Leah Pandiscia, PhD
July 30, 2020
Racemic K‐opioid receptor (KOR) agonist 2‐(3,4‐dichlorophenyl)‐1‐[(4aRS ,8SR ,8aSR )‐8‐(pyrrolidin‐1‐yl)‐3,4,4a,5,6,7,8,8a‐octahydroquinolin‐1(2H )‐yl]ethan‐1‐one ((±)‐4 ) was prepared in a diastereoselective synthesis. The first key step of the synthesis was… Continue reading Enantiomerically Pure Quinoline-Based k-Opioid Receptor Agonists: Chemoenzymatic Synthesis and Pharmacological Evaluation
Leah Pandiscia, PhD
July 30, 2020
Leah Pandiscia, PhD
July 30, 2020
The supramolecular self-association of alternating L/L and L/D amino acid-containing dipeptides, Boc-L-Ile-L-Phe-OMe (1), Boc-L-Ile-D-Phe-OMe (2), Boc-L-Ile-L-Phg-OMe (3, Phg = phenylglycine), and Boc-L-Ile-D-Phg-OMe… Continue reading Role of Side-Chain and Chirality of the Amino acids on the Supramolecular Assemblies of Dipeptides
Leah Pandiscia, PhD
July 30, 2020
Leah Pandiscia, PhD
July 30, 2020
Colloidal metal halide perovskite nanocrystals (NCs) with chiral ligands are outstanding candidates as a circularly polarized luminescence (CPL) light source… Continue reading Strategies to Achieve High Circularly Polarized Luminescence from Colloidal Organic-Inorganic Hybrid Perovskite Nanocrystals
Leah Pandiscia, PhD
July 30, 2020
A cold-active transglutaminase (TGase, EC 2.3.2.13) that catalyzes the reaction of protein glutamine + protein lysine ↔ protein with γ-glutamyl-ε-lysine… Continue reading Contribution of Special Structural Features to High Thermal Stability of a Cold-active Transglutaminase
Leah Pandiscia, PhD
July 30, 2020
Biomimetic design represents an emerging field for improving knowledge of natural molecules, as well as to project novel artificial tools… Continue reading Novel atrazine-binding biomimetics inspired to the D1 protein from the photosystem II of Chlamydomonas reinhardtii
Leah Pandiscia, PhD
July 30, 2020
Leah Pandiscia, PhD
July 30, 2020
The use of luminescent solar concentrators (LSCs) is considered a promising solution for harvesting indoor and outdoor light energy. Despite… Continue reading Indoor/outdoor light-harvesting by coupling low-cost organic solar cell with a luminescent solar concentrator
Leah Pandiscia, PhD
July 30, 2020
Leah Pandiscia, PhD
July 30, 2020
Leah Pandiscia, PhD
July 30, 2020
The split G-quadruplex/hemin DNAzyme exhibits peroxidase-like activity and catalyzes the oxidation of colorless 2,2′-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS2−) to the green-colored… Continue reading Use of Tris-NH4Cl in modified G4/hemin DNAzyme assay with duplexed probes extends life of colorized radical product
Leah Pandiscia, PhD
July 30, 2020
The self-microemulsifying delivery system was fabricated by whey protein isolate (WPI), daidzein (Dai) and surfactants, the interaction of WPI, Dai… Continue reading Interaction among protein, daidzein and surfactants in the WPI-based daidzein self-microemulsifying delivery system
Leah Pandiscia, PhD
July 30, 2020
Leah Pandiscia, PhD
July 30, 2020
Leah Pandiscia, PhD
July 30, 2020
Leah Pandiscia, PhD
July 30, 2020
DNA-DNA reactions can be monitored with a label-free fluorogenic reaction. Guanosine-rich, single-stranded DNA oligonucleotides bind to thioflavin-T (ThT) and enhance… Continue reading Thioflavin T as a noncovalent reporter for a label-free, non-enzymatic, catalytic DNA amplifier
Leah Pandiscia, PhD
July 30, 2020
Leah Pandiscia, PhD
July 30, 2020
In Brazil, Plasmodium vivax infection accounts for around 80% of malaria cases. This infection has a substantial impact on the productivity of… Continue reading Plasmodium vivax AMA1: Implications of distinct haplotypes for immune response
Leah Pandiscia, PhD
July 30, 2020