Nineteen compounds mainly including pyrrole-containing alkaloids and phytosterols were isolated from the EtOH extract of the fermented mycelia of Xylaria nigripes,… Continue reading Chemical Constituents from the Fermented Mycelia of the Medicinal Fungus Xylaria nigripes
Leah Pandiscia, PhD
July 28, 2017
Single step elution of a protein A column with 100 mM acetate pH 3.5 produced a curvilinear gradient with pH dropping… Continue reading Conformational plasticity of IgG during protein A affinity chromatography
Leah Pandiscia, PhD
July 28, 2017
Influence of surface charge, binding site residues and glycosylation on Thielavia terrestris cutinase biochemical characteristics
Leah Pandiscia, PhD
July 28, 2017
The topological study of novel quadruplex-forming DNA sequences found in immunoglobulin switch regions Sμ and Sγ3 is described along with… Continue reading Stabilization of novel immunoglobulin switch regions G-quadruplexes by naphthalene and quinoline-based ligands
Leah Pandiscia, PhD
July 28, 2017
The adaptor protein 4 (AP4) complex (ϵ/β4/μ4/σ4 subunits) forms a non-clathrin coat on vesicles departing the trans-Golgi network. AP4 biology remains… Continue reading Molecular basis for the interaction between Adaptor Protein Complex 4 (AP4) β4 and its accessory protein, tepsin
Leah Pandiscia, PhD
July 28, 2017
We report the preparation of biocompatible, dual stimuli-sensitive lipoic acid-modified poly(l-lysine) (PLL-g-Lipo) hydrogels/nanogels by chemical cross-link and polypeptide/silica hybrid hydrogels/nanogels… Continue reading Redox- and pH-Sensitive Lipoic Acid-Modified Poly(L-lysine) and Polypeptide/Silica Hybrid Hydrogels/Nanogels
Leah Pandiscia, PhD
July 28, 2017
A new natural product, designated iminimycin A, was isolated from the cultured broth of a streptomycin-producing microbial strain, Streptomyces griseus… Continue reading Iminimycin A, the new iminium metabolite produced by Streptomyces griseus OS-3601
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
TRAM domain proteins present in Archaea and Bacteria have a β-barrel shape with anti-parallel β-sheets that form a nucleic acid binding surface; a structure… Continue reading Single TRAM domain RNA-binding proteins in Archaea: functional insight from Ctr3 from the Antarctic methanogen Methanococcoides burtonii 1
Leah Pandiscia, PhD
July 28, 2017
A chiral tetraphenylethene derivative with two valine-containing attachments (TPE-DVAL), was synthesized by Cu(I)-catalyzed azide-alkyne “click” reaction. The optical properties and… Continue reading Synthesis, optical properties, and helical self-assembly of a bivalinecontaining tetraphenylethene
Leah Pandiscia, PhD
May 24, 2018
Anti-inflammatory coumarins with short- and long-chain hydrophobic groups from roots of Angelica dahurica cv. Hangbaizhi
Leah Pandiscia, PhD
July 28, 2017
This study addressed the effect of contact sliding during stirring of a monoclonal antibody solution on protein aggregation, in particular,… Continue reading No Touching! Abrasion of Adsorbed Protein Is the Root Cause of Subvisible Particle Formation During Stirring
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
This study reports a method for the facile and high-yield exfoliation of WX2 (X = S, Se) by sonication under aqueous… Continue reading DNA-Assisted Exfoliation of Tungsten Dichalcogenides and Their Antibacterial Effect
Leah Pandiscia, PhD
July 28, 2017
Chirality is a highly important topic in modern chemistry, given the dramatically different pharmacological effects that enantiomers can have on… Continue reading Hydrogen-Regulated Chiral Nanoplasmonics
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
We discovered the unique cell adhesive properties of ultraviolet (UV)-irradiated albumin films. Albumin films prepared using a cross-linking reagent with… Continue reading Changes in Cell Adhesiveness and Physicochemical Properties of Cross-Linked Albumin Films after Ultraviolet Irradiation
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
The synthesis of multicomponent superhelices with determined chirality has been realized. By adding water to polymer solution in organic solvents… Continue reading Superhelices with Designed Helical Structures and Temperature-Stimulated Chirality Transitions
Leah Pandiscia, PhD
July 28, 2017
The adaptive property of supramolecular building blocks facilitates noncovalent synthesis of soft materials. While it is still a challenging task,… Continue reading Superstructure Formation and Topological Evolution Achieved by Self-Organization of a Highly Adaptive Dynamer
Leah Pandiscia, PhD
July 28, 2017