2021 / Nature Communications
The post-translational modification of proteins with ubiquitin (Ub) and Ub-like modifiers (Ubls) represents one of the most important regulators in… Continue reading A modular toolbox to generate complex polymeric ubiquitin architectures using orthogonal sortase enzymes
2021 / Scientific Reports
Quenchbody (Q-body) is a quench-based fluorescent immunosensor labeled with fluorescent dye(s) near the antigen-binding site of an antibody. Q-bodies can… Continue reading Evaluation and selection of potent fluorescent immunosensors by combining fluorescent peptide and nanobodies displayed on yeast surface
2021 / Nature Communications
Lysocin E is a lipopeptide with antibiotic activity against methicillin-resistant Staphylococcus aureus. For unclear reasons, the antibacterial activity of lysocin… Continue reading Serum apolipoprotein A-I potentiates the therapeutic efficacy of lysocin E against Staphylococcus aureus
2021 / Scientific reports
The cellular prion protein (PrPC) is a mainly α-helical 208-residue protein located in the pre- and postsynaptic membranes. For unknown… Continue reading Zn(II) binding causes interdomain changes in the structure and flexibility of the human prion protein
2021 / Scientific reports
The structures of a cyanophage small heat shock protein (sHSP) were determined as octahedrons of 24-mers and 48-mers and as… Continue reading Multiple nanocages of a cyanophage small heat shock protein with icosahedral and octahedral symmetries
2021 / Scientific reports
Adjuvant-aided combination chemotherapy is one of the most effective ways of cancer treatment by overcoming the multidrug resistance (MDR) and… Continue reading Co-delivery of doxorubicin and conferone by novel pH-responsive β-cyclodextrin grafted micelles triggers apoptosis of metastatic human breast cancer cells
2021 / Scientific Reports
The concept of Molecular Crowding depicts the high density of diverse molecules present in the cellular interior. Here, we determine… Continue reading Impact of crowded environments on binding between protein and single-stranded DNA
2021 / nanomaterials
A chiral molecular gelation system, as a chiral host, was used to effectively realize enantioselectivity using the simple carboxylic acid… Continue reading Enantioselective Self-Assembled Nanofibrillar Network with Glutamide-Based Organogelator
2021 / Scientific Reports
Molybdenum (Mo) impregnated g-C3N4 (Mo-CN) nanotubes are fabricated via a thermal/hydrothermal process to augment photoelectrochemical properties during solar-driven water-splitting (SDWS)… Continue reading Molybdenum impregnated g-C3N4 nanotubes as potentially active photocatalyst for renewable energy applications
2021 / nanomaterials
Herein, we describe the synthesis of highly emissive amphiphilic N-annulated PBI 1 decorated with oligo ethylene glycol (OEG) side chains.… Continue reading Globular Aggregates Stemming from the Self-Assembly of an Amphiphilic N-Annulated Perylene Bisimide in Aqueous Media
2021 / Nature Communications
Most biological and synthetic receptors for small organic molecules employ a combination of relatively weak intermolecular interactions such as hydrogen… Continue reading Molecular recognition by multiple metal coordination inside wavy-stacked macrocycles
2021 / Scientific reports
Colistin resistance is complex and multifactorial. DbcA is an inner membrane protein belonging to the DedA superfamily required for maintaining… Continue reading A link between pH homeostasis and colistin resistance in bacteria
2021 / Nature Communications
Membrane contact sites (MCS) are subcellular regions where two organelles appose their membranes to exchange small molecules, including lipids. Structural… Continue reading Nanoscale architecture of a VAP-A-OSBP tethering complex at membrane contact sites
2021 / Nature Communications
Fluorogenic RNA aptamers are synthetic functional RNAs that specifically bind and activate conditional fluorophores. The Chili RNA aptamer mimics large… Continue reading Large Stokes shift fluorescence activation in an RNA aptamer by intermolecular proton transfer to guanine
2021 / Scientific Report
The glucocorticoid receptor is a key regulator of essential physiological processes, which under the control of the Hsp90 chaperone machinery,… Continue reading Glucocorticoid resistance conferring mutation in the C-terminus of GR alters the receptor conformational dynamics
2021 / Nature Communications
Biological membranes play pivotal roles in the cellular activities. Transmembrane proteins are the central molecules that conduct membrane-mediated biochemical functions… Continue reading A synthetic ion channel with anisotropic ligand response
2020 / Photochemical and Photobiological Sciences
We demonstrate amyloid fibril (AF) decomposition induced by NIR-active upconversion nanoparticles complexed with photosensitisers. The process is triggered by upconversion,… Continue reading Decomposition of amyloid fibrils by NIR-active upconversion nanoparticles
2021 / Nature Communications
Most archaea divide by binary fission using an FtsZ-based system similar to that of bacteria, but they lack many of… Continue reading SepF is the FtsZ anchor in archaea, with features of an ancestral cell division system
2021 / Scientific Report
The Pacific oyster, Crassostrea gigas, is a traditional food worldwide. The soft body of the oyster can easily accumulate heavy… Continue reading Identification and functional analysis of cadmium-binding protein in the visceral mass of Crassostrea gigas
2021 / Nature Communications
Overtemperature-protection intelligent molecular chiroptical photoswitches
