2020 / Sensors and Actuators B: Chemical
The split G-quadruplex/hemin DNAzyme exhibits peroxidase-like activity and catalyzes the oxidation of colorless 2,2′-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS2−) to the green-colored… Continue reading Use of Tris-NH4Cl in modified G4/hemin DNAzyme assay with duplexed probes extends life of colorized radical product
2020 / Food Chemistry
The self-microemulsifying delivery system was fabricated by whey protein isolate (WPI), daidzein (Dai) and surfactants, the interaction of WPI, Dai… Continue reading Interaction among protein, daidzein and surfactants in the WPI-based daidzein self-microemulsifying delivery system
2020 / Journal of Structural Biology
Plakophilin 1 (PKP1) is a member of the armadillo repeat family of proteins. It serves as a scaffold component of… Continue reading The isolated armadillo-repeat domain of Plakophilin 1 is a monomer in solution with a low conformational stability
2020 / Biotechnology Letters
Acute lymphoblastic leukaemia (ALL) affects lymphoblastic cells and is the most common neoplasm during childhood. Among the pharmaceuticals used in… Continue reading Functional and structural evaluation of the antileukaemic enzyme L-asparaginase II expressed at low temperature by different Escherichia coli strains
2020 / Physical Chemistry Chemical Physics
The use of cosolvents and high hydrostatic pressure (HHP) has been described as an efficient means to modulate the stability… Continue reading The Multifaceted Effects of DMSO and High Hydrostatic Pressure on the Kinetic Constants of Hydrolysis Reactions Catalyzed by α-Chymotrypsin
2020 / Methods and Applications in Fluorescence
DNA-DNA reactions can be monitored with a label-free fluorogenic reaction. Guanosine-rich, single-stranded DNA oligonucleotides bind to thioflavin-T (ThT) and enhance… Continue reading Thioflavin T as a noncovalent reporter for a label-free, non-enzymatic, catalytic DNA amplifier
2020 / Biochimica et Biophysica Acta (BBA) - General Subjects
Bacterial microcompartment represents the only reported category of prokaryotic organelles that are capable of functioning as independent bioreactors. In this… Continue reading Probe into a multi-protein prokaryotic organelle using thermal scanning assay reveals distinct properties of the core and the shell
2020 / Scientific Reports
Human pancreatic islet amyloid polypeptide (hIAPP) and beta amyloid (Aβ) can accumulate in Type 2 diabetes (T2D) and Alzheimer’s disease (AD)… Continue reading Amylin and beta amyloid proteins interact to form amorphous heterocomplexes with enhanced toxicity in neuronal cells
2020 / Scientific Reports
A bpss2242 gene, encoding a putative short-chain dehydrogenase/oxidoreductase (SDR) in Burkholderia pseudomallei, was identified and its expression was up-regulated by ten-fold when B. pseudomallei was… Continue reading Functional analysis of BPSS2242 reveals its detoxification role in Burkholderia pseudomallei under salt stress
2020 / ACS Omega
A novel Entadin lectin was isolated, purified, and characterized from the seeds of Entada rheedii by ammonium sulfate precipitation, followed by lactose… Continue reading Biochemical Characterization of Lactose Binding Entadin Lectin from Entada rheedii Seeds with Cytotoxic Activity against Cancer Cell Lines
2020 / The FEBS Journal
To survive in cold environments, psychrophilic organisms produce enzymes endowed with high specific activity at low temperature. The structure of… Continue reading The co‐existence of cold activity and thermal stability in an Antarctic GH42 β‐galactosidase relies on its hexameric quaternary arrangement
2020 / Redox Biology
Anastellin (AN), a fragment of the first type III module in fibronectin (FN), initiates formation of superfibronectin, a polymer which… Continue reading Peroxynitrous acid (ONOOH) modifies the structure of Anastellin and influences its capacity to polymerize fibronectin
2020 / Journal of Molecular Structure
Monosodium glutamate (MSG) is an example of food additive, which is used as a flavor enhancer in various foodstuffs. Because… Continue reading Thermodynamic analysis of albumin interaction with monosodium glutamate food additive: Insights from multi-spectroscopic and molecular docking approaches
2020 / Biochimica et Biophysica Acta (BBA) - General Subjects
Fungal aryl-alcohol oxidases (AAOx) are extracellular flavoenzymes that belong to glucose-methanol-choline oxidoreductase family and are responsible for the selective conversion… Continue reading Enzymatic versatility and thermostability of a new aryl-alcohol oxidase from Thermothelomyces thermophilus M77
2020 / Food Research International
In recent years, almond has been considered as one of the most common alternative plant-based protein sources due to its… Continue reading Effect of pulsed ultrasound, a green food processing technique, on the secondary structure and in-vitro digestibility of almond milk protein
2020 / PLOS Neglected Tropical Diseases
In Brazil, Plasmodium vivax infection accounts for around 80% of malaria cases. This infection has a substantial impact on the productivity of… Continue reading Plasmodium vivax AMA1: Implications of distinct haplotypes for immune response
2020 / Biomacromolecules
How to control osteochondral differentiation of mesenchymal stem cells at a proper stage is a key issue for articular cartilage… Continue reading Thermogelling Inclusion Complex System for Fine-Tuned Osteochondral Differentiation of Mesenchymal Stem Cells
2020 / Journal of Biological Chemistry
Rapid clearance by renal filtration is a major impediment to the translation of small bioactive biologics into drugs. To extend… Continue reading Structure-activity analysis of truncated albumin-binding domains suggests new lead constructs for potential therapeutic delivery
2020 / Journal of Drug Delivery Science and Technology
In the present study, a novel amphiphilic short peptide KHHAAAAAAA (abbreviated as KHHA7) and reference peptides were synthesized as dispersants… Continue reading Development of amphiphilic metal-binding short peptides that change the dispersibility of paclitaxel upon complexation with intermediate metal(II) ions
2020 / Journal of Natural Products
Triple-negative breast cancers (TNBC) are aggressive and heterogeneous cancers that lack targeted therapies. We implemented a screening program to identify… Continue reading Triple-Negative Breast Cancer Cells Exhibit Differential Sensitivity to Cardenolides from Calotropis gigantea
