2019 / Microchimica Acta
Gold nanoclusters (Au NCs) using fibrinogen (FBG) protein as template are fabricated via one-pot reduction strategy, and applied for fluorometric… Continue reading Fibrinogen-templated gold nanoclusters for fluorometric determination of cysteine and mercury(II)
2020 / LWT
The study investigated effects of gallic acid (GA, 0, 1, 5, 25 and 125 μmol/g) on properties of oxidatively stressed Japanese… Continue reading Dose affected the role of gallic acid on mediating gelling properties of oxidatively stressed Japanese seerfish myofibrillar protein
2019 / International Journal of Biological Macromolecules
Do kidney osmolytes counteract the deleterious effects of urea on kidney proteins? To answer this question, we measured guanidinium chloride… Continue reading Urea Stress: Myo-inositol’s efficacy to counteract destabilization of TIM-β-globin complex by urea is as good as that of the methylamine
2020 / Materials & Design
Self-assembling peptides (SAPs) show great promise in regenerative medicine and beyond. Yet, their low mechanical rigidity and limited processability hinder… Continue reading Characterization of elastic, thermo-responsive, self-healable supramolecular hydrogel made of self-assembly peptides and guar gum
2019 / International Journal of Biological Macromolecules
The emergence and spread of multidrug-resistant strains of Klebsiella pneumoniae is a major concern that necessitates the development of unique therapeutics. The… Continue reading Allosteric inhibition and kinetic characterization of Klebsiella pneumoniae CysE: An emerging drug target
2020 / Journal of Inorganic Biochemistry
This work presents the synthesis and characterization of eight copper complexes [Cu(L-dipeptide)(neo)]·nH2O (neo = neocuproine) and their cytotoxic activities against tumor cell… Continue reading Synthesis and structural characterization of a series of ternary copper(II)-L-dipeptide-neocuproine complexes. Study of their cytotoxicity against cancer cells including MDA-MB-231, triple negative breast cancer cells☆
2019 / Nucleic Acids Research
BMVC is the first fluorescent probe designed to detect G-quadruplexes (G4s) in vivo. The MYC oncogene promoter forms a G4 (MycG4)… Continue reading Structures of 1:1 and 2:1 complexes of BMVC and MYC promoter G-quadruplex reveal a mechanism of ligand conformation adjustment for G4-recognition
2019 / International Journal of Biological Macromolecules
Inhibition of collagen fibrillation by small molecules is of growing interest to develop therapeutics for the illnesses related to excess… Continue reading N-Vanillylnonanamide, a natural product from capsicum oleoresin, as potential inhibitor of collagen fibrillation
2019 / Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
This paper proposes the idea of establishing carbendazim (CBZ) colorimetric determination in spiked water samples by specific aptamers of unlabeled… Continue reading Colorimetric determination of carbendazim based on the specific recognition of aptamer and the poly-diallyldimethylammonium chloride aggregation of gold nanoparticles
2020 / Protein Expression and Purification
Cysteine-rich secretory protein 4 (CRISP4) is a member of the CAP superfamily protein, is highly expressed in the male reproductive… Continue reading Expression and purification of recombinant mouse CRISP4 using a baculovirus system
2020 / Toxicology Letters
The clinical drug-drug interactions mediated by heterotropic activation on cytochrome P450 (CYP450) kinetics, especially CYP3A4, have received wide concern in… Continue reading Heterotropic activation of flavonoids on cytochrome P450 3A4: A case example of alleviating dronedarone-induced cytotoxicity
2019 / Bioprocess and Biosystems Engineering
Activation and stabilization of enzymes is an important issue in their industrial application. We recently reported that synthetic betaines, derived… Continue reading Structural effect of amine N-oxides on the facilitation of α-glucosidase-catalyzed hydrolysis reactions
2019 / Monatshefte für Chemie - Chemical Monthly
The interaction of a nucleoside analogue bromodeoxyuridine (BrdU) with human serum albumin (HSA) was studied to investigate the binding phenomenon… Continue reading Biophysical and computational approaches to unravel the molecular interaction mechanism of bromodeoxyuridine, a proliferative marker with human serum albumin
2019 / Langmuir
Due to the unique optical properties of gold nanomaterials, the preparation of gold nanomaterials with excellent chirality has received extensive… Continue reading Self-assembled peptide functionalized gold nanopolyhedrons with excellent chiral optical properties
2019 / Molecular Cell
Lipid droplets (LDs) provide a reservoir for triacylglycerol storage and are a central hub for fatty acid trafficking and signaling… Continue reading Lipid Droplet-Derived Monounsaturated Fatty Acids Traffic via PLIN5 to Allosterically Activate SIRT1
2020 / International Journal of Molecular Sciences
Cloxyquin is a potential therapeutic compound possessing various bioactivities, especially antibacterial, antifungal, cardioprotective, and pain relief activities. Herein, the interaction… Continue reading Insight into the Molecular Interaction of Cloxyquin (5-chloro-8-hydroxyquinoline) with Bovine Serum Albumin: Biophysical Analysis and Computational Simulation
2019 / International Journal of Biological Macromolecules
The Hsp70 family of heat shock proteins plays a critical function in maintaining cellular homeostasis within various subcellular compartments. The… Continue reading Thermal aggregates of human mortalin and Hsp70-1A behave as supramolecular assemblies
2019 / Protein Expression and Purification
5′- nucleotidase (5′-NT) is a key enzyme in nucleoside/nucleotide metabolic pathway, it plays an important role in the biosynthesis of… Continue reading Expression, purification and characterization of 5′-nucleotidase from caterpillar fungus by efficient genome-mining
2019 / Scientific Reports
Delivery of the theranostic agents with effective concentration to the desired sites inside the body is a major challenge in… Continue reading Protease Responsive Essential Amino-Acid Based Nanocarriers for Near-Infrared Imaging
2019 / ACS Catalysis
The heterogeneous asymmetric hydrogenation of quinolines for the production of optically active tetrahydroquinoline derivatives still remains a difficult task due… Continue reading Efficient Asymmetric Hydrogenation of Quinolines over Chiral Porous Polymers Integrated with Substrate Activation Sites
