Found 9617 Results / Page 283 of 481
2018 / Scientific Reports
Alzheimer’s disease (AD) is the most prevalent neurodegenerative disease in the elderly. Zinc (Zn) ion interacts with the pathogenic hallmark,… Continue reading Zinc ion rapidly induces toxic, off-pathway amyloid-β oligomers distinct from amyloid-β derived diffusible ligands in Alzheimer’s disease
2018 / The Journal of Physical Chemistry B
Synthesis and self-assembly of bioconjugates composed of proteins and synthetic molecules have been widely studied because of the potential applications… Continue reading Coassembly of Lysozyme and Amphiphilic Biomolecules Driven by Unimer–Aggregate Equilibrium
2018 / Journal of Materials Chemistry B
This report describes the synthesis and structure of core–shell protein clusters comprising haemoglobin (Hb) at the centre and recombinant feline… Continue reading Core–shell protein clusters comprising haemoglobin and recombinant feline serum albumin as an artificial O2 carrier for cats
2018 / Journal of Materials Chemistry B
Developing bioactive hydrogels with the potential to guide the differentiation behavior of stem cells has become increasingly important in the… Continue reading Bioactive silk hydrogels with tunable mechanical properties
2018 / Journal of Materials Chemistry B
In this study, a peptide-based artificial hydrolase with photo-switchable activity was fabricated through introducing a catalytic histidine residue and a… Continue reading A supramolecular approach to construct a hydrolase mimic with photo-switchable catalytic activity
2018 / Food & Function
Fluorescent nanoparticles (FNPs) produced from roast meat have drawn widespread attention due to their potential hazards to human health. In… Continue reading Ultrasmall fluorescent nanoparticles derived from roast duck: their physicochemical characteristics and interaction with human serum albumin
2018 / Nucleic Acids Research
Left-handed Z-DNA is an extraordinary conformation of DNA, which can form by special sequences under specific biological, chemical or physical conditions.… Continue reading Unveiling the pathway to Z-DNA in the protein-induced B–Z transition
2018 / Analytical and Bioanalytical Chemistry
We report on the influence of pH and monovalent/divalent cations on the catalytic current response, internal electron transfer (IET), and… Continue reading The influence of pH and divalent/monovalent cations on the internal electron transfer (IET), enzymatic activity, and structure of fructose dehydrogenase
2018 / The Journal of Organic Chemistry
Determination of a thermal E/Z isomerization barrier of first generation molecular motors is reported. Stable (E)-1a directly converts to stable (Z)-1c without photochemical E/Z isomerization. The… Continue reading Thermal E/Z Isomerization in First Generation Molecular Motors
2018 / Journal of Molecular Recognition
The β‐subunit of the human eukaryotic elongation factor 1 complex (heEF1β) plays a central role in the elongation step in… Continue reading An update on the biophysical character of the human eukaryotic elongation factor 1 beta: Perspectives from interaction with elongation factor 1 gamma
2018 / Chirality
This study demonstrates the supramolecular chirality control of a conjugated polymer via solvent polarity. We designed and synthesized a chiral… Continue reading Solvent polarity effects on supramolecular chirality of a polyfluorene‐thiophene copolymer
2018 / Journal of Molecular LIquids
The novel β-enamino thiosemicarbazide derivatives (Z)-2-(3-(phenethylamino)-but-2-enoyl)-hydrazine carbothioamide (ETS1) and (Z)-N-methyl-2-(3-(phenethylamino)-but-2-enoyl)-hydrazine carbothioamide (ETS2) as well as their β-enamino ester precursor (Z)-ethyl-3-(phenethylamino)-but-2-enoate… Continue reading Synthesis, tyrosinase inhibition and transportation behavior of novel β- enamino thiosemicarbazide derivatives by human serum albumin
2018 / Nature Communications
Recently, ligand–metal coordination, stimuli-responsive covalent bonds, and mechanically interlinked molecular constructs have been used to create systems with a large… Continue reading Control over multiple molecular states with directional changes driven by molecular recognition
2018 / Physical Chemistry Chemical Physics
Interaction of ionic liquid (IL) with protein is now becoming important in stabilizing the protein due to the selective cation-anion… Continue reading Selective binding and dynamics of imidazole alkyl sulfate ionic liquids with human serum albumin and collagen −A detailed NMR investigation
2018 / International Wound Journal
A peptide might be an exciting biomaterial or template for the development of novel wound-healing agents. In this report, it… Continue reading Functional characterisation of bioactive peptide derived from terrestrial snail Cryptozona bistrialis and its wound-healing property in normal and diabetic-induced Wistar albino rats
2018 / Scientific Reports
Cytolysin A (ClyA) is a water-soluble alpha pore-forming toxin that assembles to form an oligomeric pore on host cell membranes.… Continue reading Disruption of the open conductance in the β-tongue mutants of Cytolysin A
2018 / Protein Science
The repetitive self-assembled structure of amyloid can serve as inspiration to design functional materials. Herein, we describe the design of… Continue reading Dynamic Protein Folding at the Surface of Stimuli-Responsive Peptide Fibrils
2018 / Proteins: Structure, Function, and Bioinformatics
Non-natural protein sequences with native-like structures and functions can be constructed successfully using consensus design. This design strategy is relatively… Continue reading Phylogenetic Spread of Sequence Data Affects Fitness of SOD1 Consensus Enzymes: Insights from Sequence Statistics and Structural Analyses
2018 / Scientific Reports
Synthetic peptides derived from ethylene-insensitive protein 2 (EIN2), a central regulator of ethylene signalling, were recently shown to delay fruit… Continue reading Recognition motif and mechanism of ripening inhibitory peptides in plant hormone receptor ETR1
2018 / ChemBioChem
Since the discovery of the biological relevance of rare earth elements (REE) for numerous different bacteria, the questions of the… Continue reading Similar but not the same: First Kinetic and Structural Analyses of a Methanol Dehydrogenase Containing a Europium Ion in the Active Site
