Found 9617 Results / Page 380 of 481
2016 / International Journal of Biological Macromolecules
Guanylate kinase is one of the key enzymes in nucleotide biosynthesis. The study highlights the structural and functional properties of Brugia… Continue reading Investigating the folding pathway and substrate induced conformational changes in B. malayi Guanylate kinase
2016 / Journal of Molecular Liquids
Sodium dodecyl sulfate (SDS) and cetyl trimethylammonium bromide (CTAB) are common ionic surfactants. Former researches have investigated the interactions between… Continue reading The interaction mechanism between anionic or cationic surfactant with HSA by using spectroscopy, calorimetry and molecular docking methods
2016 / Journal of Photochemistry and Photobiology B: Biology
Interaction of proflavine with hemoglobin (Hgb) was studied employing spectroscopy, calorimetry, and atomic force microscopy. The equilibrium constant was found… Continue reading A biophysical investigation on the binding of proflavine with human hemoglobin: Insights from spectroscopy, thermodynamics and AFM studies
2016 / Biochemistry and Biophysics Reports
In prokaryotic cells, genomic DNA forms an aggregated structure with various nucleoid-associated proteins (NAPs). The functions of genomic DNA are… Continue reading A specific single-stranded DNA induces a distinct conformational change in the nucleoid-associated protein HU
2016 / European Journal of Medicinal Chemistry
Hand, foot and mouth disease (HFMD) is a serious, highly contagious disease. HFMD caused by Enterovirus 71 (EV71), results in… Continue reading Identification and biochemical characterization of DC07090 as a novel potent small molecule inhibitor against human enterovirus 71 3C protease by structure-based virtual screening
2016 / Journal of Photochemistry and Photobiology B: Biology
Novel bio-relevant monometallic Schiff base complexes of the type, [Cu(L1)2] (1), [Zn(L1)2]·2H2O (2), [Cu(L2)2]·2H2O (3) and [Zn(L2)2]·H2O (4) [L1double bond;… Continue reading Molecular hybridization approach of bio-potent CuII/ZnII complexes derived from N, O donor bidentate imine scaffolds: Synthesis, spectral, human serum albumin binding, antioxidant and antibacterial studies
2016 / Tetrahedron
Cyclocondensation of salicylaldehydes with alkyl acetoacetates and 2-aminobenzothiazoles or 2-amino-thiadiazole/thiazoles under L-proline catalysis gives 4-hetarylamino substituted chromanecarboxylate derivatives. The mechanism… Continue reading Three-component reaction and organocatalysis in one: synthesis of densely substituted 4-aminochromanes
2016 / Phytochemistry
Five new xanthones, named coxanthones A–E (1–5), together with 21 known secondary metabolites (6–26) that include seven xanthones, five flavonoids,… Continue reading Biologically active xanthones from Codonopsis ovata
2016 / Journal of Chromatography A
The chirality of herbicides has been the focus of research. However, there is little information on the enantioseparation of amide… Continue reading Enantioseparation of four amide herbicide stereoisomers using high-performance liquid chromatography
2016 / Chemistry A European Journal
A novel amphiphilic dendron (AZOC8GAc) with three L-glutamic acid units and an azobenzene moiety covalently linked by an alkyl spacer… Continue reading Supra-dendron gelator based on Azobenzene-cyclodextrin Host-Guest interaction: Photoswitched Optical and Chiroptical reversibility
2016 / Molecules
In the present study, 3-(fluorobenzylideneamino)-6-chloro-1-(3,3-dimethylbutanoyl)-phenyl-2,3-dihydroquinazolin-4(1H)-one (FDQL) derivatives have been designed and synthesized to study the interaction between fluorine substituted dihydroquinazoline… Continue reading Comparative Studies of Interactions between Fluorodihydroquinazolin Derivatives and Human Serum Albumin with Fluorescence Spectroscopy
2016 / Biomaterials Science & Engineering
There are many natural examples of smart structures that are able to change conformations and functionalities responding to the external… Continue reading Protein Nanogels with Temperature-Induced Reversible Structures and Redox Responsiveness
2016 / RSC Advances
Misfolded protein molecules tend to self-assemble into highly-ordered aggregates, the so-called amyloid fibrils whose presence in vivo is often symptomatic… Continue reading Molecules of Congo Red caught hopping between insulin fibrils: A chiroptical probe of the dye-amyloid binding dynamics
2016 / Drug Design, Development and Therapy
Bioactive mediators, cytokines, and chemokines have an important role in regulating and optimizing the synergistic action of materials, cells, and… Continue reading Controlled release of TGF-beta 1 from RADA self-assembling peptide hydrogel scaffolds
2016 / Journal of Biological Inorganic Chemistry
RNA G-quadruplexes, as their well-studied DNA analogs, require the presence of cations to fold and remain stable. This is the… Continue reading Distinct differences in metal ion specificity of RNA and DNA G-quadruplexes
2016 / Journal of Photochemistry and Photobiology B: Biology
Interaction of CT DNA with Rhodamine 6G (R6G) has been studied using molecular docking, electrochemical, spectroscopic and thermodynamic methods. From… Continue reading Biochemical activity of a fluorescent dye rhodamine 6G: Molecular modeling, electrochemical, spectroscopic and thermodynamic studies
2015 / Journal of Fluorescence
Novel conjugate 2,6-Diisopropylphenol-Oleic acid (2,6P-OLA) has shown potent anticancer activity on various cancer cell lines (Khan et al. Lipids 47:973–986, 2012).… Continue reading Biophysical Interactions of Novel Oleic Acid Conjugate and its Anticancer Potential in HeLa Cells
2016 / Scientific Reports
The opportunistic pathogen Staphylococcus aureus is recognized as one of the most frequent causes of biofilm-associated infections. The recently discovered phenol soluble… Continue reading Dissecting the contribution ofStaphylococcus aureus α-phenol-soluble modulins to biofilm amyloid structure
2016 / Applied Surface Science
The Huisgen cycloaddition reaction (“click” chemistry) has been used extensively to functionalize surfaces with macromolecules in a straightforward manner. We… Continue reading One-Pot Reaction for the Preparation of Biofunctionalized Self-Assembled Monolayers on Gold Surfaces
2016 / Applied Materials and Interfaces
Reactive oxygen species (ROS) are a double-edged sword that possesses both beneficial and harmful effects. Although basic research on skin… Continue reading Biofilm Impeding AgNPs Target Skin Carcinoma by Inducing Mitochondrial Membrane Depolarization Mediated through ROS Production
