2022 / Scientific Reports
Plants have served for centuries as sources of compounds useful for human health such as antioxidant, anti-diabetic and antitumor agents.… Continue reading Hippophae rhamnoides L. leaf and twig extracts as rich sources of nutrients and bioactive compounds with antioxidant activity
2022 / Scientific Reports
Recently, an international randomized controlled clinical trial showed that patients with SARS-CoV-2 infection treated orally with the 3-chymotrypsin-like protease (3CLpro)… Continue reading Pro108Ser mutation of SARS-CoV-2 3CLpro reduces the enzyme activity and ameliorates the clinical severity of COVID-19
2022 / Scientific Reports
The transcription factor c-Myb promotes the proliferation of hematopoietic cells by interacting with the KIX domain of CREB-binding protein; however,… Continue reading Rational design of a helical peptide inhibitor targeting c-Myb–KIX interaction
2022 / ChemistryOpen
The relationship between the coordination geometry and photophysical properties of trans-bis[(β-iminomethyl)naphthoxy]platinum(II) was investigated both experimentally and theoretically. A series of… Continue reading Enhancement of Chiroptical Responses of trans-Bis[(β-iminomethyl)naphthoxy]platinum(II) Complexes with Distorted Square Planar Coordination Geometry
2022 / Food Science & Nutrition
Soybean protein isolate (SPI) is a high-quality plant protein that is primarily used to process various soybean products coagulated by… Continue reading Analysis of the gel properties, microstructural characteristics, and intermolecular forces of soybean protein isolate gel induced by transglutaminase
2021 / Chemistry A European Journal
Given the emergence of the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), which particularly threatens older people with comorbidities such as diabetes… Continue reading Modulation of the Conformational Space of SARS-CoV-2 RNA Quadruplex RG-1 by Cellular Components and the Amyloidogenic Peptides α-Synuclein and hIAPP
2022 / Journal of Biomedical Material Research
Single-walled carbon nanotubes (SWNTs) are cylindrical graphitic helix molecules that exhibit superb mechanical and physical properties. Many polymers, such as… Continue reading Application of a cationic amylose derivative loaded with single-walled carbon nanotubes for gene delivery therapy and photothermal therapy of colorectal cancer
2021 / ADVANCED PHOTONICS RESEARCH
Chiral near fields possessing enhanced asymmetry (superchirality), created by the interaction of light with (chiral) nanostructures, potentially provide a route… Continue reading Detecting Antibody–Antigen Interactions with Chiral Plasmons: Factors Influencing Chiral Plasmonic Sensing
2021 / Communications Materials
Antibodies represent highly specific and high binding affinity biomolecular recognition elements for diagnostic assays, biosensors, and therapeutics, but are sensitive… Continue reading Creation of stable water-free antibody based protein liquids
2021 / Chemistry A European Journal
Quadruplex-duplex (Q-D) junctions are increasingly considered promising targets for medicinal and technological applications. Here, a Q-D hybrid with a hairpin-type… Continue reading Indoloquinoline Ligands Favor Intercalation at Quadruplex-Duplex Interfaces
2021 / PROTEIN SCIENCE
Forisomes are giant self-assembling mechanoproteins that undergo reversible structural changes in response to Ca2+ and various other stimuli. Artificial forisomes… Continue reading The Ca2+ response of a smart forisome protein is dependent on polymerization
2022 / ADVANCED FUNCTIONAL MATERIALS
Biophosphors with fluorescent proteins (FPs) are promising candidates to replace rare-earth color down-converting filters for white light-emitting diodes (LEDs). There… Continue reading Designing Artificial Fluorescent Proteins: Squaraine-LmrR Biophosphors for High Performance Deep-Red Biohybrid Light-Emitting Diodes
2022 / ADVANCED SCIENCE
Chiral organic ligand-incorporated low-dimensional metal-halide perovskites have received increasing attention for next-generation photodetectors because of the direct detection capability of… Continue reading Ultrasensitive Near-Infrared Circularly Polarized Light Detection Using 3D Perovskite Embedded with Chiral Plasmonic Nanoparticles
2022 / The EMBO Journal
Permeabilization of the outer mitochondrial membrane by pore-forming Bcl2 proteins is a crucial step for the induction of apoptosis. Despite… Continue reading High-resolution analysis of the conformational transition of pro-apoptotic Bak at the lipid membrane
2022 / Chirality
The ICD phenomenon has drawn a lot of attention in recent years in applicable fields such as chiral sensing and… Continue reading Tunable induced circular dichroism in gels
2022 / Nature Communications
Multi-component systems often display convoluted behavior, pathway complexity and coupled equilibria. In recent years, several ways to control complex systems… Continue reading Controlling the length of porphyrin supramolecular polymers via coupled equilibria and dilution-induced supramolecular polymerization
2022 / Nature Communications
Modified nucleotides in tRNAs are important determinants of folding, structure and function. Here we identify METTL8 as a mitochondrial matrix… Continue reading The RNA methyltransferase METTL8 installs m3C32 in mitochondrial tRNAsThr/Ser(UCN) to optimise tRNA structure and mitochondrial translation
2022 / Nature Communications
Rieske oxygenases exploit the reactivity of iron to perform chemically challenging C–H bond functionalization reactions. Thus far, only a handful… Continue reading Design principles for site-selective hydroxylation by a Rieske oxygenase
2022 / Nature Communications
The receptor binding domain (RBD) of the Spike protein from SARS-CoV-2 is a promising candidate to develop effective COVID-19 vaccines… Continue reading Hypocrates is a genetically encoded fluorescent biosensor for (pseudo)hypohalous acids and their derivatives
2022 / Scientific Reports
A method to produce hybrid organotitanias, both as thin films and suspensions, showing excellent photocatalyic activity in the degradation of… Continue reading Covalent coupling of Spike’s receptor binding domain to a multimeric carrier produces a high immune response against SARS-CoV-2
