Found 9617 Results / Page 472 of 481
2016 / Bioorganic and Medicinal Chemistry
The Cu(I)-catalyzed alkyne–azide cycloaddition (CuAAC) has become increasingly important in the conjugation chemistry of biomolecules. For example, it is an… Continue reading Anionic surfactants enhance click reaction-mediated protein conjugation with ubiquitin
2016 / Journal of Molecular Biology
Redβ is a component of the Red recombination system of bacteriophage λ that promotes a single strand annealing (SSA) reaction… Continue reading Domain Structure of the Redβ Single-Strand Annealing Protein: the C-terminal Domain is Required for Fine-Tuning DNA-binding Properties, Interaction with the Exonuclease Partner, and Recombination in vivo
2016 / Dyes and Pigments
5,10,15,20-tetra-(N-methyl-2-pyridyl)porphyrin (TMPyP2) was always paid little attention because it has relatively low DNA-binding affinity and photocytotoxicity compared with its positional… Continue reading G-quadruplex DNA interactions, docking and cell photocytotoxicity research of porphyrin dyes
2016 / Journal of Biomedical Science
Homeostasis of reactive oxygen species (ROS) in the skin is regulated by antioxidant defenses. The inflammatory states of skin diseases… Continue reading Therapeutic evaluation of HIV transduction basic domain-conjugated superoxide dismutase solution on suppressive effects of the formation of peroxynitrite and expression of COX-2 in murine skin
2016 / Journal of Materials Chemistry B
Early disease diagnosis is very important for the prevention or mitigation of metastasis. Effective and efficient methods are needed to… Continue reading Three label-free thrombin aptasensors based on aptamers and [Ru(bpy)2(o-mopip)]2+
2016 / Biophysical Journal
Lactophoricin (LPcin), a component of proteose peptone (113–135) isolated from bovine milk, is a cationic amphipathic antimicrobial peptide consisting of… Continue reading NMR Structural Studies of Antimicrobial Peptides: LPcin Analogs
2016 / Biochemical and Biophysical Research Communications
Protein conformational changes are fundamental to biological reactions. For copper ion transport, the multi-domain protein ATP7B in the Golgi network… Continue reading Copper binding triggers compaction in N-terminal tail of human copper pump ATP7B
2016 / International Journal of Biological Macromolecules
Immunochemical studies on HNE-modified HSA: Anti-HNE–HSA antibodies as a probe for HNE damaged albumin in SLE
2016 / RSC Advances
Two peptides, Coil-K and Coil-E, form a parallel heterodimeric coiled coil, CC-K/E, and have been shown to promote membrane fusion.… Continue reading A non-zipper-like tetrameric coiled coil promotes membrane fusion
2016 / Organometallics
Arene Ru(II) complexes have long been extensively studied as potential inhibitors against the proliferation of tumor cells, but their behavior… Continue reading Arene Ruthenium(II) Complexes as Low-Toxicity Inhibitor against the Proliferation, Migration, and Invasion of MDA-MB-231 Cells through Binding and Stabilizing c-myc G-Quadruplex DNA
2016 / Polyhedron
New [RuCl2(1,5cod)(L1)] (1), [RuCl2(1,5cod)(L2)] (2), [RuCl2(1,5cod)(L3)] (3), [RuCl2(1,5cod)(L4)] (4), [RuCl2(1,5cod)(L5)] (5) (L = (p-R-N-(pyridin-2-ylmethylene)aniline), R = H (L1), Cl (L2), OCH3 (L3), CH3 (L4), L5 = (9-ethyl-N-(pyridin-2-ylmethylene)9H-carbazole-3-amine and 1,5cod = η4-cyclooctadiene)… Continue reading Binding interaction, conformational change, and molecular docking study of N-(pyridin-2-ylmethylene)aniline derivatives and carbazole Ru(II) complexes with human serum albumins
2016 / Heteroatom Chemistry
An efficient resolution method was elaborated for the preparation of (+)-4-chloro-5-methyl-1-phenyl-1,2,3,6-tetrahydrophosphinine oxide using the acidic Ca2+ salt of (–)-O,O-di-p-toluoyl-(2R,3R)-tartaric acid. Crystal… Continue reading Synthesis, Characterization, and Application of Platinum(II) Complexes Incorporating Racemic and Optically Active 4-Chloro-5-Methyl-1-Phenyl-1,2,3,6-Tetrahydrophosphinine Ligand
2016 / The Journal of Physical Chemistry B
Antifreeze proteins (AFPs) are the key biomolecules that enable species to survive under subzero temperature conditions. The physiologically relevant activities… Continue reading Structure and Dynamics of Antifreeze Protein – Model Membrane Interactions: A Combined Spectroscopic and Molecular Dynamics Study
2016 / Nanoscale
DNA-based molecular logic computation has drawn extensive attention in bioanalysis, intelligent diagnostics of diseases and other nanotechnology areas. Herein, taking… Continue reading Label-free and enzyme-free platform for the construction of advanced DNA logic devices based on the assembly of graphene oxide and DNA-templated AgNCs
2016 / Journal of Materials Chemistry C
A new optical material based on the self-assembly of a low-molecular organogelator-linked anthracene derivative for the control of the fluorescence… Continue reading Tunable Stokes shift and circularly polarized luminescence by supramolecular gel
2015 / Journal of Biochemical and Molecular Toxicology
The interaction of hydroxyethyl starch 130/0.4 (Voluven) with human serum albumin (HSA) has been investigated by fluorescence (steady state and… Continue reading Investigation on the Interaction of Hydroxyethyl Starch 130/0.4 (Voluven) and Serum Albumin for Pharmacokinetic and Toxicological Implications
2016 / IUBMB Life
In our study buffalo kidney cystatin (BKC) is transformed from native conformation to amyloid fibrils when incubated with 20 mM… Continue reading Glyoxal induced structural transition of buffalo kidney cystatin to molten globule and aggregates: Anti-fibrillation potency of quinic acid
2016 / Materials Science and Engineering: C
Cry1Ab16 is a toxin of crystalline insecticidal proteins that has been widely used in genetically modified organisms (GMOs) to gain… Continue reading Layer-by-layer films containing peptides of the Cry1Ab16 toxin from Bacillus thuringiensis for potential biotechnological applications
2016 / Inorganica Chimica Acta
New Cu(II), Pd(II) and Pt(II) complexes with 2,2-thiophen-yl-imidazole (Thim) were synthesized. Elemental and MS analyses indicate the [MCl2(Thim)2] composition. The… Continue reading Copper(II), palladium(II) and platinum(II) complexes with 2,2-thiophen-yl-imidazole: Synthesis, spectroscopic characterization, X-ray crystallographic studies and interactions with calf-thymus DNA
2016 / Journal of Polymer Science Part A
Herein we present the synthesis and polycondensation of mono- and di-N-protected, bis-substituted tri(benzamide)s with the aim to create large, tubular helices.… Continue reading Toward large tubular helices based on the polymerization of tri(benzamide)s
