ARC repressor (apoptosis repressor with caspase recruitment domain) is a protein which binds selectively to a specific sequence of DNA.… Continue reading Synthesis, Characterization, and DNA Binding Profile of a Macrocyclic β‑Sheet Analogue of ARC Protein
Leah Pandiscia, PhD
July 28, 2017
Peptides or peptide conjugates capable of assembling into one-dimensional (1D) nanostructures have been extensively investigated over the past two decades… Continue reading Electrostatic-Driven Lamination and Untwisting of β‑Sheet Assemblies
Leah Pandiscia, PhD
July 28, 2017
Deterministic placement and dynamic manipulation of individual plasmonic nanoparticles with nanoscale precision feature an important step toward active nanoplasmonic devices… Continue reading Optically Resolving the Dynamic Walking of a Plasmonic Walker Couple
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
The biological role of the existence of overlapping structures in RNA is possible yet remains very unexplored. G-Rich tracts of… Continue reading The RNA Stem−Loop to G‑Quadruplex Equilibrium Controls Mature MicroRNA Production inside the Cell
Leah Pandiscia, PhD
July 28, 2017
Protein–protein interactions are recognized as a fundamental phenomenon that is intimately associated with biological functions and thus are ideal targets… Continue reading Long-Range Communication Network in the Type 1B Bone Morphogenetic Protein Receptor
Leah Pandiscia, PhD
July 28, 2017
We investigate the effect of stretching on the secondary structure of cross-linked poly(l-lysine)/hyaluronic acid (PLL/HA) multilayers. We show that stretching… Continue reading Stretch-Induced Helical Conformations in Poly(L‑lysine)/Hyaluronic Acid Multilayers
Leah Pandiscia, PhD
July 28, 2017
Chiral DNA–silica hybrid free-standing films (CDSFs) with antipodal handedness were fabricated via the self-assembly of DNA and a silica source… Continue reading Optically Active Chiral DNA−Silica Hybrid Free-Standing Films
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
The synthesis and structural characterization of azahelicene platinum complexes obtained fromcis-PtCl2(NCEt)(PPh3) and from ligands that differ in terms of both… Continue reading Synthesis and Structural Properties of Aza[n]helicene Platinum Complexes: Control of Cis and Trans Stereochemistry
Leah Pandiscia, PhD
July 28, 2017
Protein phase behavior and protein–protein interactions can be tuned by additives. We experimentally determined the phase behavior of lysozyme solutions,… Continue reading Additivity of the Specific Effects of Additives on Protein Phase Behavior
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Design of a new catalytic function in proteins, apart from its inherent practical value, is important for fundamental understanding of… Continue reading New Tricks for Old Proteins: Single Mutations in a Nonenzymatic Protein Give Rise to Various Enzymatic Activities
Leah Pandiscia, PhD
July 28, 2017
MicroRNA (miRNA) biomarkers display great potential for cancer diagnosis and prognosis. The development of rapid and specific methods for miRNA… Continue reading Hairpin DNA-Templated Silver Nanoclusters as Novel Beacons in Strand Displacement Amplification for MicroRNA Detection
Leah Pandiscia, PhD
July 28, 2017
A pair of racemic indolizidine enantiomers, (±)-homocrepidine A (1), and a piperidine derivative, homocrepidine B (2), were isolated from Dendrobium crepidatum along… Continue reading (±)-Homocrepidine A, a Pair of Anti-inflammatory Enantiomeric Octahydroindolizine Alkaloid Dimers from Dendrobium crepidatum
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Eight non-carotenoid tetraterpenoids, abibalsamins C–J (3–10), were isolated from the oleoresin of Abies balsamea. Their chemical structures were determined based on… Continue reading DFT Calculations and ROESY NMR Data for the Diastereochemical Characterization of Cytotoxic Tetraterpenoids from the Oleoresin of Abies balsamea
Leah Pandiscia, PhD
July 28, 2017
Bioactivity-guided isolation of a methanolic extract of Euphorbia fischeriana led to the isolation of four new abietane-type diterpenoids, fischeriolides A–D (1–4), together… Continue reading Diterpenoids from the Roots of Euphorbia fischeriana with Inhibitory Effects on Nitric Oxide Production
Leah Pandiscia, PhD
July 28, 2017
Two new diterpenoid α-pyrones, named higginsianins A (1) and B (2), were isolated from the mycelium of the fungus Colletotrichum higginsianum grown… Continue reading Higginsianins A and B, Two Diterpenoid α‑Pyrones Produced by Colletotrichum higginsianum, with in Vitro Cytostatic Activity
Leah Pandiscia, PhD
July 28, 2017