Found 9617 Results / Page 382 of 481
2016 / European Journal of Pharmaceutical Sciences
Glycoengineering of mAbs has become common practice in attempts to generate the ideal mAb candidate for a wide range of… Continue reading Inhibition of glycosylation on a camelid antibody uniquely affects its FcγRI binding activity
2016 / Biochemical and Biophysical Research Communications
The hallmark feature of Mycobacterium tuberculosis (M.tb) the causative agent of human tuberculosis, is its complex lipid rich cell wall comprised primarily… Continue reading The Mycobacterium tuberculosis desaturase DesA1 (Rv0824c) is a Ca2+ binding protein
2016 / Journal of Molecular Biology
Cell polarity arises from a combination of interactions between biological molecules, such as activation, inhibition, and positive or negative feedback… Continue reading In vitro reconstitution of a membrane switch mechanism for the polarity protein LGL
2016 / Phytochemistry
The intake of Narthecium ossifragum, commonly known as bog asphodel, has been associated with toxic effects observed in sheep for centuries.… Continue reading Toxic aromatic compounds from fruits of Narthecium ossifragum L.
2016 / Archives of Biochemistry and Biophysics
Two structural Ca2+ (proximal and distal) is known to be important for ligninolytic peroxidases. However, few studies toward impact of residues… Continue reading Insight into the impact of two structural calcium ions on the properties of Pleurotus eryngii versatile ligninolytic peroxidase
2016 / Food Hydrocolloids
Gelatin films plasticized with different glycerol contents (0–40%) were cross-linked using transglutaminase (TGase). Unmodified films were prepared as controls. Cross-linking… Continue reading Study of combined effects of glycerol and transglutaminase on properties of gelatin films
2016 / Journal of Food Engineering
In this study, the effect of ball-milling (BM, Mixer Mill MM 400) treatments on the physicochemical properties of soybean protein… Continue reading Ball-milling changed the physicochemical properties of SPI and its cold-set gels
2016 / Scientific Reports
Nascent proteins fold co-translationally because the folding speed and folding pathways are limited by the rate of ribosome biosynthesis in… Continue reading Structural studies of the N-terminal fragments of the WW domain: Insights into co-translational folding of a beta-sheet protein
2016 / RSC Advances
A new and facilely prepared light scattering (LS) and fluorometric dual-mode sensor is developed for lead ion (Pb2+) detection with… Continue reading Dual-modal light scattering and fluorometric detection of lead ion by stimuli-responsive aggregation of BSA-stabilized copper nanoclusters
2016 / Journal of the Royal Society
Water sources pollution by arsenic ions is a serious environmental problem all around the world. Arsenate reductase enzyme (TtArsC) from Thermus… Continue reading Arsenate reductase from Thermus thermophilus conjugated to polyethylene glycol-stabilized gold nanospheres allow trace sensing and speciation of arsenic ions
2016 / ACS Biomaterials Science and Engineering
Engineering protein hydrogels with dynamically tunable mechanical and physical properties is of great interests due to their potential applications in… Continue reading Metal chelation dynamically regulates the mechanical properties of engineered protein hydrogels
2016 / Biochimie
In this work the dimerization process of the minor allelic form of human alanine glyoxylate aminotransferase, a pyridoxal 5′-phosphate enzyme,… Continue reading Effects of interface mutations on the dimerization of alanine glyoxylate aminotransferase and implications in the mistargeting of the pathogenic variants F152I and I244T
2014 / The Journal of Biological Chemistry
Protein aggregation is linked to a growing list of diseases, but it is also an intrinsic property of polypeptides, because… Continue reading Amyloid Formation by Human Carboxypeptidase D Transthyretin-like Domain under Physiological Conditions
2014 / Physical Chemistry Chemical Physics
Spectroscopic studies combined with computational analysis indicate the inherent conformational flexibility of the β-carbolin derivative evodiamine (EVD) featured with diverse… Continue reading Role of the conformational flexibility of evodiamine in its binding to protein hosts: a comparative spectroscopic and molecular modeling evaluation with rutaecarpine
2013 / Molecular Pharmaceutics
Harmane and norharmane are representative members of the large group of natural β-carboline alkaloids featured with diverse pharmacological activities. In… Continue reading Fatty Acid Modulated Human Serum Albumin Binding of the β-Carboline Alkaloids Norharmane and Harmane
2014 / Neurobiology of Disease
Dementia with Lewy bodies (DLB), Parkinson’s disease (PD) and multiple system atrophy are characterized by the deposition of disease-associated α-synuclein. In the present… Continue reading Intracellular processing of disease-associated α-synuclein in the human brain suggests prion-like cell-to-cell spread
2007 / Biomacromolecules
Glycopolymers carrying sulfated saccharides with modest sugar contents (11% and 28%) were found to suppress the formation of amyloid fibrils… Continue reading Inhibition of Alzheimer Amyloid Aggregation with Sulfated Glycopolymers
2007 / Biophysical Journal
The major protein component of the amyloid deposition in Alzheimer’s disease is a 39–43 residue peptide, amyloid β (Aβ). Aβ is toxic to… Continue reading Time-Dependent DNA Condensation Induced by Amyloid β-Peptide
2008 / Journal of Molecular Structure
Prolonged exposure of hen egg white lysozyme to near-UV light results in an unusual fluctuating and red shift of fluorescence… Continue reading Photoexcitation of tryptophan groups induced reduction of disulfide bonds in hen egg white lysozyme
2011 / The Journal of Biological Chemistry
Ample evidence suggests that almost all polypeptides can either adopt a native structure (folded or intrinsically disordered) or form misfolded… Continue reading Binding with Nucleic Acids or Glycosaminoglycans Converts Soluble Protein Oligomers to Amyloid
