Anuran amphibian skin secretions are a rich source of peptides, many of which represent novel protease inhibitors and can potentially… Continue reading Discovery and Rational Design of a Novel Bowman-Birk Related Protease Inhibitor
Heather Haffner
November 13, 2019
In the present study, we investigate degradable anionic dendritic nanogels (DNG) as carriers for antimicrobial peptides (AMPs). In such systems,… Continue reading Degradable dendritic nanogels as carriers for antimicrobial peptides
Heather Haffner
November 13, 2019
A glycoside hydrolase family 5 (GH5) subfamily 22 gene, designated T81Xyl5_22A, was identified in the genome of the aerobic thermophilic… Continue reading A novel thermostable GH5 β-xylosidase from Thermogemmatispora sp. T81
Heather Haffner
November 13, 2019
Interaction studies of haemoglobin (Hb) with p-sulfonatocalix[8]arene (p-SCX8) has been analysed through UV–visible, fluorescence and circular dichroism spectroscopy. The Ch-π, π-π… Continue reading Interaction studies of haemoglobin with p-sulfonatocalix[8]arene by spectrophotometric methods
Heather Haffner
November 13, 2019
Sodium Deoxycholate (NaDC) and Phenylalanine (Phe) are important biological hydrogelators. NaDC hydrogels form by lowering the pH or by increasing… Continue reading Deoxycholic acid and l-Phenylalanine enrich their hydrogel properties when combined in a zwitterionic derivative
Heather Haffner
November 13, 2019
Heather Haffner
November 13, 2019
A diblock copolymer consists of ε-caprolactone, and tetrahydrofuran was synthesized by using a novel natural amino acids such as penicillamine… Continue reading Synthesis, characterization and applications of nano-Ag-tagged poly(ε-caprolactone-block-tetrahydrofuran)
Heather Haffner
November 13, 2019
Three new diterpenoid alkaloids, designated naviconine (1), naviculine (2) and naviconitine (3), together with five known diterpenoid alkaloids (4)–(8) were isolated… Continue reading Three new diterpenoid alkaloids from Delphinium naviculare var. lasiocarpum W. T. Wang
Heather Haffner
June 29, 2020
Oleandrin, the major biologically active constituent of shrub Nerium oleanderpreparations of which have been used in traditional Mediterranean and Asian medicine,… Continue reading Synthesis and evaluation of cytotoxic and Na+/K+-ATP-ase inhibitory activity of selected 5α-oleandrigenin derivatives
Heather Haffner
November 13, 2019
Heather Haffner
November 13, 2019
Smart delivery of therapeutic peptides that target cellular signaling pathways holds high specificity and great promise for cancer therapy. Here,… Continue reading Polypeptide-engineered DNA tetrahedrons for targeting treatment of colorectal cancer viaapoptosis and autophagy
Heather Haffner
November 13, 2019
Evidence suggests that amyloid fibril mitigation/inhibition is considered a promising approach toward treating amyloid diseases. In this work, we first… Continue reading Exploring the influence of brilliant blue G on amyloid fibril formation of lysozyme
Heather Haffner
November 13, 2019
Heather Haffner
November 13, 2019
Nowadays, the researchers make a big effort to find new alternatives to overcome bacterial drug resistance. One option is the… Continue reading The influence of cationic dendrimers on antibacterial activity of phage endolysin against P. aeruginosa cells
Heather Haffner
November 13, 2019
Polysaccharides with different structures have been reported to regulate iron uptake in opposite direction. The present study investigated the interaction… Continue reading A sulfated polysaccharide from abalone influences iron uptake by the contrary impacts of its chelating and reducing activities
Heather Haffner
November 13, 2019
During carcinogenesis, changes in the glycosylation can modulate many biological processes. Thus, the interest in exploring and understanding the roles… Continue reading Evaluating the glycophenotype on breast cancer tissues with quantum dots-Cramoll lectin conjugates
Heather Haffner
November 13, 2019
Nucleic acid aptamers can specifically bind to target molecules on the cell membrane that mediate their entrance into the cells.… Continue reading AS1411 derivatives as carriers of G-quadruplex ligands for cervical cancer cells
Heather Haffner
November 13, 2019
Oleosomes are subcellular organelles present naturally in plant seeds for storing lipids. Oleosomes can be used in the preparation of… Continue reading Thermally treated soya bean oleosomes: the changes in their stability and associated proteins
Heather Haffner
November 13, 2019
Aggregation of lens protein is a major cause of senile cataract. Lens crystallins contain many kinds of modification that accumulate… Continue reading Negative charge at aspartate 151 is important for human lens αA-crystallin stability and chaperone function
Heather Haffner
October 29, 2019
Protein secondary structures are frequently assessed using infrared and circular dichroism spectroscopies during drug development (e.g. during product comparability and/or… Continue reading Determining Spectroscopic Quantitation Limits for Misfolded Structures
Heather Haffner
September 25, 2019