KnowledgeBase Articles Archive

Enhanced anti-cancer efficacy to cancer cells by a novel monofunctional mononuclear platinum(II) complex containing a mixed S,N,S-donor ligand

2017 / New Journal of Chemistry

A novel mononuclear platinum(II) complex, [PtLCl]Cl (1, where L = N-(4-(benzo[d]oxazol-2-yl)phenyl)-2-(bis(2-ethylthioethyl)amino)acetamide), was synthesized containing an S,N,S-donor monochloroplatinum(II) moiety tethered to a planar 2-(4-aminophenyl)benzoxazole unit… Continue reading Enhanced anti-cancer efficacy to cancer cells by a novel monofunctional mononuclear platinum(II) complex containing a mixed S,N,S-donor ligand

The first identified cathelicidin from tree frogs possesses anti-inflammatory and partial LPS neutralization activities

2017 / Amino Acids

As of February 2017, approximately 7639 amphibian species have been described in the AmphibiaWeb database. However, only 20 cathelicidin-like antimicrobial… Continue reading The first identified cathelicidin from tree frogs possesses anti-inflammatory and partial LPS neutralization activities

Aggregation-induced emission enhancement and aggregation-induced circular dichroism of chiral pentaphenylpyrrole derivatives and their helical self-assembly

2017 / New Journal of Chemistry

Herein, a pair of enantiomers, (S)-PPPtriAm and (R)-PPPtriAm, with three chiral substituents and their raceme rac-PPPtriAm derived from conjugated luminogen pentaphenylpyrrole… Continue reading Aggregation-induced emission enhancement and aggregation-induced circular dichroism of chiral pentaphenylpyrrole derivatives and their helical self-assembly

A collagen telopeptide binding peptide shows potential in aiding collagen bundle formation and fibril orientation

2017 / Biomaterials Science

Type I collagen, the main component of the extracellular matrix (ECM), assembles into bundles, which are then arranged in an… Continue reading A collagen telopeptide binding peptide shows potential in aiding collagen bundle formation and fibril orientation

High-Yield Site-Specific Conjugation of Fibroblast Growth Factor 1 with Monomethylauristatin E via Cysteine Flanked by Basic Residues

2017 / Bioconjugate Chemistry

Site-specific conjugation is a leading trend in the development of protein conjugates, including antibody–drug conjugates (ADCs), suitable for targeted cancer… Continue reading High-Yield Site-Specific Conjugation of Fibroblast Growth Factor 1 with Monomethylauristatin E via Cysteine Flanked by Basic Residues

PH-Dependent Enantioselectivity of D-amino Acid Oxidase in Aqueous Solution

2017 / Scientific Reports

D-amino acid oxidases (DAAO) are stereospecific enzymes which are generally almost inactive towards L-enantiomer in neutral solution when L-, D-amino… Continue reading PH-Dependent Enantioselectivity of D-amino Acid Oxidase in Aqueous Solution

Formation of Annular Protofibrillar Assembly by Cysteine Tripeptide: Unraveling the Interactions with NMR, FTIR, and Molecular Dynamics

2017 / The Journal of Physical Chemistry B

Both hydrogen-bonding and hydrophobic interactions play a significant role in molecular assembly, including self-assembly of proteins and peptides. In this… Continue reading Formation of Annular Protofibrillar Assembly by Cysteine Tripeptide: Unraveling the Interactions with NMR, FTIR, and Molecular Dynamics

Spectroscopic studies on the comparative refolding of guanidinium hydrochloride denatured hen egg-white lysozyme and Rhizopus niveus lipase assisted by cationic single-chain/gemini surfactants via artificial chaperone protocol

2017 / RSC Advances

Referred to as second generation surfactants, the gemini surfactants have shown promise in various potential areas of surfactant application. Here… Continue reading Spectroscopic studies on the comparative refolding of guanidinium hydrochloride denatured hen egg-white lysozyme and Rhizopus niveus lipase assisted by cationic single-chain/gemini surfactants via artificial chaperone protocol

Biochemical characterization of LR769, a new recombinant factor VIIa bypassing agent produced in the milk of transgenic rabbits

2017 / Haemophilia

The bypassing agent factor VII (FVIIa) is a first-line therapy for the treatment of acute bleeding episodes in patients with… Continue reading Biochemical characterization of LR769, a new recombinant factor VIIa bypassing agent produced in the milk of transgenic rabbits

Efficient Upconversion by Highly Water-Soluble Cationic Sensitizer and Emitter in Aqueous Solutions with DNA

2017 / ACS Biomaterials Science & Engineering

Highly water-soluble cationic palladium porphyrin as a sensitizer and 9,10-bis(4-trimethylammoniumphenyl)anthracene as an emitter were newly synthesized. They were shown to… Continue reading Efficient Upconversion by Highly Water-Soluble Cationic Sensitizer and Emitter in Aqueous Solutions with DNA

The Inclusion of Chitosan in Poly-ε-caprolactone Nanoparticles: Impact on the Delivery System Characteristics and on the Adsorbed Ovalbumin Secondary Structure

2017 / AAPS PharmSciTech

This report extensively explores the benefits of including chitosan into poly-ε-caprolactone (PCL) nanoparticles (NPs) to obtain an improved protein/antigen delivery… Continue reading The Inclusion of Chitosan in Poly-ε-caprolactone Nanoparticles: Impact on the Delivery System Characteristics and on the Adsorbed Ovalbumin Secondary Structure

Structural Basis for Mitotic Centrosome Assembly in Flies

2017 / Cell

In flies, Centrosomin (Cnn) forms a phosphorylation-dependent scaffold that recruits proteins to the mitotic centrosome, but how Cnn assembles into… Continue reading Structural Basis for Mitotic Centrosome Assembly in Flies

