2016 / ChemBioChem
ATR-X (α-thalassemia/mental retardation X-linked) syndrome is caused by mutations in chromatin remodeler ATRX. ATRX can bind the variable number of… Continue reading Effect of ATRX and G-Quadruplex Formation by the VNTR Sequence on α-Globin Gene Expression
2016 / Drug Delivery
Surfactin, a natural lipopeptide produced by Bacillus, is gaining attention for potentially biomedical and pharmaceutical applications. Here, surfactin was assayed… Continue reading A natural lipopeptide of surfactin for oral delivery of insulin
2016 / Langmuir
A facile approach for the preparation of core–shell structured poly(acrylic acid) (PAA)-coated Fe3O4 cluster@SiO2 nanocomposite particles as the support materials for the… Continue reading Study of Molecular Conformation and Activity-Related Properties of Lipase Immobilized onto Core–Shell Structured Polyacrylic Acid-Coated Magnetic Silica Nanocomposite Particles
2016 / Macromolecule Chemistry and Physics
This article reports optically active helical polymers showing inverse helicity, which is controlled by copolymer composition. L-Proline-derived monomer and an… Continue reading Helical Polymers Showing Inverse Helicity and Synergistic Effect in Chiral Catalysis: Catalytic Functionality Determining Enantioconfiguration and Helical Frameworks Providing Asymmetric Microenvironment
2016 / FEBS Open Bio
Elevated reaction temperatures are crucial for the efficient enzymatic degradation of polyethylene terephthalate (PET). A disulfide bridge was introduced to… Continue reading A disulfide bridge in the calcium binding site of a polyester hydrolase increases its thermal stability and activity against polyethylene terephthalate
2016 / Carbohydrate Polymers
Homopolymannuronic and homopolyguluronic fractions were obtained by partial hydrolysis of the alkaline extracts from the brown seaweeds Ascoseira mirabilis, Desmarestia menziessi,… Continue reading Chiroptical characterization of homopolymeric block fractions in alginates
2016 / The Journal of Biological Chemistry
Although most proteins fold by populating intermediates, the transient nature of such states makes it difficult to characterize their structures.… Continue reading Identification and Structural Characterization of an Intermediate in the Folding of the Measles Virus X domain
2016 / Biotechnology for Biofuels
The conversion of biomass-derived sugars via enzymatic hydrolysis for biofuel production is a challenge. Therefore, the search for microorganisms and… Continue reading Crystal structure and biochemical characterization of the recombinant ThBgl, a GH1 β-glucosidase overexpressed in Trichoderma harzianum under biomass degradation conditions
2016 / Chemical Engineering Research and Design
Improving foam stability is an important issue in foam fractionation of proteins from their aqueous solutions with low foam properties.… Continue reading Enhancing protein self-association at the gas–liquid interface for foam fractionation of bovine serum albumin from its highly diluted solution
2016 / Ultrasonics Sonochemistry
The mechanism of ultrasound field promoting enzymolysis efficiency is difficult to study, because the reaction system mixes with enzymes, proteins… Continue reading Mechanism study of dual-frequency ultrasound assisted enzymolysis on rapeseed protein by immobilized Alcalase
2016 / The Journal of Biological Chemistry
A bioinformatics strategy was used to identify Scabin, a novel DNA-targeting enzyme from the plant pathogen 87.22 strain of Streptomyces scabies.… Continue reading Scabin, a novel DNA-acting ADP-ribosyltransferase from Streptomyces scabies
2016 / Scientific Reports
To combat infection and antimicrobial resistance, it is helpful to elucidate drug mechanism(s) of action. Here we examined how the… Continue reading The antimicrobial polymer PHMB enters cells and selectively condenses bacterial chromosomes
2016 / PNAS
The lysosomal integral membrane protein type-2 (LIMP-2) plays a pivotal role in the delivery of β-glucocerebrosidase (GC) to lysosomes. Mutations… Continue reading Characterization of the complex formed by β-glucocerebrosidase and the lysosomal integral membrane protein type-2
2016 / The Journal of Biological Chemistry
The first exon of the Huntingtin protein (Httex1) is one of the most actively studied Htt fragments because its overexpression… Continue reading An Intein-based Strategy for the Production of Tag-free Huntingtin Exon 1 Proteins enables New Insights into the PolyQ Dependence of Httex1 Aggregation and Fibril Formation
2016 / Journal of Materials Chemistry B
Supramolecular assembly to form a large variety of nanostructures has received increasing attention for diverse applications, in particular biomedical applications… Continue reading Reorganization of self-assembled supramolecular materials controlled by hydrogen bonding and hydrophilic–lipophilic balance
2016 / asia materials
The chiral nonanuclear Tb(III) clusters [Tb9(sal-(R)-Bt)16(μ-OH)10]+[NO3]−(Tb-(R)-Bt: sal-(R)-Bt=(R)-2-butyl salicylate) and [Tb9(sal-(S)-Bt)16(μ-OH)10]+[NO3]− (Tb-(S)-Bt: sal-(S)-Bt=(S)-2-butyl salicylate) were found to exhibit a unique magneto-optical property: the Faraday… Continue reading The relationship between magneto-optical properties and molecular chirality
2016 / Phytomedicine
Catharanthus roseus (L.) G. Don consists of a range of dimeric indole alkaloids with significant antitumor activities. These alkaloids have been… Continue reading Induction of apoptosis in human leukemia cells through an intrinsic pathway by cathachunine, a unique alkaloid isolated from Catharanthus roseus
2016 / Spectroscopy Letters
Various types of water-miscible aprotic ionic liquids (ILs) with different cations (1-ethyl-3-methylimidazolium, 1-butyl-3-methylimidazolium, 1-octyl-3-methylimidazolium) and anions (ethylsulfate and chloride) were… Continue reading Impact of imidazolium based ionic liquids on the structure and stability of lysozyme
2016 / Organic and Biomolecular Chemistry
In this study, we describe the thermal and optical properties of the thrombin binding aptamer (TBA) that has been modified… Continue reading Optimization of fluorescent 8-heteroaryl-guanine probes for monitoring protein-mediated duplex → G-quadruplex exchange
2016 / Scientific Reports
Amyloids are cross-β-sheet fibrillar aggregates, associated with various human diseases and native functions such as protein/peptide hormone storage inside secretory… Continue reading Amyloid formation of growth hormone in presence of zinc: Relevance to its storage in secretory granules
