Development and validation of a stability-indicating lc method for the determination of tenofovir disoproxil fumarate in pharmaceutical formulation

2012 / Songklanakarin Journal of Science and Technology

The present study describes the degradation of tenoforvir disoproxil fumarate (teno) under different prescribed stress conditions (hydrolysis, oxidation, dry and… Continue reading Development and validation of a stability-indicating lc method for the determination of tenofovir disoproxil fumarate in pharmaceutical formulation

DJ Tognarelli

Development and Validation of LC Method for the Simultaneous Estimation of Rosuvastatin Calcium and Olmesartan Medoxomil in Pharmaceutical Dosage Form

2014 / International Journal of ChemTech Research

A simple, fast, and precise reverse phase, isocratic HPLC method was developed for the separation and quantification of Rosuvastatin calcium… Continue reading Development and Validation of LC Method for the Simultaneous Estimation of Rosuvastatin Calcium and Olmesartan Medoxomil in Pharmaceutical Dosage Form

DJ Tognarelli

DEVELOPMENT AND VALIDATION OF LC METHOD FOR THE SIMULTANEOUS ESTIMATION OF ROSIGLITAZONE MALEATE AND GLIMEPIRIDE IN PHARMACEUTICAL DOSAGE FORM

2012 / Malaysian Journal of Pharmaceutical Sciences

A simple, precise and accurate high performance liquid chromatography (HPLC) method was developed for simultaneous quantitative determination of rosiglitazone maleate… Continue reading DEVELOPMENT AND VALIDATION OF LC METHOD FOR THE SIMULTANEOUS ESTIMATION OF ROSIGLITAZONE MALEATE AND GLIMEPIRIDE IN PHARMACEUTICAL DOSAGE FORM

DJ Tognarelli

DEVELOPMENT AND VALIDATION OF A RP – LC METHOD FOR DISSOLUTION TEST OF EFAVIRENZ TABLETS AND ITS APPLICATION TO DRUG QUALITY CONTROL STUDIES

2013 / Asian Journal of Pharmaceutical and Clinical Research

A liquid chromatographic method is developed to evaluate a new dissolution profile of Efavirenz in tablet dosage form. The dissolution… Continue reading DEVELOPMENT AND VALIDATION OF A RP – LC METHOD FOR DISSOLUTION TEST OF EFAVIRENZ TABLETS AND ITS APPLICATION TO DRUG QUALITY CONTROL STUDIES

DJ Tognarelli

A validated stability indicating RP-HPLC method for valganciclovir, identification and characterization of forced degradation products of valganciclovir using LC-MS/MS

2014 / Acta Chromatographica

The objective of the present study was to report the stability of novel antiviral drug, valganciclovir based on the information… Continue reading A validated stability indicating RP-HPLC method for valganciclovir, identification and characterization of forced degradation products of valganciclovir using LC-MS/MS

DJ Tognarelli

A Validated Stability Indicating RP-HPLC Method for Nabumetone, Identification and Characterization of Forced Degradation Products of Nabumetone Using LC-MS/MS

2013 / Asian Journal of Chemistry

The objective of the present study was to report the stability of novel non-steroidal antiinflammatory drug (NSAID), nabumetone based on… Continue reading A Validated Stability Indicating RP-HPLC Method for Nabumetone, Identification and Characterization of Forced Degradation Products of Nabumetone Using LC-MS/MS

DJ Tognarelli

Peak decay analysis and biointeraction studies of immunoglobulin binding and dissociation on protein G affinity microcolumns

2018 / Methods, Volume 146, 15 August 2018, Pages 39-45

Protein G can be a valuable binding agent for antibodies and immunoglobulins in methods such as immunosensors, chromatographic-based immunoassays, and… Continue reading Peak decay analysis and biointeraction studies of immunoglobulin binding and dissociation on protein G affinity microcolumns

DJ Tognarelli

Enantiomeric impurity analysis using circular dichroism spectroscopy with United States Pharmacopeia liquid chromatographic methods

2018 / Journal of Pharmaceutical and Biomedical Analysis

Over 300 chiral drug substances lack official United States Pharmacopeia (USP) methods for the enantiomeric purity determination. Because enantiomeric analysis… Continue reading Enantiomeric impurity analysis using circular dichroism spectroscopy with United States Pharmacopeia liquid chromatographic methods

Leah Pandiscia, PhD