Found 9617 Results / Page 92 of 481

Donor strand sequence, rather than donor strand orientation, determines the stability and non-equilibrium folding of the type 1 pilus subunit FimA

2020 / Journal of Biological Chemistry

FimA is the main structural subunit of adhesive type 1 pili from uropathogenic Escherichia coli strains. Up to 3000 copies of FimA… Continue reading Donor strand sequence, rather than donor strand orientation, determines the stability and non-equilibrium folding of the type 1 pilus subunit FimA

Leah Pandiscia, PhD

Enantiomerically Pure Quinoline-Based k-Opioid Receptor Agonists: Chemoenzymatic Synthesis and Pharmacological Evaluation

2020 / ChemMedChem

Racemic K‐opioid receptor (KOR) agonist 2‐(3,4‐dichlorophenyl)‐1‐[(4aRS ,8SR ,8aSR )‐8‐(pyrrolidin‐1‐yl)‐3,4,4a,5,6,7,8,8a‐octahydroquinolin‐1(2H )‐yl]ethan‐1‐one ((±)‐4 ) was prepared in a diastereoselective synthesis. The first key step of the synthesis was… Continue reading Enantiomerically Pure Quinoline-Based k-Opioid Receptor Agonists: Chemoenzymatic Synthesis and Pharmacological Evaluation

Leah Pandiscia, PhD

Synthesis and Docking Study of N-(Cinnamoyl)-N′-(Substituted)acryloyl Hydrazide Derivatives Containing Pyridinium Moieties as a Novel Class of FtsZ Inhibitors against the Intractable Xanthomonas oryzae pv. oryzae Infections in Rice

2020 / Journal of Agriculture and Food Chemistry

Xanthomonas oryzae pv. oryzae (Xoo) is an offensive phytopathogen that can invade a wide range of plant hosts to develop… Continue reading Synthesis and Docking Study of N-(Cinnamoyl)-N′-(Substituted)acryloyl Hydrazide Derivatives Containing Pyridinium Moieties as a Novel Class of FtsZ Inhibitors against the Intractable Xanthomonas oryzae pv. oryzae Infections in Rice

Leah Pandiscia, PhD

Role of Side-Chain and Chirality of the Amino acids on the Supramolecular Assemblies of Dipeptides

2020 / Journal of Molecular Structure

The supramolecular self-association of alternating L/L and L/D amino acid-containing dipeptides, Boc-L-Ile-L-Phe-OMe (1), Boc-L-Ile-D-Phe-OMe (2), Boc-L-Ile-L-Phg-OMe (3, Phg = phenylglycine), and Boc-L-Ile-D-Phg-OMe… Continue reading Role of Side-Chain and Chirality of the Amino acids on the Supramolecular Assemblies of Dipeptides

Leah Pandiscia, PhD

Mutational analysis of the essential lipopolysaccharide-transport protein LptH of Pseudomonas aeruginosa to uncover critical oligomerization sites

2020 / Scientific Reports

Lipopolysaccharide (LPS) is a critical component of the outer membrane (OM) of many Gram-negative bacteria. LPS is translocated to the… Continue reading Mutational analysis of the essential lipopolysaccharide-transport protein LptH of Pseudomonas aeruginosa to uncover critical oligomerization sites

Leah Pandiscia, PhD

A comparison study between novel ternary retrieval NiFe2O4@P-doped g-C3N4 and Fe3O4@P-doped g-C3N4 nanocomposite in the field of photocatalysis, H2 energy production and super capacitive property

2020 / Materials Today: Proceedings

In this paper, we report the synthesis of magnetically separable stable phosphors doped g-C3N4@NiFe2O4 and phosphors doped g-C3N4@Fe3O4 nanocomposite with their application… Continue reading A comparison study between novel ternary retrieval NiFe2O4@P-doped g-C3N4 and Fe3O4@P-doped g-C3N4 nanocomposite in the field of photocatalysis, H2 energy production and super capacitive property

Leah Pandiscia, PhD

Homochiral Helical Coordination Architectures Built from Biphenyl-Based Amino Acid Derivatives: Structural Diversity Tuned by Varying Conformation and Configuration of N-donor ligands, Sensing of Acidic Amino Acids and Photoluminescence Properties

2020 / Crystal Growth & Design

Self-assembly of divalent metal ions and designed amino acid derivatives, 4,4′-biphenyl-bis[carbonyl-N-(alanine)] (H2BPBAla) and 4,4′-biphenyl-bis[carbonyl-N-(proline)] (H2BPBPro), as well as ancillary ligands,… Continue reading Homochiral Helical Coordination Architectures Built from Biphenyl-Based Amino Acid Derivatives: Structural Diversity Tuned by Varying Conformation and Configuration of N-donor ligands, Sensing of Acidic Amino Acids and Photoluminescence Properties

Leah Pandiscia, PhD

Comparison and optimization of extraction methods of extracellular polymeric substances in anammox granules: From maintaining protein secondary structure perspective

2020 / Chemosphere

Extracellular proteins are crucial for the formation and structural maintenance of anammox granules. However, the influence of extracellular polymeric substances… Continue reading Comparison and optimization of extraction methods of extracellular polymeric substances in anammox granules: From maintaining protein secondary structure perspective

Leah Pandiscia, PhD

Use of Tris-NH4Cl in modified G4/hemin DNAzyme assay with duplexed probes extends life of colorized radical product

2020 / Sensors and Actuators B: Chemical

The split G-quadruplex/hemin DNAzyme exhibits peroxidase-like activity and catalyzes the oxidation of colorless 2,2′-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS2−) to the green-colored… Continue reading Use of Tris-NH4Cl in modified G4/hemin DNAzyme assay with duplexed probes extends life of colorized radical product

Leah Pandiscia, PhD

Functional and structural evaluation of the antileukaemic enzyme L-asparaginase II expressed at low temperature by different Escherichia coli strains

2020 / Biotechnology Letters

Acute lymphoblastic leukaemia (ALL) affects lymphoblastic cells and is the most common neoplasm during childhood. Among the pharmaceuticals used in… Continue reading Functional and structural evaluation of the antileukaemic enzyme L-asparaginase II expressed at low temperature by different Escherichia coli strains

Leah Pandiscia, PhD

The Multifaceted Effects of DMSO and High Hydrostatic Pressure on the Kinetic Constants of Hydrolysis Reactions Catalyzed by α-Chymotrypsin

2020 / Physical Chemistry Chemical Physics

The use of cosolvents and high hydrostatic pressure (HHP) has been described as an efficient means to modulate the stability… Continue reading The Multifaceted Effects of DMSO and High Hydrostatic Pressure on the Kinetic Constants of Hydrolysis Reactions Catalyzed by α-Chymotrypsin

Leah Pandiscia, PhD
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