Found 9617 Results / Page 461 of 481
2016 / FEBS Letters
Many age-related neurodegenerative diseases, including Alzheimer Disease (AD), are elicited by an interplay of genetic, environmental, and dietary factors. Food… Continue reading Preferential interaction of the Alzheimer peptide Aβ‐(1‐42) with Omega‐3 containing lipid bilayers: structure and interaction studies
2016 / Methods in Molecular Biology
Proteolysis has been cited as an important contributor to cancer initiation and progression. One can take advantage of tumor-associated proteases… Continue reading Imaging Matrix Metalloproteinase Activity Implicated in Breast Cancer Progression
2016 / Scientific Reports
Electron paramagnetic resonance (EPR)-based hybrid experimental and computational approaches were applied to determine the structure of a full-length E. coli integral membrane… Continue reading Structure of an E. coli integral membrane sulfurtransferase and its structural transition upon SCN− binding defined by EPR-based hybrid method
2016 / Scientific Reports
Discovery of variable lymphocyte receptors (VLRs) in agnathans (jawless fish) has brought the origin of adaptive immunity system (AIS) forward… Continue reading Structure of a variable lymphocyte receptor-like protein from the amphioxusBranchiostoma floridae
2015 / RSC Advances
Catanionic vesicles are appealing vectors in non-viral gene transfection. They possess high kinetic stability and the preparation procedures are easy… Continue reading Catanionic vesicles and DNA complexes: a strategy towards novel gene delivery systems
2016 / Biological Macromolecules
Excessive melanin production leads to hyperpigmentation disorders which results in distressing aesthetic values. Though there are some synthetic depigmentation agents… Continue reading Functionality study of santalin as tyrosinase inhibitor: a potential depigmentation agent
2016 / Journal of Biomolecular Structure and Dynamics
Mitochondrial carbonic anhydrase VA (CAVA) catalyzes the hydration of carbon dioxide to produce proton and bicarbonate which is primarily expressed… Continue reading Effect of pH on structure, function and stability of mitochondrial carbonic anhydrase VA
2016 / Colloids and Surfaces B: Biointerfaces
In this study, Fe3O4@SiO2-cytarabine magnetic nanoparticles (MNPs) were prepared via chemical coprecipitation reaction and coating silica on the surface of… Continue reading Improving antiproliferative effect of the anticancer drug cytarabine on human promyelocytic leukemia cells by coating on Fe3O4@SiO2 nanoparticles
2016 / Chinese Chemical Letters
Four stereoisomers of 3,5-bis(2-hydroxybut-3-en-1-yl)-1,2,4-thiadiazole, named insatindigothiadiazoles A–D (1a–1d), were isolated from the roots of Isatis indigotica. Their structures were determined by… Continue reading Antiviral stereoisomers of 3,5-bis(2-hydroxybut-3-en-1-yl)-1,2, 4-thiadiazole from the roots of Isatis indigotica
2016 / Phytochemistry
A sulfated guaiane sesquiterpene lactone, an unusual pyridinium alkaloid with a sulfated guaiane sesquiterpene lactone nucleus, an amino conjugate of… Continue reading Sesquiterpenoids and tirucallane triterpenoids from the roots of Scorzonera divaricata
2016 / Journal of Molecular Structure
Four new Ru(II) DMSO complexes with substituted chalcone ligands viz. (E)-1-(2-hydroxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one (HL1), (E)-1-(2-hydroxyphenyl)-3-(4-nitrophenyl)prop-2-en-1-one (HL2), (E)-3-(4-(dimethylamino)phenyl)-1-(2-hydroxyphenyl)prop-2-en-1-one (HL3) and (E)-1-(2-hydroxyphenyl)-3-(4-Chlorophenyl)prop-2-en-1-one (HL4) have been synthesized, and characterized by micro-analyses, IR, 1H NMR,… Continue reading Synthesis, characterization and biological activities of some Ru(II) complexes with substituted chalcones and their applications as chemotherapeutics against breast cancer
2016 / Natural Product Research
Phytochemical investigation of the flowering aerial parts of Asteriscus maritimus (L.) Less (Asteraceae) led to the isolation of a new compound: patuletin… Continue reading A new acylated flavonol from the aerial parts of Asteriscus maritimus (L.) Less (Asteraceae)
2016 / Molecules
: Two new naphthalenones, corynenones A and B (1 and 2), and one new depsidone, corynesidone E (3), together with one known depsidone,… Continue reading Naphthalenones and Depsidones from a Sponge-Derived Strain of the Fungus Corynespora cassiicola
2016 / Biochimica et Biophysica Acta
ICA512 (or IA-2/PTPRN) is a transmembrane protein-tyrosine phosphatase located in secretory granules of neuroendocrine cells. Previous studies implied its involvement… Continue reading Biochemical, biophysical, and functional properties of ICA512/IA-2 RESP18 homology domain
2016 / Biomolecules
Hydrophobins are fungal proteins whose functions are mainly based on their capability to self-assemble into amphiphilic films at hydrophobic–hydrophilic interfaces… Continue reading Class I Hydrophobin Vmh2 Adopts Atypical Mechanisms to Self-Assemble into Functional Amyloid Fibrils
2016 / Food Chemistry
The rAra h 2.02 was studied to determine the influence of heat treatment on its structure and core IgE-binding epitopes.… Continue reading Influence of heat treatment on the structure and core IgE-binding epitopes of rAra h 2.02
2015 / Small
A metal-coordinated α-helical peptide monolayer shows exceptional vectorial electron transfer. It also displays rectification behavior whereby an alternating current signal is… Continue reading Piezoelectric-Enhanced Oriented Cobalt Coordinated Peptide Monolayer with Rectification Behavior
2015 / Transactions of the Materials Research Society of Japan
The amino acid sequence of vanillin-binding site of transient receptor potential vanilloid type 1 from rat, Leu544–Tyr553, was extracted and… Continue reading Synthesis and Self-Assembly of His-tag Hybrid of Substrate-Binging Short Domain in Transient Receptor Potential Vanilloid Type 1 for Vanillin Sensing Application
2015 / Journal of Biomolecular Structure and Dynamics
MAP/microtubule affinity-regulating kinase 4 (MARK4) is a member of adenosine monophosphate-activated protein kinases, directly associated with cancer and neurodegenerative diseases.… Continue reading Human microtubule affinity-regulating kinase 4 is stable at extremes of pH
2015 / PLoS ONE
The denatured states of proteins have always attracted our attention due to the fact that the denatured state is the… Continue reading Cooperative Unfolding of Residual Structure in Heat Denatured Proteins by Urea and Guanidinium Chloride
