2012 / Journal of Asian Natural Products Research
Two new ent-3,4-seco-labdane diterpenoids, methylcallicarpate (1) and callicarpic acid (2), were isolated from the leaves of Callicarpa nudiflora Hook et Arn. Their… Continue reading Two new ent-3,4-seco-labdane diterpenoids from Callicarpa nudiflora
2013 / The Journal of Biological Chemistry
Extracellular Tat is suspected to protect HIV-1-infected cells from cellular immunity. Seropositive patients are unable to produce neutralizing antibodies against… Continue reading Identification of a Highly Conserved Surface on Tat Variants
2014 / FEBS Letters
The mitochondrial targeting signal in the presequence of mitochondrial precursor proteins is recognized by Tom20 and subsequently by Tim50 in… Continue reading NMR analyses on the interactions of the yeast Tim50 C-terminal region with the presequence and Tim50 core domain
2012 / Angewandte Chemie
The transfer and trapping of holes in a G-quadruplex were investigated by laser flash photolysis and pulse radiolysis . The… Continue reading Hole Trapping of G-Quartets in a G-Quadruplex
2012 / Angewandte Chemie
Thiolate-protected Au40(SR)24 clusters were enantioenriched using an HPLC approach. CD spectra show strong mirror-image responses, indicating the intrinsic chirality of… Continue reading Separation of Enantiomers and CD Spectra of Au40(SCH2CH2Ph)24: Spectroscopic Evidence for Intrinsic Chirality
2014 / Biophysical Chemistry
α-Defensins (e.g. human neutrophil peptides, HNPs) have a broad spectrum bactericidal activity contributing to human innate immunity. The positive charge… Continue reading Human neutrophil peptide 1 variants bearing arginine modified cationic side chains: Effects on membrane partitioning
2015 / Designed Monomers and Polymers
A series of thiophene-based chiral small bandgap π-conjugated polymers was successfully synthesized. Optical properties of the polymers were investigated by… Continue reading Thiophene-based chiral small bandgap π-conjugated polymers: synthesis and optical properties
2014 / Polymer Chemistry
Protein polymers can assemble switchable nanostructures with emerging applications as biomaterials and nanomedicines. For example, above a critical micelle temperature… Continue reading A quantitative recipe for engineering protein polymer nanoparticles
2014 / Fitoterapia
One megastigmane derivative 1, one methyl jasmonate glycoside derivative 2, and two C-28 steroids with 3β,5β-cis-dihydroxyl conformation 3 and 4, together with eight known compounds 5–12 were… Continue reading Chemical constituents from the linseed meal
2014 / PROTEOMICS - Clinical Applications
In this study, we investigated whether the phenotypic difference observed between two lattice corneal dystrophy type 1 (LCD type 1)… Continue reading Comparison of two phenotypically distinct lattice corneal dystrophies caused by mutations in the transforming growth factor beta induced (TGFBI) gene
2012 / Food Chemistry
Peanut allergy is recognized as one of the most severe food allergies. The aim of this study was to investigate… Continue reading Heat and pressure treatments effects on peanut allergenicity
2016 / Biophysical Journal
Protein-nucleic acid interactions are central to a variety of biological processes, many of which involve large-scale conformational changes that lead… Continue reading Binding by TRBP-dsRBD2 Does Not Induce Bending of Double-Stranded RNA
2013 / Tetrahedron
Four new compounds, rearranged noreremophilan-8,6-olide, rearranged dinoreremophilanone, epoxy γ-lactone, and 2α-hydroxyermophil-11-en-9-one, along with eremophilenolides related to ligularol and other known… Continue reading Four new compounds from Ligularia virgaurea: isolation of eremophilane and noreremophilane sesquiterpenoids and the absolute configuration of 2α-hydroxyeremophil-11-en-9-one by CD spectrum and DFT calculation
2015 / Peptides
The recent observation that certain cationic peptides possess potent antibiofilm activity demonstrated that small peptides could be used to treat… Continue reading High throughput screening methods for assessing antibiofilm and immunomodulatory activities of synthetic peptides
2014 / Journal of Molecular Biology
The tumor suppressor protein Merlin inhibits cell proliferation upon establishing cell–cell contacts. Because Merlin has high level of sequence similarity… Continue reading Molecular Conformation of the Full-Length Tumor Suppressor NF2/Merlin—A Small-Angle Neutron Scattering Study
2012 / Vaccine
Current Hepatitis B vaccines are based on recombinant Hepatitis B surface antigen (HBsAg) virus-like particles adsorbed on aluminium (Al) gel.… Continue reading The structure of HBsAg particles is not modified upon their adsorption on aluminium hydroxide gel
2014 / ChemBioChem
We report an investigation into analogues of the thrombin binding aptamer (TBA). Individual thymidines were replaced by the unusual residue… Continue reading 5-Hydroxymethyl-2′-Deoxyuridine Residues in the Thrombin Binding Aptamer: Investigating Anticoagulant Activity by Making a Tiny Chemical Modification
2016 / Carbohydrate Polymers
In a rapid one-step method protein-mimicking large agarose amino acid framework (AAE; GPC 156.7 kDa) was conjugated with polyethylene glycol (PEG… Continue reading Agarose functionalization: Synthesis of PEG-agarose amino acid nano-conjugate – its structural ramifications and interactions with BSA in a varying pH regime
2016 / Journal of Colloid and Interface Science
Colloidal chirality in wormlike micellar systems exclusively originated from achiral species and discussion of the role of secondary assembly of… Continue reading Colloidal chirality in wormlike micellar systems exclusively originated from achiral species: Role of secondary assembly and stimulus responsivity
2016 / Journal of Inorganic Biochemistry
Four copper(II) complexes of the general structure [Cu(L1)(L2)]2 +, where L1 is (1S,2S)-diaminocyclohexane or (1R,2R)-diaminocyclohexane and L2 is 3,4,7,8-tetramethyl-1,10-phenanthroline (TMP) or 4,7-diphenyl-1,10-phenanthroline (DIP),… Continue reading The antimicrobial efficacy and DNA binding activity of the copper(II) complexes of 3,4,7,8-tetramethyl-1,10-phenanthroline, 4,7-diphenyl-1,10-phenanthroline and 1,2-diaminocyclohexane
