2020 / molecules
G-quadruplex specific targeting molecules, also termed as G4 ligands, are attracting increasing attention for their ability to recognize and stabilize… Continue reading The Interaction of Cyclic Naphthalene Diimide with G-Quadruplex under Molecular Crowding Condition
2020 / Biochimica et Biophysica Acta (BBA) - General Subjects
Enzymatic isomerization is a promising strategy to solve the problem of xylose fermentation and, consequently, to leverage the production of… Continue reading Crystal structure of a novel xylose isomerase from Streptomyces sp. F-1 revealed the presence of unique features that differ from conventional classes
2020 / bioRxiv
Acetyl-CoA synthetase (ACS) is one of several enzymes that generate the key metabolic intermediate, acetyl-CoA. In microbial cells ACS generates… Continue reading Modulation of plant Acetyl CoA Synthetase activity by acetylation
2020 / Inorganic Chemistry
Manganese porphyrins are used as catalysts in the oxidation of olefins and nonactivated hydrocarbons. Key to these reactions are high-valent… Continue reading Elucidating the Electronic Structure of High-Spin [MnIII(TPP)Cl] Using Magnetic Circular Dichroism Spectroscopy
2020 / Protein Expression and Purification
Antibodies that block interaction of immune checkpoint receptors with its ligands have revolutionized the treatment of several cancers. Despite the… Continue reading Initial development of biosimilar immune checkpoint blockers using HEK293 cells
2020 / ACS Nano
The selective interplay between dimensional morphology transition and signal transfer is an important feature for both nanomaterials and biosystems. While… Continue reading Dimension-Tunable Circularly Polarized Luminescent Nanoassemblies with Emerging Selective Chirality and Energy Transfer
2020 / Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
Increased Pur-alpha (Pura) protein levels in animal models alleviate certain cellular symptoms of the disease spectrum amyotrophic lateral sclerosis/frontotemporal dementia… Continue reading A synthetic Pur-based peptide binds and alters G-quadruplex secondary structure present in the expanded RNA repeat of C9orf72 ALS/FTD
2020 / International Journal of Biological Macromolecules
As ubiquitous environmental pollutants, phenolic compounds are requested to be efficiently removed from wastewater. Enzymes, such as Horseradish peroxidase (HRP),… Continue reading Nanocapsulation of horseradish peroxidase (HRP) enhances enzymatic performance in removing phenolic compounds
2020 / Biomaterials
As ubiquitous environmental pollutants, phenolic compounds are requested to be efficiently removed from wastewater. Enzymes, such as Horseradish peroxidase (HRP),… Continue reading Mesoporous polydopamine with built-in plasmonic core: Traceable and NIR triggered delivery of functional proteins
2020 / Bioorganic Chemistry
Three new nardosinane-type sesquiterpenoids linardosinenes A–C (1–3) and four new neolemnane-type sesquiterpenoids lineolemnenes A–D (4–7), together with the related known… Continue reading Uncommon nornardosinane, seconeolemnane and related sesquiterpenoids from Xisha soft coral Litophyton nigrum
2020 / Molecular Immunology
Mus m 1.0102 is a member of the mouse Major Urinary Protein family, belonging to the Lipocalins superfamily. Major Urinary… Continue reading The allergen Mus m 1.0102: Cysteine residues and molecular allergology
2020 / Inorganic Chemistry
Protein aggregation has attracted substantial interest because of its role in causing many serious illnesses, such as neurodegenerative diseases and… Continue reading Copper(II) and Amylin Analogues: A Complicated Relationship
2020 / Food Chemistry
Arthrospira platensis, commonly known as Spirulina, gains increasing importance as alternative protein source for food production and biotechnological systems. A promising… Continue reading Time-temperature-resolved functional and structural changes of phycocyanin extracted from Arthrospira platensis/Spirulina
2020 / Biochemistry
Cleavage and polyadenylation specificity factor 30 (CPSF30) is a “zinc finger” protein that plays a crucial role in the transition… Continue reading Unraveling the RNA Binding Properties of the Iron–Sulfur Zinc Finger Protein CPSF30
2020 / Scientific Reports
Biosynthesis of hydrogen sulfide (H2S), a key signalling molecule in human (patho)physiology, is mostly accomplished by the human enzymes cystathionine… Continue reading Screening Pyridine Derivatives against Human Hydrogen Sulfide-synthesizing Enzymes by Orthogonal Methods
2020 / Proteins
We investigated the structure and Brownian rotational motion of the PEST region (201‐268) from human c‐Myc oncoprotein, whose overexpression/dysregulation is… Continue reading Structure and dynamics at N‐ and C‐terminal regions of intrinsically disordered human c‐Myc PEST degron reveal a pH‐induced transition
2020 / International Journal of Biological Macromolecules
Peroxiredoxin 6 (Prdx6) is a ubiquitously expressed 1-cysteine Peroxiredoxin found throughout all phyla. In mammals, under different physiological conditions, it… Continue reading The anti-oxidant enzyme, Prdx6 might have cis-acting regulatory sequence(s)
2020 / applied sciences
Ultrasonic pulses are considered green technology for the improvement of the functional properties of proteins. In this study, four high-intensity… Continue reading High-Intensity Ultrasound Pulses Effect on Physicochemical and Antioxidant Properties of Tilapia (Oreochromis niloticus) Skin Gelatin
2020 / Chemical and Pharmaceutical Bulletin
An ion-channel-forming natural peptide, gramicidin A (1), exhibits potent antimicrobial activity against Gram-positive bacteria, although medical applications are limited to… Continue reading Phospholipid-Dependent Functions of a Macrocyclic Analogue of the Ion-Channel-Forming Antibiotic Gramicidin A
2020 / Food Chemistry
The inhibitory mechanisms of ferulic acid against α-amylase and α-glucosidase were investigated by enzyme kinetic analysis, circular dichroism (CD), Fourier-transform… Continue reading Inhibition mechanism of ferulic acid against α-amylase and α-glucosidase
