2016 / Biochemistry
Forkhead box P2 (FOXP2) is a transcription factor expressed in cardiovascular, intestinal, and neural tissues during embryonic development and is… Continue reading The effect of pH on the structure and DNA binding of the FOXP2 forkhead domain
2014 / Future Medicinal Chemistry
Antibiotic resistance has become a major health problem. The σ70:core interface of bacterial RNA polymerase is a promising drug target.… Continue reading Surface plasmon resonance – more than a screening technology: insights in the binding mode of σ70:core RNAP inhibitors
2015 / Biochemistry
Multidrug resistance against the existing antibiotics is becoming a global threat, and any potential drug that can be designed using… Continue reading Detergent-Type Membrane Fragmentation by MSI-78, MSI-367, MSI-594, and MSI-843 Antimicrobial Peptides and Inhibition by Cholesterol: A Solid-State Nuclear Magnetic Resonance Study
2015 / MRS Proceedings
We report optically active ensembles of II-VI semiconductor nanocrystals prepared via chiral phase transfer, which is initiated by exchange of… Continue reading Optically active II-VI semiconductor nanocrystals via chiral phase transfer
2015 / Food Biophysics
The role of Ca2+ in gelation of myosin extracted from silver carp (Hypophthalmichthys molitrix) was investigated. Compared with the control, myosin… Continue reading Ca2+ -Induced Conformational Changes of Myosin from Silver Carp (Hypophthalmichthys molitrix ) in Gelation
2015 / Soft Matter
A series of chiral aryl amide compounds bearing peptide pendants have been investigated as low molecular weight gelators. A mechanistic… Continue reading Multi-stimuli-responsive chiral organogels based on peptide derivatives
2015 / Metallomics
The human (h) ZIP4 transporter is a plasma membrane protein which functions to increase the cytosolic concentration of zinc. hZIP4… Continue reading The large intracellular loop of hZIP4 is an intrinsically disordered zinc binding domain
2015 / Colloids and Surfaces B: Biointerfaces
Graphene oxide nanosheet (GOns) with sharp edges was synthesized using controlled pyrolysis of citric acid. Scanning electron, as well as… Continue reading Bovine α-lactalbumin functionalized graphene oxide nano-sheet exhibits enhanced biocompatibility: A rational strategy for graphene-based targeted cancer therapy
2015 / ChemPlusChem
Folic acid has emerged as an interesting cell-targeting moiety and a number of drugs have been conjugated to folate. In… Continue reading Folate–Cyclodextrin Conjugates as Carriers of the Platinum(IV) Complex LA-12
2015 / RSC Advances
A large variety of cross-linked cyclodextrin polymers exhibiting interesting properties towards various guests have been characterized. Some polymeric nanoparticles based… Continue reading Novel amino-cyclodextrin cross-linked oligomer as efficient carrier for anionic drugs: a spectroscopic and nanocalorimetric investigation
2015 / RSC Advances
Novozyme435, which is a successfully commercialized biocatalyst, can efficiently catalyze the ring-opening polymerization (ROP) of lactones. However, for six-membered unsubstituted… Continue reading Coating Novozyme435 with an ionic liquid: more than just a coating for the efficient ring-opening polymerization of δ-valerolactone
2015 / Journal of Photopolymer Science and Technology
Active surface of luminescent silicon nanoparticles was terminated by the photochemical reaction of chiral molecules, (S)- or (R)-5-allyl-2-oxabicyclo[3,3,0]oct-8-ene ((S) –… Continue reading Luminescent Silicon Nanoparticles Surface-Modified with Chiral Molecules
2016 / The Journal of Physical Chemistry B
The structure and stability of biomolecules under molecular crowding conditions are of interest because such information clarifies how biomolecules behave… Continue reading Stabilization of DNA Structures with Poly(ethylene sodium phosphate)
2015 / Inorganica Chimica Acta
A new family of nickel–lanthanide heterometallic dinuclear complexes derived from a chiral Schiff-base ligand, (R,R)-N,N′-bis(3-methoxysalicylidene)cyclohexane-1,2-diamine (H2L), namely [Ni(L)Ln(NO3)3(H2O)] (Ln = Ce (1),… Continue reading A family of nickel–lanthanide heterometallic dinuclear complexes derived from a chiral Schiff-base ligand exhibiting single-molecule magnet behaviors
2015 / The Journal of Biological Chemistry
The N-terminal amino acid 1–83 fragment of apolipoprotein A-I (apoA-I) has a strong propensity to form amyloid fibrils at physiological… Continue reading Amyloidogenic Mutation Promotes Fibril Formation of the N-terminal Apolipoprotein A-I on Lipid Membranes
2006 / Journal of Photochemistry and Photobiology A: Chemistry
Mesophases composed of a nematic mixture (ZLI1132) alone or with a chiral inductor (twisted nematic phase) were doped with a… Continue reading Photoinduced changes of absorption and circular dichroism in a chiral nematic phase containing a photochromic fulgide
2005 / Analytical Biochemistry
To support drug discovery efforts for cyclin-dependent kinase 2 (CDK2), a moderate-throughput binding assay that can rank order or estimate… Continue reading Ligand binding affinity determined by temperature-dependent circular dichroism: Cyclin-dependent kinase 2 inhibitors
2006 / Biochimica et Biophysica Acta
Immobilised enzymes are widely used in industry, but the reasons for loss of activity of such biocatalysts are usually not… Continue reading Circular dichroism studies of subtilisin Carlsberg immobilised on micron sized silica particles
2006 / Biochimica et Biophysica Acta
The structural change of β-lactoglobulin A (βLG A) on heating was measured at pH 3.0 and 7.5 with UV absorption… Continue reading Effects of heating at neutral and acid pH on the structure of β-lactoglobulin A revealed by differential scanning calorimetry and circular dichroism spectroscopy
2006 / Molecular Genetics and Metabolism
The acyl-CoA dehydrogenases (ACDs) are a family of flavoenzymes involved in the metabolism of fatty acids and branched-chain amino acids.… Continue reading Functional analysis of acyl-CoA dehydrogenase catalytic residue mutants using surface plasmon resonance and circular dichroism
