Found 9617 Results / Page 306 of 481

Structural switch from a multistranded G-quadruplex to single strands as a consequence of point mutation in the promoter of the human GRIN1 gene

2017 / Molecular BioSystems

A huge number of G-rich sequences forming quadruplexes are found in the human genome, especially in telomeric regions, UTRs, and… Continue reading Structural switch from a multistranded G-quadruplex to single strands as a consequence of point mutation in the promoter of the human GRIN1 gene

Leah Pandiscia, PhD

Probing the formation of supramolecular assemblies of amphiphilic N-methyl glycine and N,N dimethyl β-alanine derivatives

2017 / New Journal of Chemistry

Supramolecular assemblies were prepared using new amphiphilic dervivatives of N-methyl gylcine and N,N dimethyl-β-alanine. Both N-methylated amino acids were conjugated with 1,4 diamino butane… Continue reading Probing the formation of supramolecular assemblies of amphiphilic N-methyl glycine and N,N dimethyl β-alanine derivatives

Leah Pandiscia, PhD

A cobalt–nitrosyl complex with a hindered hydrotris(pyrazolyl)borate coligand: detailed electronic structure, and reactivity towards dioxygen

2017 / Dalton Transactions

The cobalt–nitrosyl complex [Co(NO)(L3)] is supported by a highly hindered tridentate nitrogen ligand, hydrotris(3-tertiary butyl-5-isopropyl-1-pyrazolyl)borate (denoted as L3−), and shows a linear… Continue reading A cobalt–nitrosyl complex with a hindered hydrotris(pyrazolyl)borate coligand: detailed electronic structure, and reactivity towards dioxygen

Leah Pandiscia, PhD

Norsampsone E, an unprecedented decarbonyl polycyclic polyprenylated acylphloroglucinol with a homoadamantyl core from Hypericum sampsonii†

2017 / RSC Advances

Norsampsone E (1), an unprecedented decarbonyl polycyclic polyprenylated acylphloroglucinol, together with one new and two known analogues (2–4), was isolated… Continue reading Norsampsone E, an unprecedented decarbonyl polycyclic polyprenylated acylphloroglucinol with a homoadamantyl core from Hypericum sampsonii†

Leah Pandiscia, PhD

A novel platinum(II) anticancer complex of danysl bis(2-benzothiazolylmethyl)amine with dimethyl sulfoxide as a leaving group: synthesis, cytotoxicity, interaction with DNA and human serum albumin

2017 / New Journal of Chemistry

A novel mononuclear platinum(II) complex, [PtL(DMSO)Cl]Cl (1, here L = danysl bis(2-benzothiazolylmethyl)amine), has been synthesized and characterized by ESI-MS, IR spectrum, 1H NMR, 13C… Continue reading A novel platinum(II) anticancer complex of danysl bis(2-benzothiazolylmethyl)amine with dimethyl sulfoxide as a leaving group: synthesis, cytotoxicity, interaction with DNA and human serum albumin

Leah Pandiscia, PhD

Probing the binding mechanism of polybrominated diphenyl ethers with transthyretin by multi-spectroscopic and molecular dynamics simulations

2017 / Analytical Methods

The physical and chemical properties of polybrominated diphenyl ethers (PBDEs) are important for modeling their transport. The primary objective of… Continue reading Probing the binding mechanism of polybrominated diphenyl ethers with transthyretin by multi-spectroscopic and molecular dynamics simulations

Leah Pandiscia, PhD

Influence of substituents on DNA and protein binding of cyclometalated Ir(III) complexes and anticancer activity

2017 / Dalton Transactions

Synthesis of terpyridyl based ligands 3-([2,2′:6′,2′′-terpyridin]-4′-yl)-7-methoxy-2-(methylthio)-quinolone, (L1); 3-([2,2′:6′,2′′-terpyridin]-4′-yl)-6-methoxyquinolin-2(1H)-one, (L2); 3-([2,2′-:6′,2′′-terpyridin]-4′-yl)-6-methylquinolin-2(1H)-one (L3) and cyclometalated iridium(III) complexes [[Ir(ppy)2L1]+PF6− (1), [Ir(ppy)2L2]+PF6− (2), [Ir(ppy)2L3]+PF6− (3) (2-phenylpyridine =… Continue reading Influence of substituents on DNA and protein binding of cyclometalated Ir(III) complexes and anticancer activity

Leah Pandiscia, PhD
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