The effects of a single-amino-acid culture strategy on secondary metabolite production in the marine-derived fungus Trichoderma erinaceum F1-1 were investigated by culturing… Continue reading l-Phenylalanine Alters the Privileged Secondary Metabolite Production in the Marine-Derived Fungus Trichoderma erinaceum F1-1
Leah Pandiscia, PhD
March 24, 2020
Ovine β‑lactoglobulin was characterized by spectroscopic (CD), calorimetric (ITC) and X-ray structural studies. The structure of ovine β‑lactoglobulin complex with… Continue reading Conformational flexibility and ligand binding properties of ovine β-lactoglobulin
Leah Pandiscia, PhD
March 24, 2020
Leah Pandiscia, PhD
March 24, 2020
Silk fibroin (SF) hydrogels have been engineered as universal substrates for various tissue regenerations and drug delivery. Although different physical… Continue reading Amorphous Silk Fibroin Nanofiber Hydrogels with Enhanced Mechanical Properties
Leah Pandiscia, PhD
March 24, 2020
Leah Pandiscia, PhD
March 24, 2020
Leah Pandiscia, PhD
March 24, 2020
We present SEM, ThT fluorescence and circular dichroism (CD) data of amyloidogenic aggregates of cytochrome c (cyt c).This protein is of outmost relevance… Continue reading Cytochrome c aggregation: A dataset at and far from the isoelectric point
Leah Pandiscia, PhD
March 24, 2020
In this work, we develop a drug-mimicking nanofibrous peptide hydrogel that shows long-term bioactivity comparable to a small-molecule inhibitor of… Continue reading Drug-Mimicking Nanofibrous Peptide Hydrogel for Inhibition of Inducible Nitric Oxide Synthase
Leah Pandiscia, PhD
March 24, 2020
Whey protein nanostructures can be used as vehicles for the incorporation of nutraceuticals (e.g., antioxidants or vitamins) aimed at the… Continue reading Physicochemical characterisation and release behaviour of curcumin-loaded lactoferrin nanohydrogels into food simulants
Leah Pandiscia, PhD
March 24, 2020
The pathogenesis of fatal neurodegenerative prion diseases is closely associated with the conversion of α-helix-rich cellular prion protein into β-sheet-rich… Continue reading Biophysical characterization of oligomerization and fibrillization of the G131V pathogenic mutant of human prion protein
Leah Pandiscia, PhD
March 24, 2020
Leah Pandiscia, PhD
March 24, 2020
Leah Pandiscia, PhD
March 24, 2020
In this study, we performed an ultraviolet‐visible (UV‐Vis) and circular dichroism (CD) spectroscopic analysis of the binary and ternary supramolecular… Continue reading Spectroscopic study of porphyrin self‐assembly: Role of pH, time, and chiral template
Leah Pandiscia, PhD
March 24, 2020
Leah Pandiscia, PhD
March 24, 2020
Solution stability of food proteins is a crucial factor determining their shelf-life and sensory properties; yet to obtain stable protein… Continue reading Preheat-stabilized pea proteins with anti-aggregation properties
Leah Pandiscia, PhD
March 24, 2020
Leah Pandiscia, PhD
March 24, 2020
Environmental factors like ionizing radiation induced generation of reactive oxygen species (ROS) cause macromolecular damage under physiological conditions. Proteins are… Continue reading Protection by ethyl pyruvate against gamma radiation induced damage in bovine serum albumin
Leah Pandiscia, PhD
March 24, 2020
Interaction of copper(II) and nickel(II) ions with the Ac-PHAAAGTHSMKHM-NH2 tridecapeptide containing the His85, His96 and His111 binding sites of human prion… Continue reading Complex formation processes and metal ion catalyzed oxidation of model peptides related to the metal binding site of the human prion protein
Leah Pandiscia, PhD
March 24, 2020
Superoxide dismutases (SODs) are highly efficient enzymes for superoxide dismutation and the first line of defense against oxidative stress. These… Continue reading Rational De Novo Design of a Cu Metalloenzyme for Superoxide Dismutation
Leah Pandiscia, PhD
March 24, 2020
Three new phenolic glycosides were isolated from the leaves and twigs of Magnolia figo, and identitified to be 3,4-dihydroxy-β-phenylethoxyl-O-[β-D-glucopyranosyl-(1″→2′)-α-L-rhamnopyranosyl-(1′”→3′)-(4′-O-trans-caffeoyl)-β-D-glucopyranosyl-(1′””→6′)]-β-D-glucopyranoside (champikhaekoside, 8), 4-hydroxybenzyl O-β-D-apiofuranosyl-(1″→2′)-[β-D-glucopyranosyl-(1′”→3′)]-β-D-glucopyranoside… Continue reading Phenolic glycosides from Magnolia figo
Leah Pandiscia, PhD
March 24, 2020