Biochemical study of type I collagen purified from skin of warm sea teleost Mahi mahi (Coryphaena hippurus), with a focus on thermal and physical stability

2019 / Journal of Food Chemistry

Acid‐ and pepsin‐soluble collagen were purified from the skin of mahi mahi (mmASC and mmPSC). The Pro+Hyp content of the… Continue reading Biochemical study of type I collagen purified from skin of warm sea teleost Mahi mahi (Coryphaena hippurus), with a focus on thermal and physical stability

Heather Haffner

Biophysical characterization of the breast cancer-related BIG3-PHB2 interaction: Effect of non-conserved loop region of BIG3 on the structure and the interaction

2019 / Biochemical and Biophysical Research Communications

Brefeldin A-inhibited guanine nucleotide-exchange protein 3 (BIG3) interacts with and inhibits the tumor suppressor function of prohibitin-2 (PHB2), and recent… Continue reading Biophysical characterization of the breast cancer-related BIG3-PHB2 interaction: Effect of non-conserved loop region of BIG3 on the structure and the interaction

Heather Haffner

Depsidones and a dihydroxanthenone from the endophytic fungi Simplicillium lanosoniveum (J.F.H. Beyma) Zare & W. Gams PSU-H168 and PSU-H261

2019 / Fitoterpia

Three new compounds including two depsidones (simplicildones J and K) and one dihydroxanthenone (globosuxanthone E) together with nine known compounds… Continue reading Depsidones and a dihydroxanthenone from the endophytic fungi Simplicillium lanosoniveum (J.F.H. Beyma) Zare & W. Gams PSU-H168 and PSU-H261

Heather Haffner

Exploring oxidovanadium(iv) homoleptic complexes with 8-hydroxyquinoline derivatives as prospective antitrypanosomal agents

2019 / New Journal of Chemistry

Ten structurally related homoleptic complexes, including three new compounds, were synthesized: five [VIVO(L-H)2] and five [VVO(OCH3)(L-H)2] compounds, where L–H =… Continue reading Exploring oxidovanadium(iv) homoleptic complexes with 8-hydroxyquinoline derivatives as prospective antitrypanosomal agents

Heather Haffner

Novel 4-quinoline-thiosemicarbazone derivatives: Synthesis, antiproliferative activity, in vitro and in silico biomacromolecule interaction studies and topoisomerase inhibition

2019 / European Journal of Medicinal Chemistry

Twelve 2-(quinolin-4-ylmethylene) hydrazinecarbothioamide derivatives were synthetized and their biological properties were investigated, among which, the ability to interact with DNA… Continue reading Novel 4-quinoline-thiosemicarbazone derivatives: Synthesis, antiproliferative activity, in vitro and in silico biomacromolecule interaction studies and topoisomerase inhibition

Heather Haffner

Synthesis and chemical properties of conjugated polymers with bis(trifluoromethanesulfonyl)imide and bis(nonafluorobutanesulfonyl)imide anions

2019 / European Polymer Journal

The reaction of N-(2,4-dinitrophenyl)pyridinium chloride (salt(Cl−)) with lithium bis(trifluoromethanesulfonyl)imide (TFSI−LI+) and lithium bis(nonafluorobutanesulfonyl)imide (NFSI−LI+) resulted in the anion exchange between Cl− and… Continue reading Synthesis and chemical properties of conjugated polymers with bis(trifluoromethanesulfonyl)imide and bis(nonafluorobutanesulfonyl)imide anions

Heather Haffner

Perturbation of tubulin structure by stellate gold nanoparticles retards MDA-MB-231 breast cancer cell viability

2019 / Journal of Biological Inorganic Chemistry

Gold nanoparticles (GNPs) of different sizes and shapes have been investigated extensively for their therapeutic potential against several diseases including cancer. However,… Continue reading Perturbation of tubulin structure by stellate gold nanoparticles retards MDA-MB-231 breast cancer cell viability

Heather Haffner

Integrated system for temperature-controlled fast protein liquid chromatography. III. Continuous downstream processing of monoclonal antibodies

2019 / Journal of Chromatography A

Three different applications of travelling heating zone reactor (THZR) chromatography for the downstream processing of monoclonal antibodies (mAbs) are described.… Continue reading Integrated system for temperature-controlled fast protein liquid chromatography. III. Continuous downstream processing of monoclonal antibodies

Heather Haffner