Found 9617 Results / Page 358 of 481
2017 / International Journal of Biological Macromolecules
Studying the mode of interaction between small molecules and DNA has received much attention in recent years, as many drugs… Continue reading Interaction of capsaicin with calf thymus DNA: A multi-spectroscopic and molecular modelling study
2017 / Tetrahedron
The unusual (R) configuration previously assigned (with seemingly undoubted evidence) to purpuroin A and nakirodin A was disproved by synthesis.… Continue reading Synthesis of purpuroine A, nakirodin A and MDN-0104: The hidden puzzles and risk of error in their configurational assignments
2017 / International Journal of Mass Spectrometry
In this research, ESI mass spectrometry was used to probe the formation of G-quadruplexes from three G-rich sequences (S1–S3) in… Continue reading Exploration of a multi-target ligand, dehydroevodiamine, for the recognition of three G-quadruplexes in c-Myb proto-oncogene by ESI–MS
2017 / Biochimica et Biophysica Acta (BBA) - General Subjects
G-quadruplexes (G4s) have become important drug targets to regulate gene expression and telomere maintenance. Many studies on G4 ligand binding… Continue reading What stoichiometries determined by mass spectrometry reveal about the ligand binding mode to G-quadruplex nucleic acids ☆
2017 / Frontiers of Chemical Science and Engineering
The application of gene delivery materials has been mainly focused on mammalian cells while rarely extended to plant engineering. Cationic… Continue reading Gene delivery into isolated Arabidopsis thaliana protoplasts and intact leaves using cationic, α-helical polypeptide
2017 / European Journal of Organic Chemistry
Self-assembly using imine condensation chemistry in combination with metal coordination is becoming one of the leading strategies for the preparation… Continue reading Second Generation tris(2-pyridylmethyl)amine Zinc Complexes as Probes for Enantiomeric Excess Determination of Amino Acids
2017 / Peptide Science
Hydrophobicity has proven to be an extremely useful parameter in small molecule drug discovery programmes given that it can be… Continue reading Log D versus HPLC derived hydrophobicity: The development of predictive tools to aid in the rational design of bioactive peptoids
2017 / Polymer Chemistry
This paper reports a new ratiometric probe for the detection of adenosine 5′-triphosphate (ATP) that is based on the binding-induced… Continue reading A new FRET-based ratiometric probe for fluorescence and colorimetric analyses of adenosine 5′-triphosphate
2017 / Scientific Reports
Nucleoplasmins are a nuclear chaperone family defined by the presence of a highly conserved N-terminal core domain. X-ray crystallographic studies… Continue reading Nucleoplasmin-like domain of FKBP39 from Drosophila melanogaster forms a tetramer with partly disordered tentacle-like C-terminal segments
2017 / ACS Sustainable Chemistry & Engineering
Packaging as well as preservation of DNA in nonaqueous media at ambient conditions for long durations is an important research… Continue reading Very High Concentration Solubility and Long-Term Stability of DNA in an Ammonium-Based Ionic Liquid: A Suitable Medium for Nucleic Acid Packaging and Preservation
2017 / Biochemistry
Light chain (AL) amyloidosis is a lethal disease characterized by the deposition of the immunoglobulin light chain into amyloid fibrils,… Continue reading Differences in Protein Concentration Dependence for Nucleation and Elongation in Light Chain Amyloid Formation
2017 / Proteins: Structure, Function and Bioinformatics
Porins form trimers in the outer membrane and help transport nutrients and waste products across the bacterial cell membrane. Porin… Continue reading Characterization of Salmonella typhi OmpC and OmpF porins engineered with HIV-gp41 epitope on the surface loops
2017 / Journal of Materials Chemistry C
We report a new optical sensing approach based on the chiral recognition of optically active CoFe2O4 magnetic nanoparticles by CdSe/CdS… Continue reading Chiral recognition of optically active CoFe2O4 magnetic nanoparticles by CdSe/CdS quantum dots stabilised with chiral ligands
2017 / Scientia Pharmaceutica
This paper reports the in vitro characterization of the interaction between the phosphate groups of DNA and the protonated species… Continue reading Interaction between DNA and Drugs Having Protonable Basic Groups: Characterization through Affinity Constants, Drug Release Kinetics, and Conformational Changes
2017 / Analytical and Bioanalytical Chemistry
G-Quadruplex (G4) structures of a human telomeric 24-mer (5′-TTAGGGTTAGGGTTAGGGTTAGGG-3′) sequence (Tel24) stabilized by sodium and potassium ions have been assessed… Continue reading Assessment of human telomeric G-quadruplex structures using surface-enhanced Raman spectroscopy
2017 / Langmuir
Structural control of the self-assembled lipid membrane is an important and interesting challenge, both for revealing the mechanisms behind biological… Continue reading Reversible Vesicle-to-Disk Transitions of Liposomes Induced by Self-Assembly of Water-Soluble Porphyrins
2017 / Analytical Methods
A facile, highly selective biosensor was used for ATP quantitative analysis. Here we introduced two hairpins as matrix. While Exo… Continue reading Free-Labelled Fluorescent Method for ATP Detection Assisted by T4 DNA Ligase
2017 / Food and Bioproducts Processing
In the food industry, biocatalysts provide ecofriendly procedures to accomplish biochemical reactions with high specificity in moderate conditions. In this… Continue reading Production of the Renewable Extremophile Lipase; Valuable Biocatalyst with Potential Usage in Food Industry
2016 / RSC Advances
Lycium chinense Mill. is a deciduous shrub in the Solanaceae family that is known for its fruits (Lycii fructus) and root… Continue reading Nine new compounds from the root bark of Lycium chinense and their α-glucosidase inhibitory activity
2017 / JACS
Improving bioelectrocatalytic current response of redox enzymes on electrodes has been a focus in the development of enzymatic biosensors and… Continue reading Role of Organic Solvents in Immobilizing Laccase on Single-Walled Carbon Nanotubes for Improved Current Response in Direct Bioelectrocatalysis
