2016 / Talanta
Metallothionein (MT) is a cysteine-rich, low-molecular-weight protein, which adopts a unique dumbbell-shaped structure with a stable C-terminal α-domain and a reactive… Continue reading Dumbbell-shaped metallothionein-templated silver nanoclusters with applications in cell imaging and Hg2+ sensing
2016 / Biochemical and Biophysical Research Communications
A hollow nanoparticle known as a bio-nanocapsule (BNC) consisting of hepatitis B virus (HBV) envelope L protein and liposome (LP)… Continue reading Mutational analysis of hepatitis B virus pre-S1 (9–24) fusogenic peptide
2016 / Food Chemistry
Recombinant ferrochelatase (BsFECH) from Bacillus subtilis expressed in Escherichia coli BL21(DE3) was found by UV-visible spectroscopy to bind the model substrate tetraphenylporphyrin-sulfonate, TPPS, with… Continue reading Limited Proteolysis of Myoglobin Opens Channel in Ferrochelatase-Globin Complex for Iron to Zinc Transmetallation
2016 / Biochimica et Biophysica Acta (BBA) - Bioenergetics
The Fenna–Matthews–Olson (FMO) pigment–protein complex in green sulfur bacteria transfers excitation energy from the chlorosome antenna complex to the reaction… Continue reading Perturbation Of Bacteriochlorophyll Molecules In Fenna-Matthews-Olson Protein Complexes Through Mutagenesis Of Cysteine Residues
2016 / Colloids and Surfaces A: Physicochemical and Engineer Aspects
Controlled compaction and decompaction of DNA by zwitterionic surfactants, alkyldimethylamine oxides (CnDMAO, n = 10, 12, and 14), were investigated by various… Continue reading Controlled compaction and decompaction of DNA by zwitterionic surfactants
2016 / Journal of Biotechnology
FGF-21 has become a potential drug candidate for the treatment of type 2 diabetes. Previous studies have demonstrated that PEGylation… Continue reading Pilot-scale production and characterization of PEGylated human FGF-21 analog
2016 / Structure
Escherichia coli possesses a number of specific K+ influx and efflux systems that maintain an appropriate intracellular K+ concentration. Although regulatory mechanisms have… Continue reading The Potassium Binding Protein Kbp Is a Cytoplasmic Potassium Sensor
2016 / Biochimica et Biophysica Acta (BBA) - General Subjects
Protein antigens are degraded by endosomal protease in antigen presentation cell. T cells recognize peptides derived from antigen proteins bound… Continue reading Relationship between the magnitude of IgE production in mice and conformational stability of the house dust mite allergen, Der p 2
2016 / Journal of Inorganic Biochemistry
Stable RNA triplexes play key roles in many biological processes, while triplexes are thermodynamically less stable than the corresponding duplexes… Continue reading Binding properties of ruthenium(II) complexes Ru(bpy) 2(ppn)]2 + and Ru(phen)2(ppn)]2 + with triplex RNA: As molecular “light switches” and stabilizers for poly(U)·poly(A)*poly(U) triplex
2016 / Journal of Pharmaceutical Analysis
The interaction of baicalein with bovine serum albumin (BSA) has been investigated with the help of spectroscopic and molecular docking… Continue reading Effects of urea, metal ions and surfactants on the binding of baicalein with bovine serum albumin
2016 / RSC Advances
A family of optically active helical vinyl polymers bearing N-heterocycle substituted BINOL derivatives was synthesized by free radical polymerization. Their structures… Continue reading Synthesis and properties of optically active helical polymers from (S)-3-functional-3′-vinyl-BINOL derivatives
2016 / Engineering in Life Sciences
Chondroitinase ABC Ι can promote the recovery of spinal cord injuries by depolimerization of glycosaminoglycans. However, low thermal stability is… Continue reading Optimization of conformational stability and catalytic efficiency in chondroitinase ABC Ι by protein engineering methods
2016 / Physical Chemistry Chemical Physics
The present work reports the effect of confinement, and temperature therein, on the conformational fluctuation dynamics of domain-I of human… Continue reading Startling Temperature Effect on Proteins when Confined: Single Molecular Level Behaviour of Human Serum Albumin in Reverse Micelle
2016 / The Journal of Physical Chemistry B
A series of thermoresponsive polypeptides has been synthesized using a methodology that allowed facile adjustment of side-chain functional groups. The… Continue reading Role of Side-Chain Molecular Features in Tuning Lower Critical Solution Temperatures (LCSTs) of Oligoethylene Glycol Modified Polypeptides
2016 / Journal of Porphyrins and Phthalocyanines
“Non-fluorescent” chlorophyll catabolites (NCCs) were named “rusty pigments” originally, as they easily oxidized to yellow chlorophyll catabolites (YCCs) and other… Continue reading Zn-complex of a natural yellow chlorophyll catabolite
2016 / Analytical Chemistry
Simple chiral recognition method of 2-alkylalcohols on a silica gel plate was proposed by using the induced circular dichroism (ICD)… Continue reading Chiral Recognition of 2-Alkylalcohols with Magnetic Circular Dichroism Measurement of Porphyrin J-Aggregate on Silica Gel Plate
2016 / RSC Advances
Clinical application of exenatide, a peptide drug widely used for the treatment of type 2 diabetes mellitus, is greatly limited… Continue reading Exenatide loaded PLGA microspheres for long-acting antidiabetic therapy: preparation, characterization, pharmacokinetics and pharmacodynamics
2016 / PNAS
The relationship between folding cooperativity and downhill, or barrier-free, folding of proteins under highly stabilizing conditions remains an unresolved topic,… Continue reading Cooperative folding near the downhill limit determined with amino acid resolution by hydrogen exchange
2016 / Scientific Reports
The STIL protein is essential for centriole replication and for the non-templated, de novo centriole biogenesis that is required for mammalian embryogenesis.… Continue reading Molecular basis of the STIL coiled coil oligomerization explains its requirement for de-novo formation of centrosomes in mammalian cells
2016 / Internation Journal of Biological Macromolecules
Various in vitro and in vivo studies have shown the anti-inflammatory and anticancer potential role of ethyl pyruvate. Bio-distribution of drugs is significantly influenced… Continue reading Accelerating full thickness wound healing using collagen sponge of mrigal fish (Cirrhinus cirrhosus) scale origin
