2016 / Journal of Inorganic Biochemistry
The tachykinin neuropeptide, neurokinin B (NKB), belongs to a family of peptides having diverse roles in the brain. NKB, along… Continue reading Endocytosis of the tachykinin neuropeptide, neurokinin B, in astrocytes and its role in cellular copper uptake
2016 / International Journal of Biological Macromolecules
The high mobility group box 1 protein has been identified as a key player in chromatin homeostasis including transcription regulation,… Continue reading Structural aspects of the interaction of anticancer drug Actinomycin-D to the GC rich region of hmgb1 gene
2016 / Journal of Bioscience and Bioengineering
The present study aims at isolation, identification, characterization and prediction of three-dimensional molecular architecture of a proteolytic enzyme from the… Continue reading Isolation, characterization and molecular three-dimensional structural predictions of metalloprotease from a phytopathogenic fungus, Alternaria solani (Ell. and Mart.) Sor.
2016 / Data in Brief
Cellular homeostasis requires correct delivery of cell-surface receptor proteins (cargo) to their target subcellular compartments. The adapter proteins Tom1 and… Continue reading Structure of the GAT domain of the endosomal Q2 adapter protein Tom1
2016 / Journal of Structural Biology
Chemotaxis and motility play an important role in the colonisation of avian and human hosts by Campylobacter jejuni. Chemotactic recognition of… Continue reading The crystal structure of the tandem-PAS sensing domain of Campylobacter jejuni chemoreceptor Tlp1 suggests indirect mechanism of ligand recognition
2016 / European Journal of Pharmaceutical Sciences
Core-shell nanoparticles (CSNPs) were developed to get over therapeutic amount of kynurenic acid (KYNA) across the blood–brain barrier (BBB). Bovine… Continue reading Targeting of the kynurenic acid across the blood–brain barrier by core-shell nanoparticles
2016 / Process Biochemistry
The physicochemical properties and antioxidant activities of two fucosylated chondroitin sulfate (ACP and HOP) isolated from sea cucumber Acaudina molpadioidea andHolothuria nobilis respectively… Continue reading Physicochemical properties and antioxidant activities of two fucosylated chondroitin sulfate from sea cucumber Acaudina molpadioidea and Holothuria nobilis
2016 / Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
Icotinib is a highly-selective epidermal growth factor receptor tyrosine kinase inhibitor with preclinical and clinical activity in non-small cell lung… Continue reading Investigation on the protein-binding properties of icotinib by spectroscopic and molecular modeling method
2016 / Biochemistry
Energetic coupling of two molecular events in a protein molecule is ubiquitous in biochemical reactions mediated by proteins, such as… Continue reading Energetic Coupling between Ligand Binding and Dimerization inEscherichia coli Phosphoglycerate Mutase
2016 / PLoS ONE
This is the first report to provide comprehensive thermodynamic and structural data concerning duplex, hairpin, quadruplex and i-motif structures in… Continue reading Thermodynamic Features of Structural Motifs Formed by β-L-RNA
2016 / Biomacromolecules
There are four EF-hand polypeptides in calmodulin, a natural ubiquitous calcium binding protein that activates the enzymes involved in Ca2+-mediated… Continue reading EF-Hand Mimicking Calcium Binding Polymer
2016 / RSC Advances
Anstifolines A and B, two dimeric furoquinoline alkaloids with unique coupling patterns were isolated from the root bark of Dictamnus angustifolius.… Continue reading Anstifolines A and B, two dimeric furoquinoline alkaloids from the root bark of Dictamnus angustifolius
2016 / Fitoterapia
Three new clerodane type diterpenoids (2–4), together with one known analogues (1), were isolated from the tuberous roots of Tinospora sagittata (Oliv.)… Continue reading Clerodane-type diterpenoids from tuberous roots of Tinospora sagittata (Oliv.) Gagnep
2016 / Journal of Pharmaceutical Sciences
A specific covalently linked dimeric species of insulin high molecular weight products (HMWPs), formed during prolonged incubation of a neutral… Continue reading Structure, Aggregation, and Activity of a Covalent Insulin Dimer Formed During Storage of Neutral Formulation of Human Insulin
2016 / Journal of Raman Spectroscopy
Histidine has been shown to play a major role in a number of biological systems. Being able to understand unconstrained… Continue reading Probing conformational propensities of histidine in different protonation states of the unblocked glycyl-histidyl-glycine peptide by vibrational and NMR spectroscopy
2016 / Sensing and Bio-sensing Research
This study demonstrates the potential of porphyrin modified antimicrobial peptides for indication of bacterial targets on the basis of changes… Continue reading Porphyrin-modified antimicrobial peptide indicators for detection of bacteria
2016 / PLoS ONE
Fungal Cu-thioneins, and among them, the paradigmatic Neurospora crassa metallothionein (MT) (26 residues), were once considered as the shortest MTs -the ubiquitous,… Continue reading The Fungus Tremella mesenterica Encodes the Longest Metallothionein Currently Known: Gene, Protein and Metal Binding Characterization
2016 / Journal of Molecular Catalysis A: Chemical
A new artificial oxidase has been developed for selective transformation of thioanisole. The catalytic activity of an iron inorganic complex, FeLibu,… Continue reading Catalysis without a headache: Modification of ibuprofen for the design of artificial metalloenzyme for sulfide oxidation
2016 / Journal of the Iranian Chemical Society
Treatment of pyridine-2,6-dicarboxylic acid and 2-aminopyrimidine with Co(NO3)2∙6H2O under hydrothermal conditions led to a new Co (II) complex [Co(amp)(pydc)(H2O)2]∙H2O (1),… Continue reading Synthesis, characterization, cytotoxic activity and DNA-binding studies of cobalt (II) mixed-ligand complex containing pyridine-2,6-dicarboxylate ion and 2-aminopyrimidine
2016 / Antimicrobial Agens and Chemotherapy
Drug-resistant pathogens are a growing problem, and novel strategies are needed to combat this threat. Among the most significant of… Continue reading Combined Bioinformatic and Rational Design Approach to Develop Antimicrobial Peptides againstMycobacterium tuberculosis
