2016 / Marine Drugs
Salterns, one of the most extreme natural hypersaline environments, are a rich source of halophilic and halotolerant microorganisms, but they… Continue reading New Cyclic Lipopeptides of the Iturin Class Produced by Saltern-DerivedBacillus sp. KCB14S006
2016 / Scientific Reports
TDP-43 is a DNA/RNA binding protein associated with TDP-43 proteinopathies. Many mutations have been identified in the flexible C-terminal region,… Continue reading Two mutations G335D and Q343R within the amyloidogenic core region of TDP-43 influence its aggregation and inclusion formation
2016 / Frontiers of Chemical Science and Engineering
MATTt (a thermostable methionine adenosyltransferase from Thermus thermophilusHB27) was overexpressed in Escherchia coli and purified using Ni-NTA affinity column. The enzymatic activity of… Continue reading Functional characterization of a thermostable methionine adenosyltransferase from Thermus thermophilus HB27
2016 / European Journal of Organic Chemistry
Strigolactones (SLs) constitute an important new class of plant hormones. Their isolation from natural resources, such as root exudates, is… Continue reading Securing Important Strigolactone Key Structures: Orobanchol and 5-Deoxystrigol
2016 / Methods in Enzymology
Rational approaches for the control of nano–bio interfaces for enzyme stabilization are vital for engineering advanced, functional nanobiocatalysts, biosensors, implants,… Continue reading Rationally Designed, “Stable-on-the-Table” NanoBiocatalysts Bound to Zr(IV) Phosphate Nanosheets
2016 / Scientific Reports
Psychrophilic enzymes evolved from a plethora of structural scaffolds via multiple molecular pathways. Elucidating their adaptive strategies is instrumental to… Continue reading Oligomerization as a strategy for cold adaptation: Structure and dynamics of the GH1 β-glucosidase from Exiguobacterium antarcticum B7
2016 / Biochemical and Biophysical Research Communications
In this study, we first report characterization of collagencin, an antimicrobial peptide identified from fish collagen hydrolysate. The peptide completely… Continue reading Collagencin, an antibacterial peptide from fish collagen: Activity, structure and interaction dynamics with membrane
2016 / Physical Chemistry Chemical Physics
Cis and trans proline conformers are often associated with dramatic changes in the biological function of peptides. A slow equilibrium between cis and trans Ile–Pro amide bond… Continue reading Proline cis-trans isomerization and its implications for the dimerization of analogues of cyclopeptide stylostatin 1: a combined computational and experimental study
2016 / The Journal of Biological Chemistry
Neuronal nitric-oxide synthase, unlike its endothelial and inducible counterparts, displays a PDZ (PSD-95/Dlg/ZO-1) domain located at its N terminus involved… Continue reading Insights into the C-terminal Peptide Binding Specificity of the PDZ domain of neuronal Nitric Oxide Synthase. Characterization of the Interaction with the tight-junction protein Claudin-3
2016 / Scientific Reports
Most stromal corneal dystrophies are associated with aggregation and deposition of the mutated transforming growth factor-β induced protein (TGFβIp). The… Continue reading pH Induced Conformational Transitions in the Transforming Growth Factor β-Induced Protein (TGFβIp) Associated Corneal Dystrophy Mutants
2016 / Protein Expression and Purification
Metal ion regulation is essential for living organisms. In prokaryotes metal ion dependent transcriptional factors, the so-called metalloregulatory proteins play… Continue reading Advanced purification strategy for CueR, a cysteine containing copper(I) and DNA binding protein
2016 / Food Hydrocolloids
The effect of the soybean lecithin (SL) (0–0.25% w/v) on the kinetics of whey protein (2% w/v) fibrils formation and their stability… Continue reading Formation and pH-stability of whey protein fibrils in the presence of lecithin
2016 / Polyhedron
To investigate the construction of novel chiral coordination polymers and the effect of different substituents on the ligands, three complexes,… Continue reading Syntheses, Structures and Catalytic Properties of Chiral Co(II) Coordination Polymers based on (R)-4-(4-(1-Carboxyethoxy)phenoxy)benzoic Acid
2016 / Internation Dairy journal
β-Lactoglobulin (β-lg) is a globular protein accounting for 11% of all milk proteins. Recently, the use of β-lg as vehicles… Continue reading Effect of various calcium concentrations on the interactions between β-lactoglobulin and epigallocatechin-3-gallate
2016 / Journal of Virology
The fusion peptides (FP) play an essential role in fusion of viral envelope with cellular membranes. The location and properties… Continue reading Identification of the Fusion Peptide-Containing Region in Betacoronavirus Spike Glycoproteins
2016 / Applied Microbial and Cell Physiology
As an alternative class of antimicrobial agents used to overcome drug-resistant infections, antimicrobial peptides (AMPs) have recently gained significant attention.… Continue reading K1K8: an Hp1404-derived antibacterial peptide
2016 / Archives of Biochemistry and Biophysics
Double stranded RNA (dsRNA) participates in several biological processes, where RNA molecules acquire secondary structure inside the cell through base… Continue reading dsRNA-protein interactions studied by molecular dynamics techniques. Unravelling dsRNA recognition by DCL1
2016 / Chemical Engineering Journal
Biodesulfurization has emerged as potential alternative to oxidative desulfurization and hydrodesulfurization. However, main impediment in commercial application of biodesulfurization process… Continue reading Physical Insight into Ultrasound-Assisted Biodesulfurization using Free and Immobilized Cells of Rhodococcus rhodochrous MTCC 3552
2016 / Colloids and Surfaces B: Biointerfaces
Bacterial resistance to antimicrobials is a global threat that requires development of innovative therapeutics that circumvent its onset. The use… Continue reading Interaction between a cationic bolaamphiphile and DNA: The route towards nanovectors for oligonucleotide antimicrobials
2016 / International Journal of Biological Macromolecules
Arginine (Arg) is one of the most versatile solvent additives, such as suppressing protein aggregation, increasing solubility of small aromatic… Continue reading Charge state of arginine as an additive on heat-induced protein aggregation
