An oxidative cross-coupling strategy for quinoline ring annulation in Cinchonaalkaloids has been developed. Key-reaction optimization by changing oxidants and adjusting the nucleophilicity… Continue reading Expansion of the aromatic part of Cinchona alkaloids. Annulation of quinolines with phenoxazine motifs
Leah Pandiscia, PhD
October 11, 2018
Leah Pandiscia, PhD
October 11, 2018
Leah Pandiscia, PhD
October 11, 2018
This study demonstrated that incorporation of Ca2+-responsive β-roll peptides arising from repeat-in-toxin (RTX) into elastomeric proteins provided an approach to… Continue reading Using single molecule force spectroscopy to facilitate a rational design of Ca2+-responsive β-roll peptide-based hydrogels
Leah Pandiscia, PhD
October 11, 2018
Chiral self-assembly has drawn increasing interest in supramolecular chemistry. Here, we have designed amphiphilic l-Pro–l-Glu and l-Pro–d-Glu dipeptides and investigated their chiral… Continue reading Self-Assembly of Amphiphilic Dipeptide with Homo- and Heterochiral Centers and Their Application in Asymmetric Aldol Reaction
Leah Pandiscia, PhD
October 11, 2018
Leah Pandiscia, PhD
October 11, 2018
Herein, we report the helical inversion of supramolecular polymeric complexes of Co2+containing a peptide‐based ligand comprising one alanine and three… Continue reading Helical Inversion of Peptide‐based Supramolecular Co2+Complexes
Leah Pandiscia, PhD
October 11, 2018
The authors describe a molecular beacon-based fluorescent probe for the determination of the cancer drug bleomycin (BLM). The probe was… Continue reading Molecular beacon-templated silver nanoclusters as a fluorescent probe for determination of bleomycin via DNA scission
Leah Pandiscia, PhD
October 11, 2018
New recyclable chiral salen complexes Cr(III) 1–7 were synthesized from various macrocyclic chiral ligands having multistereogenic chiral centers which work synergistically to give… Continue reading Development of recyclable chiral macrocyclic metal complexes for asymmetric aminolysis of epoxides: application for the synthesis of an enantiopure oxazolidine ring
Leah Pandiscia, PhD
October 11, 2018
RNA, which plays an important role in the transcription and translation of genetic processes, has novel functional material abilities, such… Continue reading Preparation of water‐insoluble and biochemically stable RNA hybrid material
Leah Pandiscia, PhD
October 11, 2018
The effect of microwave and ultrasonic processing on the secondary structure of egg white protein was evaluated using Fourier-transform infrared… Continue reading Effects of Ultrasonic and Microwave Processing on Avidin Assay and Secondary Structures of Egg White Protein
Leah Pandiscia, PhD
October 11, 2018
Leah Pandiscia, PhD
October 11, 2018
The worldwide emergence of antibiotic resistance poses a serious threat to human health. A molecular understanding of resistance strategies employed… Continue reading Molecular insights into antibiotic resistance – how a binding protein traps albicidin
Leah Pandiscia, PhD
October 11, 2018
Heparin is the most widely studied glycosaminoglycan. It plays an important role in regulating several normal physiological and pathological processes,… Continue reading Facile synthesis of near-infrared emitting dBSA-templated Cu nanoclusters for sensitive detection of heparin
Leah Pandiscia, PhD
October 11, 2018
Leah Pandiscia, PhD
October 11, 2018
Single-molecule techniques allow unique insights into biological systems as they provide unrivaled access to structural dynamics and conformational heterogeneity. One… Continue reading The Protein Microenvironment Governs the Suitability of Labeling Sites for Single-Molecule Spectroscopy of RNP Complexes
Leah Pandiscia, PhD
October 11, 2018
The development of Ru(II) complexes as luminescent probes has attracted increasing attention in recent decades. In this study, the nanosized… Continue reading Preparation of Ru(II)@oligonucleotide nanosized polymers as potential tumor-imaging luminescent probes
Leah Pandiscia, PhD
October 11, 2018
As a promising agent for biomedical application, collagen has been used as a nanofiber to architecturally mimic its fibrillar structure… Continue reading Collagen/Polyethylene Oxide Nanofibrous Membranes with Improved Hemostasis and Cytocompatibility for Wound Dressing
Leah Pandiscia, PhD
October 11, 2018
Three new dihydrobenzofuran neolignans, myticaganal A–C (1–3), along with five known compounds (4–8), were isolated from the seeds of Myristica fragrans.… Continue reading New neolignans from the seeds of Myristica fragransand their cytotoxic activities
Leah Pandiscia, PhD
October 11, 2018
Protein misfolding and fibrillation are the fundamental traits in degenerative diseases like Alzheimer’s, Parkinsonism, and diabetes mellitus. Bioactives such as… Continue reading Andrographolide inhibits human serum albumin fibril formations through site-specific molecular interactions
Leah Pandiscia, PhD
October 11, 2018