterials Science & Engineering
In this study, we report a diblock copolymer based on a polyphosphate backbone and pendant phenylboronic acid with glucose sensitivity.… Continue reading Glucose-Sensitive Polyphosphoester Diblock Copolymer for an Insulin Delivery System
2020 / Scientific Reports
Equilibrium dynamics of different folding intermediates and denatured states is strongly connected to the exploration of the conformational space on… Continue reading Transition between protein-like and polymer-like dynamic behavior: Internal friction in unfolded apomyoglobin depends on denaturing conditions
2020 / Materials Science and Engineering: C
Novel antimicrobial agents with a low propensity to develop resistance by microorganisms have contemporary relevance. In this perspective, the present… Continue reading Synthesis and characterization of cecropin peptide-based silver nanocomposites: Its antibacterial activity and mode of action
2020 / RSC Advances
Chiral oligopeptide-naphthalene/Eu(III) hybridized luminophores emit strong circularly polarised solution-state luminescence (CPL) from Eu(III) at 592 and 614 nm (|gCPL| ≤… Continue reading Circularly polarised luminescence (CPL) control of oligopeptide–Eu(iii) hybridized luminophores by interaction with peptide side chains
2010 / New Journal of Chemistry
Solvent chirality transfer using (S)- and (R)-limonenes, which are candidates for renewable volatile bioresources (bp 176 °C/760 Torr or bp 94… Continue reading Limonene magic: noncovalent molecular chirality transfer leading to ambidextrous circularly polarised luminescent π-conjugated polymers
2010 / Polymer Chemistry
Solvent chirality transfer using enantiomeric pairs of limonene and α-pinene allowed for the successful production of optically active poly(9,9-di-n-decylfluorene) (PF10) aggregates with circular dichroism (CD)… Continue reading Ambidextrous circular dichroism and circularly polarised luminescence from poly(9,9-di-n-decylfluorene) by terpene chirality transfer
2016 / Polymer Chemistry
An enantiopair of rigid rod-like helical polysilanes (PSi-S and PSi-R) as a photoscissible scaffold enabled the production of circularly polarised luminescence (CPL)-… Continue reading Aggregation-induced scaffolding: photoscissable helical polysilane generates circularly polarized luminescent polyfluorene
