2019 / Tetrahedron Letters
Two novel 6,7-secoeunicellins, cladieunicellins W (1) and X (2), along with a known eunicellin, klymollin Y (3), were isolated from… Continue reading Novel secoeunicellins produced by an octocoral Cladiella sp
2019 / biomolecules
A novel dermaseptin peptide, dermaseptin-PT9 (DPT9), was isolated and identified from Phyllomedusa tarsius by the combination of molecular cloning and LC-MS analysis.… Continue reading A Novel Dermaseptin Isolated from the Skin Secretion of Phyllomedusa tarsius and Its Cationicity-Enhanced Analogue Exhibiting Effective Antimicrobial and Anti-Proliferative Activities
2019 / Journal of Organic Chemistry
Many synthetic and supramolecular chiral polymeric systems are known to exhibit the “majority rules effect” (MRE), a positive nonlinear response… Continue reading Design of Chiral Supramolecular Polymers Exhibiting a Negative Nonlinear Response
2019 / Colloids and Surfaces B: Biointerfaces
Supramolecular gel material built from low-molecular-weight (LMW) gelators finds potential applications in various fields, especially in drug delivery, cell encapsulation… Continue reading Non-proteinogenic amino acid based supramolecular hydrogel material for enhanced cell proliferation
2019 / Scientific Reports
Targeting bacterial virulence factors directly provides a new paradigm for the intervention and treatment of bacterial diseases. Pseudomonas aeruginosa produces a myriad… Continue reading Human single-chain antibodies that neutralize Pseudomonas aeruginosa-exotoxin A-mediated cellular apoptosis
2019 / Metallomics
The ferric ion binding protein A of Thermus thermophilus HB8 (TtFbpA) is the periplasmic subunit of an ABC-type iron transporter. Two Fe3+-bound… Continue reading Functional characterisation of two ferric-ion coordination modes of TtFbpA, the periplasmic subunit of an ABC-type iron transporter from Thermus thermophilus HB8
2020 / Phytochemistry
Cyclin dependent kinase A; 1 (CDKA; 1) is essential in G1/S transition of cell cycle and its oxidation has been… Continue reading Oxidation of proline from the cyclin-binding motif in maize CDKA;1 results in lower affinity with its cyclin regulatory subunit
2019 / RSC Advances
Since Ln-CPs have excellent optical properties (higher color purity, longer fluorescence lifetime and higher quantum yield) and magnetic properties, it… Continue reading Three chiral one-dimensional lanthanide–ditoluoyl-tartrate bifunctional polymers exhibiting luminescence and magnetic behaviors
2019 / Journal of Biological Chemistry
The second WW domain (WW2) of the kidney and brain scaffolding protein, KIBRA, has an isoleucine (Ile-81) rather than a… Continue reading Intrinsic disorder and amino acid specificity modulate binding of the WW2 domain in kidney and brain protein (KIBRA) to synaptopodin
2019 / Communications Biology
Amyloid formation is a process involving interconverting protein species and results in toxic oligomers and fibrils. Aggregated alpha-synuclein (αS) participates… Continue reading Alpha-synuclein stepwise aggregation reveals features of an early onset mutation in Parkinson’s disease
2019 / ACS Chemical Biology
Protein–protein interactions that can be controlled by environmental triggers have immense potential in various biological and industrial applications. In the… Continue reading Histidine-Mediated Intramolecular Electrostatic Repulsion for Controlling pH-Dependent Protein–Protein Interaction
2019 / Toxins
Immunotoxins are chimeric molecules that combine the specificity of an antibody to recognize and bind tumor antigens with the potency… Continue reading Inclusion of a Furin Cleavage Site Enhances Antitumor Efficacy against Colorectal Cancer Cells of Ribotoxin α-Sarcin-or RNase T1-Based Immunotoxins
2020 / Food Chemistry
The protective mechanism of glycerol on β-lactoglobulin were studied in 0–60% glycerol solutions by experimental and molecular simulation approaches. Results… Continue reading Glycerol induced stability enhancement and conformational changes of β-lactoglobulin
2020 / Radiation Physics and Chemistry
This paper investigated the functions of electron beam irradiation at doses of 1–9 kGy on the IgG binding capacity and the… Continue reading Studying on the IgG binding capacity and conformation of tropomyosin in Ovalipes punctatus meat irradiated with electron beam
2019 / Archives of Biochemistry and Biophysics
The Staphylococcus aureus Extracellular Adherence Protein (Eap) and its homologs, EapH1 and EapH2, are a family of secreted proteins that potently inhibit the neutrophil… Continue reading Staphylococcus aureus evasion proteins EapH1 and EapH2: Residue-level investigation of an alternative binding motif for human neutrophil elastase
2020 / Journal of Photochemistry and Photobiology A: Chemistry
In this manuscript we present a spectroscopic study of the supramolecular interaction of photo-switchable 4,4′-Azobenzene dicarboxylic acid (ADA) with L… Continue reading Spectroscopic study of the pH dependent interaction of an achiral molecular photo-switch with poly-Glutamic acid
2019 / Bioorganic & Medicinal Chemistry
Epirubicin exerts its anti cancer action by blocking DNA/RNA synthesis and inhibition of topoisomerase-II enzyme. Recent reports on its influence… Continue reading Dual mode of binding of anti cancer drug epirubicin to G-quadruplex [d-(TTAGGGT)]4 containing human telomeric DNA sequence induces thermal stabilization
2020 / Food Chemistry
The effects of low frequency magnetic field on myoglobin (Mb) oxidation stability were evaluated by treatments at 0, 3, 6,… Continue reading Effects of low frequency magnetic field on myoglobin oxidation stability
2020 / Colloids and Surfaces B: Biointerfaces
A peptide (FFACD) can form hydrogels in DMSO-H2O mixtures (G1), NaOH (G2) and L-arginine (G3) aqueous solutions, respectively. Methyl thiazolyl… Continue reading Peptide-assembled hydrogels for pH-controllable drug release
2019 / ACS Omega
The bacterial RNA polymerase is a multi-subunit enzyme complex composed of six subunits, α2ββ’σω. The function of this enzyme is… Continue reading Unraveling the Role of Silent Mutation in the ω-Subunit of Escherichia coli RNA Polymerase: Structure Transition Inhibits Transcription
