2019 / Protein: Structure, Function, Bioinformatics
Many protein and peptide sequences are self‐assembled into β‐sheet‐rich fibrous structures called amyloids. Their atomic details provide insights into fundamental… Continue reading Grafting a short chameleon sequence from αB crystallin into a β‐sheet scaffold protein
2019 / Faraday Discussions
The sugar-phosphate backbone of DNA near single-stranded (ss)—double-stranded (ds) junctions likely fluctuates within a broad distribution of conformations to permit… Continue reading Measuring local conformations and conformational disorder of (Cy3)2 dimer labeled DNA fork junctions using absorbance, circular dichroism and two-dimensional fluorescence spectroscopy
2019 / ACS Nano
In this work, lanthanide-doped upconversion nanoparticles (UCNPs) showing upconverted circularly polarized luminescence were demonstrated in an organic–inorganic co-assembled system. Achiral… Continue reading Optically Active Upconverting Nanoparticles with Induced Circularly Polarized Luminescence and Enantioselectively Triggered Photopolymerization
2019 / Protein: Structure, Function, Bioinformatics
Small heat shock proteins (sHsps) are molecular chaperones employed to interact with a diverse range of substrates as the first… Continue reading Chaperone‐like activity of the N‐terminal region of a human small heat shock protein and chaperone‐functionalized nanoparticles
2019 / Nucleic Acids Research
It is essential to study RNA under molecular crowding conditions to better predict secondary structures of RNAs in vivo. No systematic… Continue reading Thermodynamic characterization and nearest neighbor parameters for RNA duplexes under molecular crowding conditions
2019 / RSC Advances
Seven undescribed phenylspirodrimane derivatives, stachybochartins A–G (1–7), and four known analogues (8–11) were isolated from the endophytic fungus Stachybotrys chartarum obtained from Pinellia… Continue reading Seven new cytotoxic phenylspirodrimane derivatives from the endophytic fungus Stachybotrys chartarum
2019 / RSC Advances
Chiral carbon quantum dots (CQDs) with chirality, fluorescence and biocompatibility were synthesized by a one-step method with L-/D-tryptophan (L-/D-Trp), as both… Continue reading Investigation on the chirality mechanism of chiral carbon quantum dots derived from tryptophan
2019 / International Journal of Nanomedicine
Fungal keratitis is a major cause of corneal blindness accounting for more than one-third of microbiologically proven cases. The management… Continue reading Designing and enhancing the antifungal activity of corneal specific cell penetrating peptide using gelatin hydrogel delivery system
2019 / Nucleic Acids Research
The yeast Nhp6A protein (yNhp6A) is a member of the eukaryotic HMGB family of chromatin factors that enhance apparent DNA… Continue reading Evidence for a bind-then-bend mechanism for architectural DNA binding protein yNhp6A
2019 / RSC Advances
Arsenic (As) is a toxic metalloid that has drawn immense attention from the scientific community recently due to its fatal… Continue reading Interaction landscape of a ‘CαNN’ motif with arsenate and arsenite: a potential peptide-based scavenger of arsenic
2019 / Bioconjugate Chemistry
Adhesion promoting peptides have been reported to enable efficient enzyme immobilization on various material surfaces. Here we report the first… Continue reading Anchor Peptide-Mediated Surface Immobilization of a Grubbs-Hoveyda-Type Catalyst for Ring-Opening Metathesis Polymerization
2019 / RSC Advances
Solid-state organic fluorescent materials are important for the development of electroluminescent sensing devices. Herein, we report that N,N′-bis((R)-1-phenylethyl)perylene-3,4,9,10-tetracarboxylic diimide [(R,R)-BPP] and… Continue reading Solid-state AIEnh-circularly polarised luminescence of chiral perylene diimide fluorophores
2019 / Metallomics
Here, we report the preparation and photo-physical characterization of hexa-coordinated vertebrate globins, human neuroglobin (hNgb) and cytoglobin (hCygb), with the… Continue reading Utility of fluorescent heme analogue ZnPPIX to monitor conformational heterogeneity in vertebrate hexa-coordinated globins
2019 / JACS
The recently discovered Rrf2 family transcriptional regulator RsrR coordinates a [2Fe–2S] cluster. Remarkably, binding of the protein to RsrR-regulated promoter… Continue reading Crystal Structure of the Transcription Regulator RsrR Reveals a [2Fe–2S] Cluster Coordinated by Cys, Glu, and His Residues
2019 / Investigational New Drugs
Thiosemicarbazone is a class of compounds with potential applications in medicine, presenting high capacity to inhibit the growth of cancer… Continue reading In vitro and in vivo cytotoxic activity and human serum albumin interaction for a methoxy-styryl-thiosemicarbazone
2019 / Journal of Peptide Science
The placental growth factor (PlGF), a member of VEGF family, plays a crucial role in pathological angiogenesis, especially ischemia, inflammation,… Continue reading Short PlGF‐derived peptides bind VEGFR‐1 and VEGFR‐2 in vitro and on the surface of endothelial cells
2019 / Biomacromolecules
Nature has developed different protein mediated mechanisms to remodel cellular membranes. One of the proteins that is implicated in these… Continue reading Cooperation of helix insertion and lateral pressure to remodel membranes
2019 / Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
Subcutaneous insulin delivery serves as the major treatment for the ever-increasing spread of type II diabetes worldwide. However, long-term exposure to insulin… Continue reading Sequence specificity of amylin-insulin interaction: a fragment-based insulin fibrillation inhibition study
2019 / Microbial Cell Factories
Pichia pastoris (syn. Komagataella phaffii) is one of the most highly utilized eukaryotic expression systems for the production of heterologous… Continue reading Recombinant O-mannosylated protein production (PstS-1) from Mycobacterium tuberculosis in Pichia pastoris (Komagataella phaffii) as a tool to study tuberculosis infection
2019 / The Journal of Physical Chemistry B
One of the most stable quadruplexes is formed by the G3T sequence (GGGTGGGTGGGTGGG) that folds into a parallel quadruplex with… Continue reading Stability Factors of the Parallel Quadruplexes: DNA Versus RNA
