2016 / RSC Advances
Besides being fundamental in the development of severe complications such as retinopathy, neuropathy and kidney disorders, non-enzymatic glycation also modulates… Continue reading Carbonyl scavenging and chemical chaperon like function of essential amino acids attenuates non-enzymatic glycation of albumin
2016 / RSC Advances
The present work deals with the synthesis and characterization of a novel nucleoamino acid derivative based on a L-tyrosine moiety to… Continue reading Solid phase synthesis of TyrT, a thymine–tyrosine conjugate with poly(A) RNA-binding ability
2016 / RSC Advances
We report for the first time the use of Nα-Boc-L-tryptophan for the synthesis of amphiphilic BAB triblock copolymers for potential… Continue reading Synthesis and self-assembly behaviour of poly(Nα-Boc-L-tryptophan)-block-poly(ethylene glycol)-block-poly(Nα-Boc-L-tryptophan)
2016 / Soft Matter
Three L-tartaric acid based symmetrical A–π–D-chiral-D–π–A type structural isomeric nitrobenzylidenes (1–3) have been synthesized with intent to achieve isomer specific metallogels… Continue reading Alkali base triggered intramolecular charge transfer metallogels based on symmetrical A–π–D-chiral-D–π–A type ligands
2016 / RSC Advances
The present work reports the construction of new Co-MOFs based on an amide based bispyrazole ligand and different carboxylic acids… Continue reading Design of chiral Co(II)-MOFs and their application in environmental remediation and waste water treatment
2016 / Chinese Chemical Letters
Two new harziane diterpenoids, named (9R,10R)-dihydro-harzianone (1) and harzianelactone (2), were isolated from the endophytic fungus Trichoderma sp. Xy24 by using various… Continue reading Two new diterpenoids from the endophytic fungus Trichodermasp. Xy24 isolated from mangrove plant Xylocarpus granatum
2016 / The Journal of General and Applied Microbiology
A large number of propeptide regions from various proteins have been identified which function as intramolecular chaperones and assist the… Continue reading Expression in Pichia pastoris and characterization of Rhizomucor miehei lipases containing a new propeptide region
2016 / Bioscience, Biotechnology, and Biochemistry
The high-affinity IgE Fc receptor (FcεRI) β chain acts as a signal amplifier through the immunoreceptor tyrosine-based activation motif in… Continue reading Analysis of the conformation and thermal stability of the high-affinity IgE Fc receptor β chain polymorphic proteins
2016 / Scientific Reports
Ligand binding to certain classes of G protein coupled receptors (GPCRs) stimulates the rapid synthesis of cAMP through G protein.… Continue reading Small Molecule Inhibited Parathyroid Hormone Mediated cAMP Response by N–Terminal Peptide Binding
2016 / Expert Opinion on Drug Delivery
Oral insulin administration suffers gastrointestinal tract (GIT) degradation and inadequate absorption from the intestinal epithelium resulting in poor bioavailability. This… Continue reading Enhancement of oral insulin bioavailability:In vitro and in vivo assessment of nanoporous stimuli-responsive hydrogel microparticles
2016 / The FEBS Journal
Trypanosomes that cause sleeping sickness endocytose apolipoprotein L1 (APOL1)-containing trypanolytic factors from human serum, leading to trypanolytic death through generation… Continue reading Structural characterization of the C-terminal coiled coil domains of wild-type and kidney disease associated mutants of Apolipoprotein L1
2016 / PLoS ONE
A global increase in invasive infections due to group A Streptococcus (S. pyogenes or GAS) has been observed since the 1980s, associated with emergence… Continue reading NAD+-Glycohydrolase Promotes Intracellular Survival of Group AStreptococcus
2016 / Archives of Toxicology
Chronic exposure to propiverine, a frequently prescribed pharmaceutical for treatment of overactive bladder and incontinence, provokes massive protein accumulation in… Continue reading Novel insights into renal d-amino acid oxidase accumulation: propiverine changes DAAO localization and peroxisomal size in vivo
2016 / Journal of Peptide Science
Antimicrobial peptides (AMPs) are components of the innate immune system and may be potential alternatives to conventional antibiotics because they… Continue reading Lipopolysaccharide-bound structure of the antimicrobial peptide cecropin P1 determined by nuclear magnetic resonance spectroscopy
2016 / Biochimica et Biophysica Acta-Proteins and Proteomics
Hypoxanthine phosphoribosyl transferase from Trypanosoma cruzi (TcHPRT) is a critical enzyme for the survival of the parasite. This work demonstrates that the… Continue reading The role of the C-terminal region on the oligomeric state and enzymatic activity of Trypanosoma cruzi hypoxanthine phosphoribosyl transferase
2016 / Food Chemistry
The goal of this study was to prepare and characterize α-lactalbumin (ALA)-catechin conjugates as a novel emulsifier in improving the… Continue reading Characterization of catechin-α-lactalbumin conjugates and the improvement in β-carotene retention in an oil-in-water nanoemulsion
2016 / International Journal of Biological Macromolecules
The Bacillus subtilis DP1 was isolated from poultry farm soil at Anand district, India. The highest enzyme production (379.65 U/ml) was obtained at… Continue reading A novel alkaline keratinase from Bacillus subtilis DP1 with potential utility in cosmetic formulation
2016 / Journal of Photochemistry and Photobiology B: Biology
Methylene blue is a phenothiazine agent, that possesses a diversity of biomedical and biological therapeutic purpose, and it has also… Continue reading Measuring the bioactivity and molecular conformation of typically globular proteins with phenothiazine-derived methylene blue in solid and in solution: A comparative study using photochemistry and computational chemistry
2016 / International Journal of Biological Macromolecules
Aiming to improve thermostability of the mesophilic xylanase A from Bacillus subtilis(XynA), five single mutants (S22E, S27E, N32D, N54E and N181R)… Continue reading THERMOSTABILIZATION OF Bacillus subtilis GH11 XYLANASE BY SURFACE CHARGE ENGINEERING
2016 / Archives of Biochemistry and Biophysics
Thermophilic l-arabinose isomerase (AI), which catalyzes the interconversion of l-arabinose and l-ribulose, can be used to produce d-tagatose, a sugar substitute, from d-galactose. Unlike mesophilic… Continue reading Structure of the thermophilic L-Arabinose isomerase from Geobacillus kaustophilus reveals metal-mediated intersubunit interactions for activity and thermostability