Zn(II) and Ni(II) complexes with poly-histidyl peptides derived from a snake venom

2017 / Inorganica Chimica Acta

The snake venoms are complex mixtures containing many bioactive peptides and proteins; some of them are aimed to protect the… Continue reading Zn(II) and Ni(II) complexes with poly-histidyl peptides derived from a snake venom

Gallic acid induced dose dependent inhibition of lysozyme fibrillation

2017 / International Journal of Biological Macromolecules

Amyloidosis is primarily characterized by the deposition of misfolded protein aggregates. Although the natural polyphenols have long been known as… Continue reading Gallic acid induced dose dependent inhibition of lysozyme fibrillation

Probing Tertiary Structure of Proteins Using Single Trp Mutations with Circular Dichroism at Low Temperature

2014 / The Journal of Physical Chemistry B

Trp is the most spectroscopically informative aromatic amino acid of proteins. However, the near-UV circular dichroism (CD) spectrum of Trp… Continue reading Probing Tertiary Structure of Proteins Using Single Trp Mutations with Circular Dichroism at Low Temperature

Physicochemical, conformational and functional properties of silver carp myosin glycated with konjac oligo-glucomannan: Implications for structure-function relationships

2017 / Food Hydrocolloids

Silver carp myosin (Ms) was glycated with konjac oligo-glucomannan (KOG) under dry reaction conditions. The physicochemical properties (amino acid composition,… Continue reading Physicochemical, conformational and functional properties of silver carp myosin glycated with konjac oligo-glucomannan: Implications for structure-function relationships

Cerium oxide nanoparticles promote HSA fibrillation in vitro

2017 / International Journal of Biological Macromolecules

Physicochemical characterization of CeO2NPs using UV–vis, FTIR and XRD have confirmed the characteristic identity and fluorite phase of their crystalline… Continue reading Cerium oxide nanoparticles promote HSA fibrillation in vitro

Sequential oxic-anoxic bio reactor for the treatment of tannery saline wastewater using halophilic and filamentous bacteria

2017 / Journal of Water Process Engineering

The present investigation was focused on the removal of dissolved organics and suspended solids from tannery saline wastewater [TSWW]Raw, known… Continue reading Sequential oxic-anoxic bio reactor for the treatment of tannery saline wastewater using halophilic and filamentous bacteria

Salt-regulated reversible fibrillation of Mycobacterium tuberculosis isocitrate lyase: Concurrent restoration of structure and activity

2017 / International Journal of Biological Macromolecules

Protein fibrillation is associated with a number of neurodegenerative diseases. Nevertheless, several proteins not related to disease can also form… Continue reading Salt-regulated reversible fibrillation of Mycobacterium tuberculosis isocitrate lyase: Concurrent restoration of structure and activity

High hydrostatic pressure encapsulation of doxorubicin in ferritin nanocages with enhanced efficiency

2017 / Journal of Biotechnology

Human ferritin (HFn) nanocaging is becoming an appealing platform for anticancer drugs delivery. However, protein aggregation always occurs during the… Continue reading High hydrostatic pressure encapsulation of doxorubicin in ferritin nanocages with enhanced efficiency

JASCO

KnowledgeBase Articles

Year

Technique

Industry

Enhanced anti-cancer efficacy to cancer cells by a novel monofunctional mononuclear platinum(II) complex containing a mixed S,N,S-donor ligand

The first identified cathelicidin from tree frogs possesses anti-inflammatory and partial LPS neutralization activities

Aggregation-induced emission enhancement and aggregation-induced circular dichroism of chiral pentaphenylpyrrole derivatives and their helical self-assembly

A collagen telopeptide binding peptide shows potential in aiding collagen bundle formation and fibril orientation

High-Yield Site-Specific Conjugation of Fibroblast Growth Factor 1 with Monomethylauristatin E via Cysteine Flanked by Basic Residues

PH-Dependent Enantioselectivity of D-amino Acid Oxidase in Aqueous Solution

Formation of Annular Protofibrillar Assembly by Cysteine Tripeptide: Unraveling the Interactions with NMR, FTIR, and Molecular Dynamics

Spectroscopic studies on the comparative refolding of guanidinium hydrochloride denatured hen egg-white lysozyme and Rhizopus niveus lipase assisted by cationic single-chain/gemini surfactants via artificial chaperone protocol

Biochemical characterization of LR769, a new recombinant factor VIIa bypassing agent produced in the milk of transgenic rabbits

Efficient Upconversion by Highly Water-Soluble Cationic Sensitizer and Emitter in Aqueous Solutions with DNA

The Inclusion of Chitosan in Poly-ε-caprolactone Nanoparticles: Impact on the Delivery System Characteristics and on the Adsorbed Ovalbumin Secondary Structure

Structural Basis for Mitotic Centrosome Assembly in Flies

Zn(II) and Ni(II) complexes with poly-histidyl peptides derived from a snake venom

Gallic acid induced dose dependent inhibition of lysozyme fibrillation

Probing Tertiary Structure of Proteins Using Single Trp Mutations with Circular Dichroism at Low Temperature

Physicochemical, conformational and functional properties of silver carp myosin glycated with konjac oligo-glucomannan: Implications for structure-function relationships

Cerium oxide nanoparticles promote HSA fibrillation in vitro

Sequential oxic-anoxic bio reactor for the treatment of tannery saline wastewater using halophilic and filamentous bacteria

Salt-regulated reversible fibrillation of Mycobacterium tuberculosis isocitrate lyase: Concurrent restoration of structure and activity

High hydrostatic pressure encapsulation of doxorubicin in ferritin nanocages with enhanced efficiency

JASCO provides services and support to a diverse range of industries throughout the world.