Two thia-heterohelicenes of different length, namely a hetero [4]-helicene (1), and a hetero [6]-helicene (2) are studied by electronic circular… Continue reading Chiroptical properties of the ground and excited states of two thia-bridged triarylamine heterohelicenes
Leah Pandiscia, PhD
May 24, 2018
Clinically, the amount of uric acid (UA) in biological fluids is closely related to some diseases such as hyperuricemia and… Continue reading Label-free and selective sensing of uric acid with gold nanoclusters as optical probe
Leah Pandiscia, PhD
July 28, 2017
The influence of metal cations on G-quadruplex structure and peroxidase-mimicking DNAzyme activity was investigated. Experiments revealed a significant role of… Continue reading Hemin/G-quadruplex structure and activity alteration induced by magnesium cations
Leah Pandiscia, PhD
July 28, 2017
Aggregation of globular proteins is an intractable problem which generally originates from partially folded structures. The partially folded structures first… Continue reading Physical basis for the ofloxacin-induced acceleration of lysozyme aggregation and polymorphism in amyloid fibrils
Leah Pandiscia, PhD
July 28, 2017
The present paper describes the fabrication of nanovesicles using the stirring induced self-assembly of a β-alanine homotetramer (H2N–βAla–βAla–βAla–βAla–CONH2) in an… Continue reading Self-assembly of β-alanine homotetramer: formation of nanovesicles for drug delivery
Leah Pandiscia, PhD
July 28, 2017
The structure of peptide antibiotic gramicidin A (gA) was studied in phosphatidylcholin liposomes modified by nonionic detergent Triton X-100. First,… Continue reading Effective lipid-detergent system for study of membrane active peptides in fluid liposomes
Leah Pandiscia, PhD
July 28, 2017
In this study, the isolation, the structural characterization, and the elucidation of the biosynthetic origin of heterobactins, catecholate-hydroxamate mixed-type siderophores… Continue reading Structural Characterization of the Heterobactin Siderophores from Rhodococcus erythropolis PR4 and Elucidation of their Biosynthetic Machinery.
Leah Pandiscia, PhD
July 28, 2017
The binding mode of a conformationally locked single bondNC(O)Nsingle bond planar system with deoxyribonucleic acid (DNA) is investigated using various spectroscopic and… Continue reading Alteration in DNA binding pattern of conformationally locked NC(O)N system: A spectroscopic investigation
Leah Pandiscia, PhD
July 28, 2017
Bisphenols (BPs) are a group of chemicals with two hydroxyphenyl functionalities. BPs analogues including bisphenol A (BPA), bisphenol B (BPB),… Continue reading Bisphenol analogues differently affect human islet polypeptide amyloid formation
Leah Pandiscia, PhD
July 28, 2017
Kallikrein, a physiologically vital serine protease, was investigated for its functional and conformational transitions during chemical (organic solvents, Gdn-HCl), thermal,… Continue reading Functional Stability and Structural Transitions of Kallikrein: Spectroscopic and Molecular dynamics studies
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Chemical investigation of the cultures of marine Streptomyces sp. 182SMLY led to the discovery of two new polycyclic anthraquinones, which were elucidated… Continue reading Bioactive Polycyclic Quinones from Marine Streptomyces sp. 182SMLY
Leah Pandiscia, PhD
July 28, 2017
Fluorescence anisotropy, known as a simple, homogeneous and cost-effective analytical technology, is an invaluable technique for studying the micro-environmental changes… Continue reading Modulating fluorescence anisotropy of dye-labeled DNA without involving mass amplification
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Assemblies with helical fiber nanostructures were fabricated via simple ionic linkage of a cationic tetraphenylethylene derivative (TPEHexN+) and an anionic binaphthyl derivative… Continue reading The fabrication of helical fibers with circularly polarized luminescence viaionic linkage of binaphthol and tetraphenylethylene derivatives
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Two new heterotrinuclear Fe–Ru–Fe complexes of ruthenium(II) tetraphenylporphyrin axially coordinated with a pair of isocyanoferrocene ((FcNC)2RuTPP, 1) or 1,1′-diisocyanoferrocene (([C5H4NC]2Fe)2RuTPP, 2) ligands… Continue reading Probing Electronic Communications in Heterotrinuclear Fe−Ru−Fe Molecular Wires Formed by Ruthenium(II) Tetraphenylporphyrin and Isocyanoferrocene or 1,1′-Diisocyanoferrocene Ligands
Leah Pandiscia, PhD
July 28, 2017
An ultrarapid-mixing continuous-flow method has been developed to study submillisecond folding of chemically denatured proteins. Turbulent flow created by pumping… Continue reading Submillisecond protein folding kinetics studied by ultrarapid mixing
Leah Pandiscia, PhD
July 28, 2017
Two new neo-lignans, erythro-7E-4′,9′-dihydroxy-4,5′-dimethoxy-5,8′-oxyneolign-7-en-9-al (1) and 4,5′-dimethoxy-lariciresinol (2) together with five known compounds (3-7) were isolated from the EtOAc-soluble extract of Eleutherococcus… Continue reading Inhibition effect of neo-lignans from Eleutherococcus senticosus (Rupt. & Maxim.) Maxim on diacylglycerol acyltransferase (DGAT)
Leah Pandiscia, PhD
July 28, 2017
Recent studies have characterized the effects of aqueous ionic liquids on myoglobin unfolding for the broader purposes of understanding their… Continue reading Kinetics and mass spectrometric measurements of myoglobin unfolding in aqueous ionic liquid solutions
Leah Pandiscia, PhD
July 28, 2017