Found 9617 Results / Page 350 of 481
2017 / PLoS ONE
The metastasis suppressor KISS1 is reported to be involved in the progression of several solid neoplasias, making it a promising… Continue reading The metastasis suppressor KISS1 is an intrinsically disordered protein slightly more extended than a random coil
2017 / Food and Chemical Toxicology
Chinese chive (jiu cai) is a popular vegetable in China and has a unique flavour and aroma. The molecular basis… Continue reading Isolation and identification of new chemical constituents from Chinese chive (Allium tuberosum) and toxicological evaluation of raw and cooked Chinese chive
2017 / Journal of Pharmaceutical and Biomedical Analysis
Albendazole (ABZ) is a sulfanyl-benzimidazole anthelmintic drug used worldwide in the treatment and prevention of parasitic diseases in animals and… Continue reading The sodium salt of the enantiomers of ricobendazole: Preparation, solubility and chiroptical properties
2017 / Macromolecular Chemistry and Physics
Hydrogel as a carrier for drug delivery system has been developed, but it is hard to change the load and… Continue reading Coassembly Modulated pH-Responsive Hydrogel for Dye Absorption and Release
2017 / Dyes and Pigments
Novel chiral pyrene-binaphthalene compounds, (R)-/(S)-(13Z,21bZ)-dinaphtho[2,1-e:1′,2′-g]pyreno[4,5-b][1,4]diazocine (1) and (R)-/(S)-(3bZ,5Z,7Z,9Z,12bZ,14Z,16Z,18Z)-bis(dinaphtho[2,1-e:1′,2′-g])pyreno[4,5-b:9,10-b′]bis([1,4]diazocine) (2), were synthesized and characterized by a series of spectroscopic methods including… Continue reading Novel chiral binaphthalene-linked pyrenes. Synthesis, structure, and spectroscopy
2017 / RSC Advances
Extraction and separation of proteins is important for their interesting applications as continuous enzymatic reaction and/or product separation systems. In… Continue reading Homogeneous capture and heterogeneous separation of proteins by PEG-functionalized ionic liquid–water systems
2017 / The Journal of Chemical Thermodynamics
Protein-drug interaction offer information of the structural features that determine the therapeutic effectiveness of drug and have become an attractive… Continue reading Thermodynamics and binding mechanism of polyphenon-60 with human lysozyme elucidated by calorimetric and spectroscopic techniques
2017 / Nature Structural & Molecular Biology
Deposition of amyloid- plaques is increased in the brains of HIV-infected individuals, and the HIV transactivator of transcription (Tat) protein… Continue reading HIV Tat protein and amyloid-β peptide form multifibrillar structures that cause neurotoxicity
2017 / Carbohydrate Polymers
Hydroxypropyl methylcellulose (HPMC) and xyloglucan (XG) crosslinked with citric acid over a range of HPMC/XG weight ratios formed sustainable blend… Continue reading Sustainable hydroxypropyl methylcellulose/xyloglucan/gentamicin films with antimicrobial properties
2017 / Colloids and Surfaces B: Biointerfaces
To improve the interfacial properties, a phosphorylation modification of OVA was performed through dry-heating at three different pH values (5.0,… Continue reading Enhanced ovalbumin stability at oil-water interface by phosphorylation and identification of phosphorylation site using MALDI-TOF mass spectrometry
2017 / Biochimie
G-quadruplexes (G4s) are high-order secondary structures that modulate several key cell processes such as telomere function, gene expression and DNA… Continue reading Study of the interaction between indole-based compounds and biologically relevant G-quadruplexes
2017 / Protein Science
ATG14 binding to BECN/Beclin homologs is essential for autophagy, a critical catabolic homeostasis pathway. Here we show that the α-helical,… Continue reading BECN2 interacts with ATG14 through a metastable coiled-coil to mediate autophagy
2017 / Biochemistry and Biophysics Reports
Sortase A catalyzed ligation of ultra-short peptides leads to inter/intra-molecular transpeptidation to form either linear or cyclic oligomers dependent upon… Continue reading Peptide oligomers from ultra-short peptides using sortase
2017 / Molecular Cell
Protein function originates from a cooperation of structural rigidity, dynamics at different timescales, and allostery. However, how these three pillars… Continue reading Conformational Rigidity and Protein Dynamics at Distinct Timescales Regulate PTP1B Activity and Allostery
2017 / Acta Biomaterialia
Nanoparticles (NPs) can have profound effects on cell biology. However, the potential adverse effects of gold nanoparticles (AuNPs) with different… Continue reading Cytotoxicity of gold nanoparticles with different structures and surface-anchored chiral polymers
2017 / Journal of Peptide Science
Coiled coils, consisting of at least two α-helices, have important roles in the regulation of transcription, cell differentiation, and cell… Continue reading Heterochiral Jun and Fos bZIP peptides form a coiled-coil heterodimer that is competent for DNA binding
2017 / Phytochemistry
Seven anthraquinones were isolated from aerial parts of Heterophyllaea lycioides (Rusby) Sandwith (Rubiaceae), including three derivatives that have not been described before:… Continue reading Photosensitizing anthraquinones from Heterophyllaea lycioides (Rubiaceae)
2017 / Scientific Reports
Diaminopimelate epimerase (DapF) is one of the crucial enzymes involved in L-lysine biosynthesis, where it converts L,L-diaminopimelate (L,L-DAP) into D,L-DAP. DapF is also… Continue reading Structural basis for redox sensitivity in Corynebacterium glutamicumdiaminopimelate epimerase: an enzyme involved in L-lysine biosynthesis
2017 / Chemistry A European Journal
Achiral stilbene polycatenars forming smectic, columnar or cubic phase depending on the terminal chains length, were studied. The cubic Im3m… Continue reading Optically active cubic liquid crystalline phase made of achiral polycatenar stilbene derivatives
2017 / New Journal of Chemistry
We are currently investigating self-assembled nanostructures from short oligomers of β-amino acids and their subsequent use as drug delivery systems.… Continue reading Self-assembled amphiphilic mixed α/β-tetrapeptoid nanostructures as promising drug delivery vehicles
